Subido por Sebastian Vargas

Informe 1 Bioinformatica Estudio sobre bases de datos de ADN y ARN con Matlab

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Estudio sobre bases de datos de ADN y ARN con
Matlab
F. Nicolas Diaz S, Estudiante (20131273034), Sebastian Vargas V, Estudiante (20131273012).
Universidad Distrital Francisco José de Caldas (Facultad Tecnológica);
Ingeniería en Telecomunicaciones – Bioinformática
Bogotá, Colombia; Septiembre de 2014
Abstract—In this paper we make the study and calculation of
the spectral attenuation coefficients for specific rainfall
intensities according to frequency for circular polarization
Horizontal done.
Cada nucleótido se compone de una base nitrógenada
(purina o pirimidina), un azúcar (D-ribosa o 2-deoxi-Ribosa) y
un ácido Fosfórico. (Figura 1)
Key Words-attenuation, spectrum, polarization.
Index Terms—Component, formatting, style, styling, insert.
(key words)
Resumen—En este documento se hace el estudio de una base de
datos de ADN dos especies de aves diferentes, donde se determina
la densidad y numero de nucleótidos de cada secuencia, se
grafican los resultados; el ADN se traduce a ARN, se observan
sus combinaciones codones en forma de aminoácidos y se llega a
la conclusión que son bastante similares, por lo cual comprueba
que son especies familiares.
Palabras
clave—ADN,
aminoácidos.
ARN,
nucleótidos,
codones,
Figura 1. Base nitrogenada, un azúcar y un ácido fosfórico.
I. INTRODUCCIÓN
Se trabaja con dos aves, la paloma y el águila; cuyos
códigos genéticos ADN han sido descargados por del software
Matlab por medio de la NCBI (National Center for
Biotechnology Information), en forma de base de datos, esta
información viene en forma de secuencia de caracteres
A,T,C,G la cual es procesada en Matlab para determinar la
densidad de nucleótidos, observar la composición del genoma
mitocondrial, hacer la traducción a ARN, ver los codones y
comparar los resultados entre las dos especies.
II. MARCO TEÓRICO
LOS ÁCIDOS NUCLEICOS
Los ácidos nucleicos (ADN y ARN), son macromoléculas
con un número predeterminado de varios monómeros
diferentes en un arreglo ordenado en forma lineal. Los ácidos
nucleicos portan la información genética que determina la
estructura primaria de las proteínas y los fenotipos especieespecíficos.
Cada ácido nucleico contiene un sólo tipo de azúcar, no
ambos. El ADN representa el material genético de las células y
es constituido por nucleótidos conocidos como deoxiribótidos
que contienen 2-deoxi-D-Ribosa.
Los nucleótidos del ADN son Citosina (C), Timina (T),
Guanina (G) y Adenina (A); y los del ARN son Citosina (C),
Uracilo (U), Guanina (G) y Adenina (A).
EL LENGUAJE GENETICO ES COMPLEJO
INTERPRETADO POR VARIOS CÓDIGOS
E
La información genética de la célula se almacena en
secuencias de nucleótidos en los cromosomas. La maquinaria
genética de la célula interpreta secuencias específicas como
señales moleculares y todas constituyen el lenguaje genético.
Señales genéticas controlan la transmisión y expresión de la
información genética, todas las señales son almacenadas en
secuencias de nucleótidos dentro del material genético, pero
pueden funcionar a nivel de ADN, ARN o proteína.
Dada una secuencia de ADN, es posible obtener otra de
ARN representada por los caracteres A, G, C, U; con los cuales
se puede construir la secuencia de aminoácidos de la proteína
resultante de la traducción.
Según el código genético:
Aminoácido
Codones
Alanina
Ala A
GC(ACGU)
Arginina
Arg R
CG(ACGU) o AG (AG)
Asparragina Asn N
AA(CU)
Aspartato
Asp D
GA(CU)
Cisteìna
Cys C
UG(CU)
Glutamato Glu E
GA(AG)
Glutamina Gln Q
CA(AG)
Glicina
Gly G
GG(ACGU)
Histidina
His H
CA(CU)
Isoleucina
Ile
I
UA(AG) o UGA
Leucina
Leu L
CA(ACGU) o UU(AG)
Lisina
Lys K
AA(AG)
Metionina Met M
AUG(inicio de síntesis)
Fenilalanina Phe F
UU(CU)
Prolina
Pro P
CC(ACGU)
Serina
Ser S
UC(ACGU) o AG(CU)
Treonina
Thr T
AC(ACGU)
TRiptòfano Trp W
UGG
Tirosina
Tyr Y
UA(CU)
Valina
Val V
GU(ACGU)
Nota: GC(ACGU )= GCA, GCC, GCG, GCU.
Tabla 1. Traducción de código genético.
