Computed Tomography Radiation Oncology Advancing critical clinical decisions Philips Big Bore RT Pursuit of the successful outcome Radiation therapy can be effective in helping your patients overcome cancer. They depend upon your skills for a successful outcome. However, fragmentation and inefficiencies in radiotherapy processes impact quality of care and make it difficult to provide consistent, accurate, cost-effective and timely treatment. Imaging plays an integral role in the therapy planning Only the most advanced and state-of-the-art solution are critical to enhance delineation of target volume/organs decisions. With Philips, integrated radiation oncology process. Images of sufficient quality for proper contouring at risk and increase accuracy of therapy delivery. Variability in planning workflows can result in inconsistent treatment plans and, subsequently, treatment quality. Maintaining a constant, dependable and reproducible workflow is paramount to answering the increasing demand for cancer services. 2 can address these challenges and advance critical clinical systems and AI‐powered software help radiation oncologists manage complexity and boost efficiencies to accelerate the time from patient referral to treatment. Powerful technology delivers In radiation oncology, successful outcomes are measured by confidently moving patients through the right treatment plans. CT technology can assist by delivering accurate, reliable and reproducible data for treatment planning for your patients. The need for more reliable image information to minimize possible errors in the treatment phase has grown. Philips Big Bore RT is a CT simulator designed and enriched to meet the specific treatment planning and imaging needs of radiation oncology. Philips Big Bore RT Advances confidence in clinical diagnosis and treatment planning Accelerates time to treatment through intuitive workflow tools Enhances patient and staff satisfaction by creating positive experiences Maximizes value with cross-purpose oncology and radiology configuration 3 Advance confidence in clinical diagnosis and treatment planning Big Bore RT is designed to provide precise treatment planning through enhanced accuracy in lesion identification, tissue density calculation and segmentation. Exceptional image quality and the tools to manage and investigate are the foundation for confident decision-making. Enhance accuracy in treatment planning and therapy delivery Big Bore RT utilizes an 80 kW generator and maintains Big Bore RT uses 32 reconstructed slices of data through 60 cm, without approximation of data. The 70 cm visualization in coronal and sagittal images by reducing image quality and Hounsfield Unit accuracy out to extended field of view boosts confidence in visualizing the patient’s entire anatomy in the treatment position. overlapped reconstruction that allow for excellent splay artifacts in images. Expect more from auto-contouring Through low-contrast resolution, low dose with Contour ProtégéAI** pushes the capabilities of auto-contouring iterative model reconstruction (IMR) technology delivers optimized for MIM make contouring quick and efficient high image quality, and virtually noise-free* images, visualization of fine detail and improved clinical accuracy in the detection and delineation of small, subtle structures. 4 forward. Dynamic machine learning methods and algorithms without sacrificing accuracy. * In clinical practice, the use of IMR may reduce CT patient dose depending on the clinical task, patient size, anatomical location and clinical practice. A consultation with a radiologist and a physicist should be made to determine the appropriate dose to obtain diagnostic image quality for the particular clinical task. Low-contrast detectability and noise were assessed using Reference Body Protocol comparing IMR to FBP; measured on 0.8 mm slices, tested on the MITA CT IQ Phantom (CCT183, The Phantom Laboratory), using human observers. ** Offered by MIM Inc. Unveil obscured tissue for more accurate tumor contouring iDose4 improves image quality* through artifact prevention, noise reduction and increased spatial anatomical structure visualization and improves radiation oncologists’ confidence in target delineation. 4D CT with bellows and amplitude binning, included resolution at low dose. in the Pulmonary Tool Kit for Oncology, helps improve O-MAR algorithm can reduce metal artifacts on even in irregular breathers. accuracy in treatment planning and therapy delivery, treatment-planning CT images, which enables better Examine material composition from images Big Bore RT is capable of dual-energy acquisitions. With appropriate calibration, dual-energy data can be used to evaluate stopping power for proton therapy treatment planning. Without IMR With IMR Without O-MAR With O-MAR * Improved image quality is defined by improvements in spatial resolution and/or noise reduction as measured in phantom studies. 