BURDEN OF DISEASE PREVALENCE AND INCIDENCE OF RENAL DISEASE (ESRD) IN LATIN AMERICA GUILLERMO GARCÍA GARCÍA on behalf of [email protected] MAIN POINTS •Demographic and socioeconomic characteristics of Latin America •Latin America Dialysis and Renal Transplant Registry (LADTR) outcomes •RRT prevalence & incidence in all modalities •renal transplants •correlation with socioeconomic variables DEMOGRAPHIC AND SOCIOECONOMIC CHARACTERISTICS LATIN AMERICA •Extended from Río Bravo (México) in the North to Tierra del Fuego (Argentina) in the South •Share the language: Spanish or Portuguese and a wide ethnic diversity •Surface area: 22 522 000 millions km2 (13.5% of emerging surface of the planet) •Population: 588.640.000 * •Annual population growth rate 2000-2012: 1,1% * •Urban population: 79.3% * •Life expectancy at birth: 74 years* •Older than 65 years : 7% * •Gross national income: U$D U$ 5,477 billions * •Gross national income per capita: U$D $ 9314 * •Literacy rate: 93% male y 92% female * •Human development index: 0.741 ** * http://www.worldbank.org ** www.undp.org LATIN AMERICA SIGNIFICANT IMPROVEMENT OF SOCIOECONOMICS INDICATORS • • • • • • Life expectancy at birth: 68 to 74 years (1990-2010) GNI: U$D 2784 to U$D 9314 (1991-2012) • Nicaragua & Haiti are still in the group of low income (< 1200 U$D) • 5 countries are in the group of lower middle income (1200-3580) • 7 countries are in the group of upper middle income (3580-7980) • 6 countries are in the group of high income (7980-23610) • only Puerto Rico is in the group of very high income % of population living below poverty line (1999-2010) from 22.4 to10.4% % of population living below absolute poverty line (1997-2010) from 12.0 to 5.5% mean health expenditure per capita U$D 713 HDI: 0.705 a 0.741 LIFE EXPECTANCY AT BIRTH BOTH SEXES 2012 HUMAN DEVELOPMENT INDEX 2012 INEQUALITY 2013 LADRTR SWOT ANALYSIS WEAKNESSES voluntary reporting wide variability in the data consistency until 2010 Mexico data were extrapolated from state Registries (Morelos & Guadalajara) the number of patients living with a functioning kidney graft many times is an estimation STRENGHTS continuity along the time since 1991 contributed to the development of National Registries allowed to make comparisons among different countries and with other registries established the trends in the treatment of CKD in LA • • Costa Rica Bolivia Honduras El Salvador Panamá Rep Dominicana Paraguay Nicaragua Cuba YEAR 1992 Guatemala Uruguay Colombia Ecuador DATA FROM 18 COUNTRIES Perú TOTAL NUMBER OF RRT PATIENTS: 53.950 Puerto Rico – HD: 34.497 – PD: 17.162 – FKG: 2.291 Brasil Chile Venezuela Argentina México • • Rep Dominicana Costa Rica Panamá Bolivia Guatemala Cuba YEAR 2011 Uruguay Honduras DATA FROM 20 COUNTRIES El Salvador Paraguay Puerto Rico TOTAL NUMBER OF RRT PATIENTS 358.978 Nicaragua Ecuador – HD: 224.764 Perú – PD: 73.761 – FKG: 60.453 Venezuela Brasil Chile Colombia If this extrapolation was correct, the number of RRT patients of Mexico would be about 1/3 of the amount of Latin American RRT patients Argentina México OUTCOMES RRT PREVALENCE IN LATIN AMERICA (1991 – 2012) 800 700 568 PATIENTS PMP 600 522 500 400 335 352 300 200 258 147 119 129 131 173 174 278 199 100 0 YEAR 387 424 443 478 473 605 626 613 601 RRT PREVALENCE IN LATIN AMERICA (1991 – 2013) (preliminary data) 800 700 568 PATIENTS PMP 600 522 