III. PROCEDIMIENTO
Se carga la base de datos de mitocondrias de la NCBI de
dos especies, se hallan las gráficas de densidad de nucleótidos
a lo largo de la secuencia, ver el número de nucleótidos en la
secuencia, se traduce la secuencia ADN a ARN para lograr la
secuencia de aminoácidos de la proteína correspondiente.
Se inicia el proceso con el Aguila utilizando Matlab para
bajar y acceder a la base de datos del ADN, se genera la gráfica
de densidad de nucleotidos, se convierte de ADN a ARN, se
muestra la distribución de las bases y los aminoacidos
presentes.
Se sigue el siguiente diagrama de flujo para obtener toda la
información:
Codigo en Matlab:
%ADN AGUILA
clc
clear
Aguila = getgenbank('NC_024087','SequenceOnly',true)
%Leer Secuencia
ntdensity(Aguila)
%La densidad de Nucleotidos dentro de la secuencia de ADN
basecount(Aguila)
%Informacion de los nucleotidos en la secuencia
basecount(seqrcomplement(Aguila))
%inverso de la funcion anterior
figure
dimercount(Aguila,'chart','bar')%Nucleotidos Adyacentes
%Se convierte de ADN-ARN
ARN_Aguila = dna2rna(Aguila)
%Convierte el valor de ADN-ARN
amino = nt2aa(Aguila)
%Toma la secuencia y lo convierte a aminoacidos
aminoacidos = aacount(amino)
%Cuenta la cantidad de aminoacidos de la secuencia
figure
basecount(Aguila,'chart','pie')
%Distribucion de las Bases
codoncount(Aguila)
IV. RESULTADOS
Las secuencias de ADN obtenida a través de Matlab son
demasiado extensas y se muestra en el Anexo 1 para el águila y
en el Anexo 2 para el trepador pechiblanco.
Figura 2. Imagen de un Aguila.
Figura 5. Densidad de nucleótidos del trepador pechiblanco.
NUCLEOTIDOS
Figura 3. Trepador pechiblanco.
GRAFICA DE DENSIDAD DE LOS NUCLEÓTIDOS
Figura 4. Densidad de nucleótidos del águila.
AGUILA:
Se hace el conteo de los nucleótidos dentro de la secuencia
del ADN
A: 5153; C: 5657; G: 2431; T: 4091
Se realiza el conteo inverso de la cantidad de nucleótidos
para formar los pares.
A: 4091; C: 2431; G: 5657; T: 5153
Figura 6. Torta de porcentaje de cantidad de nucleotidos para el
aguila.
TREPADOR PECHIBLANCO:
Se hace el conteo de los nucleótidos dentro de la secuencia
del ADN
A: 5220; C: 5221; G: 2388; T: 3997
Se realiza el conteo inverso de la cantidad de nucleótidos
para formar los pares.
A: 3997; C: 2388; G: 5221; T: 5220
Figura 8. Diagrama de barras dimeros para el aguila.
TREPADOR PECHIBLANCO
Hace el conteo de los dímeros y los representa en un
diagrama de barras.
Figura 7. Torta de porcentaje de cantidad de nucleotidos para el
trepador pechiblanco.
AA: 1608;
CA: 1560;
GA: 734;
TA: 1318;
AC: 1497; AG: 927; AT: 1188;
CC: 1760; CG: 461; CT: 1440;
GC: 733;
GG: 465;
GT: 456;
TC: 1231;
TG: 534;
TT: 913
OBSERVACION
Se resalta que la densidad de los nucleótidos varía bastante
entre las dos especies; Pero al observar la densidad de AT y
CG se observa una simetría similar en las dos aves, se puede
deducir que tienen de codificaciones de ADN similares, y
entonces serian familiares.
DIMEROS
AGUILA
Hace el conteo de los dímeros y los representa en un diagrama
de barras.
AA: 1601; AC: 1546; AG: 840; AT: 1165;
CA: 1583; CC: 1974; CG: 497; CT: 1603;
GA: 686;
GC: 804;
GG: 511; GT: 430;
TA: 1282; TC: 1333; TG: 583; TT: 893.
Figura 9. Diagrama de barras dimeros para trepador pechiblanco.
AMINOACIDOS
Se hace la traducción de ADN a ARN y se obtienen los
aminoácidos.
A demás hace el conteo de esos aminoácidos, estos se deben
interpretar con la tabla 1.
AGUILA
A: 208;
Q: 239;
L: 611;
S: 676;
R: 293; N: 330;
E: 117; G: 141;
K: 244; M: 68;
T: 510; W: 42;
D: 107;
H: 342;
F: 125;
Y: 224;
C: 91;
I: 282;
P: 701;
V: 114
CODONES.
Se cuentan los codones de la secuencia de nucleótidos.
