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Facultad de Medicina
Departamento de Fisiología
FISIOLOGÍA HUMANA
BLOQUE 7. SISTEMA RENAL y EQUILIBRIO HIDROELECTROLÍTICO
Tema 30. Mecanismos de Concentración de la Orina
Dr. Bernardo LÓPEZ‐CANO
Profesor Titular de la Universidad de Murcia
Contenidos
‰Homeostasis hidroelectrolítica
‰Concentración de la Orina
• Vasopresina u Hormona Antidiurética (ADH)
• Sistema de Intercambio por Contracorriente
ƒ Asa de Henle
ƒ Vasos Rectos
‰Papel de la urea en la concentracion de la orina
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Compartimentos Líquidos del Organismo
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Deshidratación Extra e Intracelular
1 Excessive loss of H2O from
ECF
2
ECF osmotic
pressure rises
(a) Mechanism of dehydration
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
3 Cells lose H2O
to ECF by
osmosis; cells
shrink
Hidratación Extra e Intracelular
1
Excessive H2O enters
the ECF
2
ECF osmotic
pressure falls
(b) Mechanism of hypotonic hydration
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
3 H2O moves into
cells by
osmosis; cells
swell
Homeostasis Hidroelectrolítica
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Balance de Agua Corporal
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© 2007
Pearson Education,
Inc., publishing
as Cummings
Benjamin Cummings
Copyright ©
2007 Pearson
Education,
Inc., publishing
as Benjamin
Balance de Agua Corporal
Copyright
© 2007
Pearson Education,
Inc., publishing
as Cummings
Benjamin Cummings
Copyright ©
2007 Pearson
Education,
Inc., publishing
as Benjamin
Osmolaridad de la Orina
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© 2007
Inc., publishing
Copyright
2007 Pearson
Pearson Education,
Education, Inc.,
publishing as
as Benjamin
Benjamin Cummings
Cummings
Neurohipófisis: Vasopresina o ADH
Copyright
Pearson Education,
Inc.,Inc.
publishing
as Benjamin
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©2007
The McGraw-Hill
Companies,
Permission
required Cummings
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Formación de Orina Concentrada o Diluida: Vasopresina o ADH
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
Mecanismo de Acción de la Vasopresina
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© 2007
Inc., publishing
Copyright
2007 Pearson
Pearson Education,
Education, Inc.,
publishing as
as Benjamin
Benjamin Cummings
Cummings
Neurohipófisis: Vasopresina o ADH
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
Factores que Afectan a la Liberación de Vasopresina o ADH
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© 2007
Inc., publishing
Copyright
2007 Pearson
Pearson Education,
Education, Inc.,
publishing as
as Benjamin
Benjamin Cummings
Cummings
Efecto de la Osmolaridad Plasmática sobre la Secreción de Vasopresina o ADH
Copyright
© 2007Education,
Pearson Education,
Inc., publishing
as Cummings
Benjamin Cummings
Copyright ©
2007 Pearson
Inc., publishing
as Benjamin
Efecto de la Osmolaridad Plasmática sobre la Secreción de Vasopresina o ADH
Copyright ©
© 2007
Inc., publishing
Copyright
2007 Pearson
Pearson Education,
Education, Inc.,
publishing as
as Benjamin
Benjamin Cummings
Cummings
Reabsorción Distal de Sodio: Aldosterona
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© 2007
Inc., publishing
Copyright
2007 Pearson
Pearson Education,
Education, Inc.,
publishing as
as Benjamin
Benjamin Cummings
Cummings
Reabsorción Distal de Sodio: Aldosterona
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Mecanismo de Acción de la Aldosterona
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© 2007
Inc., publishing
Copyright
2007 Pearson
Pearson Education,
Education, Inc.,
publishing as
as Benjamin
Benjamin Cummings
Cummings
Sistema Renina‐Angiotensina‐Aldosterona
Copyright
© 2007
Pearson Education,
Inc., publishing
as Cummings
Benjamin Cummings
Copyright ©
2007 Pearson
Education,
Inc., publishing
as Benjamin
Sistema Renina‐Angiotensina‐Aldosterona
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
Sistema Renina‐Angiotensina‐Aldosterona
¶ Volume
Copyright
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Inc., publishing
as Cummings
Benjamin Cummings
Copyright ©
2007 Pearson
Education,
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as Benjamin
Gradiente Osmótico Medular
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Intercambio Contracorriente
Copyright©©2007
2007Pearson
PearsonEducation,
Education,Inc.,
Inc.,publishing
publishingas
asBenjamin
BenjaminCummings
Cummings
Copyright
Intercambio Contracorriente
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Sistema Multiplicador de Contracorriente en el Asa de Henle
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Inc.,Inc.
publishing
as Benjamin
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©2007
The McGraw-Hill
Companies,
Permission
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Intercambio de Contracorriente en los Vasos
Rectos
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Inc.,Inc.
publishing
as Benjamin
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©2007
The McGraw-Hill
Companies,
Permission
required Cummings
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Intercambio de Contracorriente en el Asa de Henle y Vasa Recta
Copyright©©2007
2007Pearson
PearsonEducation,
Education,Inc.,
Inc.,publishing
publishingas
asBenjamin
BenjaminCummings
Cummings
Copyright
Intercambio de Contracorriente en el Asa de Henle y Vasos Rectos
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
Formación de Orina Diluida y Concentrada:
Papel de la Urea
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
Formación de Orina Diluida y Concentrada:
Papel de la Urea
Copyright
Pearson Education,
Inc.,Inc.
publishing
as Benjamin
Copyright ©
©2007
The McGraw-Hill
Companies,
Permission
required Cummings
for reproduction or display
Formación de Orina Concentrada o Diluida: Resumen
http://www.physiol.med.uu.nl/interactivephysiology/ipweb/home/index2.html
ADH
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
Formación de Orina Concentrada o Diluida: Resumen
http://www.physiol.med.uu.nl/interactivephysiology/ipweb/home/index2.html
Mecanismo de Contracorriente
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
Copyright © 2007 Pearson Education, Inc., publishing as Benjamin Cummings
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