5 Simulation made easy Multimodality Sim (MM Sim) is an image simulation platform that supports image fusion and contouring for all available images and data sets. It provides clinical teams with the tools necessary for multimodality image fusion, AI-driven auto-contouring, and efficient collaborations – helping to reduce patient wait time while providing quality care. 6 Decrease Standard Deviations Using CT and MR as compared to CT alone significantly decreased standard deviations by % 60 The highest level of variation was found at the prostatic apex, followed by the prostatic base and seminal vesicles. 1 With MM Sim, CT and MR images reveal clarity and enhance confidence for clinicians through advanced CT/MR image fusion and contouring tools. Modifying contours on either MR or CT images allows modifications to be instantaneously reflected on the other image set. Features a single sign-on patient dashboard accessible from a web browser Offers advanced contour editing, including expansion, retraction and overlapping logic Leverages the Philips experience as an imaging modality company to bring together CT, oblique MR, mDixon, MR Synthetic CT, Spectral CT, SPR, 4D PET/CT, CBCT and 16-bit DICOM images in one platform Generates customized reports and documents Allows for aggregated image and data sets from different vendors on one platform Auto-contouring solutions by MIM Contour ProtegeAI, atlas-based SPICE and Model Based Segmentation to fulfill clinician’s needs in contouring. MM Sim Pro supports 5 and MM Sim Plus supports 2 concurrent so you can add a total of 10 remote clients to allow for access from anywhere. Provides improved 4D CT capabilities and multiplanar respiration motion movie loops In just 10 seconds, MM Sim allows you to run the Navigation Pathways with automation and import AI contours including auto image fusion, optimize user views, set window/level, auto-place the isocenter and add beams. 7 Simulate anywhere Physician places isocenter(s) when patient is on the table. Physician uses MIPs and reviews 4D data to make treatment decisions. Physician may also choose to create emergency and palliative treatment fields. Simulation on CT console (absolute marking, MIPs, 4D reviews, emergency and palliative treatment) Illustrative scenarios Coordinates to lasers Remote location Physician’s office Physician’s second office MIPs and 4D review Absolute marking Relative marking to make treatment decisions while patient is on the table to fiducials when patient is off Physician uses MIPs and 4D data and generate contours when patient is off of the patient table. Physician places isocenter (absolute marking). of the table. Physician creates beam geometry, Physician creates emergency and facilitate dose calculations in the TPS. prepare patient for treatment. treatment fields and contours to 8 Physician adds isocenters relative palliative treatment fields to quickly Accelerate time to treatment through intuitive scan-to-plan workflows Approximately 19.3 million new cancer cases were reported worldwide in 2020 and 28.4 million new cases are expected in 2040, an increase of 47%.2 This significantly drives the demand for cancer services. Our streamlined processes help improve your workflow and throughput. As diagnostic and treatment workloads expand in both Streamline imaging and simulation workflow are under mounting pressure to provide accurate a standardized, patient-centered approach to imaging volume and complexity, radiation therapy departments treatment while minimizing wait times for patients. Today, the radiation oncology planning process can be Philips iPatient dedicated oncology exam cards provide and simulation with consistency from scan to scan. labor-intensive, with frequent handovers, long wait times Expedite to treatment plans workflows and standardizing processes, and providing easy auto-segmentation. Less manual intervention means and lags in data transfers between systems. By optimizing IMR improves image quality and advances access to relevant patient information, Philips supports care fast contouring and short time-to-treatment. teams by integrating clinical workflows, reducing wait times and increasing confidence in decision-making. Without IMR With IMR 9 Enhance patient and staff satisfaction by creating positive experiences A pressing question is how to maintain a patient-centric care experience as the demand for radiation oncology services increases. Our solutions are designed with satisfaction for patients, families and staff in the forefront, enhancing comfort and confidence. Accommodate complex setups easily Patient setup on the Big Bore RT flat table with access to the wide 85 cm bore aperture provides more room to achieve optimal treatment position to facilitate complex procedures. The enhanced design and advanced functionality on the scanner and controls put more at the fingertips of your staff so they can provide your patients with a positive clinical experience. Reduce patient stress during scans Philips Ambient Experience envelops the patient in soothing light and sound, creating a positive distraction that helps reduce patient stress and contributes to a successful imaging experience. Patients become active participants by choosing from an array of room themes. Provide emergency and palliative care treatment “Sim to Treat” tools are designed for speed and efficiency, and allowing you to accelerate time to treatment for emergency and palliative patients. 