500 400 335 352 300 200 258 147 119 129 131 173 174 387 278 199 100 0 YEAR 424 443 478 473 605 627 626 613 601 RRT PREVALENCE IN LATIN AMERICA BY COUNTRY YEAR 2012 Puerto Rico 1740,1 Jalisco 1427,6 Chile 1239,4 Uruguay 1038,3 Argentina 833,1 Brasil 663,2 Colombia 564,4 El Salvador 556,1 Venezuela 477,7 Panamá 472,7 Ecuador 456,4 Perú 351,4 Costa Rica 329,8 Cuba 326,8 Bolivia 222,4 Rep Dominicana 185,1 Honduras 180 Paraguay 177,1 Guatemala 134,5 Nicaragua 63,9 0 200 400 600 800 1000 PMP 1200 1400 1600 1800 2000 EVOLUTION OF NUMBER OF RRT PATIENTS IN LATIN AMERICA BY TREATAMENT MODALITY (1991 – 2012) 250.000 HD DP KFG 150.000 100.000 50.000 YEAR 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 96/97 1995 1994 1993 0 1992 Nº OF PATIENTS 200.000 RRT PREVALENCE IN LATIN AMERICA. YEAR 2012 LATIN AMERICA Nicaragua Guatemala Paraguay Honduras Rep Dominicana Bolivia Cuba Costa Rica Perú Ecuador Panamá Venezuela El Salvador Colombia * Brasil Argentina * Uruguay Chile Jalisco Puerto Rico 601 PMP HD PD KFG ẋ = 569 PMP 0 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1800 PATIENTS PMP PREVALENCE OF RRT IN LATIN AMERICA. YEAR 2012 HD PD KFG Honduras Ecuador Paraguay Chile Rep Dominicana Bolivia Nicaragua Argentina * Cuba Venezuela Puerto Rico Perú Brasil Panamá Uruguay Guatemala Colombia * Jalisco El Salvador Costa Rica 0% 20% 40% PATIENTS % 60% 80% 100% PREVALENCE OF PD IN LATIN AMERICA. YEAR 2012 Paraguay Cuba Nicaragua Rep Dominicana Honduras Bolivia Costa Rica Guatemala Argentina * Ecuador Perú Brasil Chile Venezuela Uruguay Panamá Puerto Rico Colombia * El Salvador Jalisco -50 5 10 11 12 16 17 20 24 35 39 41 41 58 61 71 88 93 143 331 449 50 150 250 PATIENTS PMP 350 450 RRT INCIDENCE IN LATIN AMERICA. YEAR 2012 Honduras Ecuador Chile Brasil Argentina Uruguay Cuba Bolivia Colombia Nicaragua Perú Jalisco Paraguay Guatemala ẋ = 121 PMP 0 100 200 300 PATIENTS PMP 400 500 RENAL TRANSPLANTATION RENAL TRANSPLANTATION RATE IN LATIN AMERICA 1987-2012 25 19,5 19,1 20 18,1 15 13,6 13,7 9,8 10,5 9,5 10 5 14,5 15 10,8 6,4 5,9 5,7 5,2 5,4 10,2 13,2 13,7 16,9 7,4 6,9 3,7 YEAR 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1996 1995 1994 1993 1992 1991 1990 1989 1988 0 1987 PATIENTS PMP 16 16,2 19,0 GNI PMP ATHLAS METHOD SOCIO-ECONOMIC INDEXES AND ESRD PREVALENCE R2=0,835 NON PARAMETRICS CORRELATIONS YEAR 2010 p TRR pmp GROSS NATIONAL INCOME 0.000 GROSS NATIONAL INCOME PER CAPITA 0.000 LIFE EXPECTANCY AT BIRTH 0.000 NEPHROLOGISTS PMP 0.659 ARGENTINA: BOLIVIA: Sergio Marinovich Sdenka Maury Fernández José Luis Valencia BRASIL: Jocemir R. Lugon CHILE: Hugo Poblete Badal Ana Mireya Ortiz Susana Elgueta Miranda COLOMBIA: Rafael Gómez COSTA RICA: Manuel Cerdas Calderón Fabio Hernández CUBA: Miguel Almaguer López ECUADOR: Nelly Freire EL SALVADOR: Ricardo Leiva Merino GUATEMALA: Jorge Luna Guerra HONDURAS: Gaspar Rodríguez MEXICO: Guillermo García García Tommaso Bochicchio NICARAGUA : Nubia Cano Norman Iron Danilo Rivas Miranda PANAMÁ: Carlos Viggiano PARAGUAY: Darío Cuevas PERÚ: Carlos Tapia PUERTO RICO: José L. Cangiano REP. DOMINICANA: Sandra Rodríguez URUGUAY: Maria Carlota González Bedat VENEZUELA: Haideé González SOC. DE T LA Y CARIBE: Valter Duro Garcia REGISTRO DE DONACIÓN Y TRASPLANTE DE LA Y CARIBE [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] [email protected] http://www.grupopuntacana.org/ver_pais.php [email protected]