10 “ User-friendly, fast, and well-functioning virtual simulation software with useful features and tools will be a determining factor for the success of a CT simulation program.” 3 Sasa Mutic, MS Mallinckrodt Institute of Radiology Washington University School of Medicine, St. Louis, MI Accelerate time from referral to treatment “ Increased SFOV allows for full visualization of larger patients and immobilization devices. This feature is important to fully assess patient external dimensions, which are necessary for accurate doses and to monitor unit calculation.” 3 Sasa Mutic, MS Mallinckrodt Institute of Radiology Washington University School of Medicine, St. Louis, MI “ O-MAR-corrected images are more suitable for the entire treatment planning process by offering better anatomical structure visualization and improving radiation oncologists’ confidence in target delineation.” 4 Hua Li Department of Radiation Oncology Washington University School of Medicine, St. Louis, MI 11 Maximize value with a system for both oncology and radiology Flexible upgrades, service options, consulting services and continuous education programs allow you to maximize the value of your investment over the entire lifecycle. Big Bore RT can also provide cross-functional general radiology services, extending its benefits. Big Bore RT can also be used for general radiology services. 12 Empower your teams to deliver Big Bore RT provides enhanced image quality and interventional controls that allow it to be used as a diagnostic scanner for your radiology needs. With Philips Technology Maximizer, you can future-proof Maximize value tailored to your needs as soon as they are released, at a fraction of the cost Service agreement is scalable and customizable, keeping your system and receive software and hardware updates of acquiring them individually. Philips support is designed around you. Every RightFit your equipment up and running, your staff up to speed and your organization on track. • Improved reliability and repeatability of calibrations with harmonized phantoms Philips PerformanceBridge offers a flexible suite of • Windows 10 deployed across the CT system provide a path to help you find and maximize opportunities. • Improved cybersecurity and encryption of patient data continuous performance improvement solutions which Become expert users from the start Our world-class training programs are taught by dosimetrists and therapists who understand the nuances and challenges of patient care that go well beyond scanner features and buttons, so that you may best serve your patients. 13 Advancing radiation oncology imaging for over 25 years 14 Bringing it all together for you and your patients With more than 1,500 Big Bore CT installations worldwide You have a winning combination when you increase and a history of firsts in the radiation oncology space, accuracy in imaging and planning, accelerate time to Big Bore RT helps you address today’s and tomorrow’s treatment, and enhance patient and staff satisfaction, challenges. Integrating tools, systems, software and all while maximizing the value of your investment. service is designed to improve operational efficiency and care delivery. Redefining CT simulation workflow Multimodality simulation (MM Sim) AcQsim CT launched 1991 2000 Legacy pioneered CT simulation Image quality and workflow enhancements for CT Big Bore Oncology 2005 Brilliance CT Big Bore 2011 2016 Big Bore RT 2020 2021 iPatient platform for CT Big Bore AI auto-contouring* *Powered by MIM Contour ProtégéAI 15 1. Villeirs G, et al. Interobserver delineation variation using CT versus combined CT + MRI in intensity-modulated radiotherapy for prostate cancer. Strahlenther Onkol. 2005;181:424–30. 2. Sung H, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021.71:209-249; xdoi.org/10.3322/caac.21660 3. Mutic S. CT Simulation Refresher Course. Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110. www.aapm.org/meetings/2001am/pdf/7200-35328.pdf. 4. Li H, et al. Clinical evaluation of a commercial orthopedic metal artifact reduction tool for CT simulations in radiation therapy. Medical Physics. 2012 Dec;39(12):7507–7517. Philips Big Bore RT is a configuration of Philips CT Big Bore and Big Bore Family. The Philips CT Big Bore is a computed tomography X-ray system intended to produce images of the head and body by computer reconstruction of X-ray transmission data taken at different angles and planes. These devices may include signal analysis and display equipment, patient and equipment supports, components and accessories. These systems are indicated for head and whole-body X-ray computed tomography applications in oncology, vascular and cardiology, for patients of all ages. Note: The above generic description is combination of intended use/indication for use/intended purpose. For more details, please contact your local Philips representative. © 2022 Koninklijke Philips N.V. All rights are reserved. Philips reserves the right to make changes in specifications and/or to discontinue any product at any time without notice or obligation and will not be liable for any consequences resulting from the use of this publication. Trademarks are the property of Koninklijke Philips N.V. or their respective owners. www.philips.com Printed in the Netherlands. 4522 991 78141 * JUL 2022