AAA - 158 AAC - 196 AAG - 86 AAT - 134
ACA - 125 ACC - 156 ACG - 51 ACT - 178
AGA - 63 AGC - 131 AGG - 62 AGT - 57
ATA - 85 ATC - 110 ATG - 68 ATT - 87
CAA - 151 CAC - 166 CAG - 88 CAT - 176
CCA - 176 CCC - 210 CCG - 67 CCT - 248
CGA - 39 CGC - 65 CGG - 31 CGT - 33
CTA - 138 CTC - 154 CTG - 81 CTT - 110
GAA - 65 GAC - 58 GAG - 52 GAT - 49
GCA - 68 GCC - 67 GCG - 21 GCT - 52
GGA - 36 GGC - 45 GGG - 35 GGT - 25
GTA - 37 GTC - 26 GTG - 27 GTT - 24
TAA - 156 TAC - 133 TAG - 107 TAT - 91
TCA - 116 TCC - 166 TCG - 71 TCT - 135
TGA - 49 TGC - 64 TGG - 42 TGT - 27
TTA - 77 TTC - 70 TTG - 51 TTT - 55
TREPADOR PECHIBLANCO
A: 267;
Q: 275;
L: 601;
S: 581;
R: 282;
E: 122;
K: 244;
T: 460;
N: 250; D: 117; C: 78;
G: 169; H: 262; I: 312;
M: 57; F: 189;
P: 591;
W: 30; Y: 238;
V: 173
CODONES.
Se cuentan los codones de la secuencia de nucleótidos.
AAA - 160 AAC - 140 AAG - 84
ACA - 153 ACC - 154 ACG - 33
AGA - 69 AGC - 99 AGG - 66
ATA - 97 ATC - 116 ATG - 57
CAA - 190 CAC - 141 CAG - 85
CCA - 191 CCC - 178 CCG - 55
CGA - 54 CGC - 34 CGG - 28
CTA - 198 CTC - 125 CTG - 58
GAA - 79 GAC - 72 GAG - 43
GCA - 82 GCC - 116 GCG - 15
GGA - 72 GGC - 40 GGG - 24
GTA - 63 GTC - 52 GTG - 16
TAA - 149 TAC - 140 TAG - 88
TCA - 145 TCC - 140 TCG - 43
TGA - 73 TGC - 52 TGG - 30
TTA - 90 TTC - 120 TTG - 32
AAT - 110
ACT - 120
AGT - 52
ATT - 99
CAT - 121
CCT - 167
CGT - 31
CTT - 98
GAT - 45
GCT - 54
GGT - 33
GTT - 42
TAT - 98
TCT - 102
TGT - 26
TTT - 69
CONCLUSIONES


Para seres vivos de la misma especie, cuya base de
datos de ADN sea analizada se observara que el
número de nucleótidos es muy similar, al igual
que los aminoácidos presentes en cada uno.
Se puede hacer el estudio de ADN y ARN para
determinar los aminoácidos que caracterizan a un
ser vivo, y posteriormente será útil para para
determinar las proteínas que constituyen a dicho
ser vivo.
REFERENCIAS
[1] ROBERTO P. DIAZ Curso virtual “Biologia Computacional”,
Universidad
Nacional de Colombia
Sede
Bogota.
http://www.virtual.unal.edu.co/cursos/ingenieria/2001832/docs_
curso/contenido.html
[2] Matlab aplicado a la bioinformática Toolbox de bioinformática:
entorno de software integrado para el genoma y análisis
proteómico - Jairo Pertuz Camp;
[3] MATLAB 7.1, Release 14 Service Pack 3, The
MathWorks Inc.; Bioinformatics Toolbox 2.1.1. The
MathWorks Inc; Bioinformatics Toolbox For Use with
MATLAB, User Guide, V. 21.1, The MathWorks Inc.
2005.
ANEXO 1. Secuencia de AND, ARN Y AMINOACIDOS del Aguila
ADN Aguila
AACTAATGGCCCCCAATCCCCGAAAGTCCCACCCCCTACTAAAAATAGTCAATAACTCCCTAATCGACCTCCCCACCCCCTCAAACATCTCTACTTGATGAAACTTCGGCTCCCTCCTAGGAATCTGC
CTAATAACACAAATCCTAACCGGCCTCCTATTAGCCATACACTACACCGCAGACACCACCCTAGCCTTCTCATCCGTCGCCCACACATGTCGGAACGTACAGTACGGCTGACTAATCCGCAACCTAC
ATGCCAACGGAGCATCCTTCTTCTTCATCTGCATTTACCTTCACATCGGCCGAGGACTCTACTACGGCTCATACCTTTATAAAGAGACCTGAAACACAGGAATCATTCTCCTACTTACCCTTATAGCA
ACCGCCTTTGTAGGCTATGTCCTCCCATGAGGACAGATATCCTTCTGAGGAGCCACAGTCATCACCAACCTATTCTCAGCAATCCCATACATCGGACAAACCCTCGTAGAGTGGGCCTGAGGTGGAT
TCTCTGTAGATAACCCCACCCTCACTCGCTTCTTCGCCCTACATTTTTTACTTCCATTCCTTATCGCAAGCCTTACCCTAATCCACCTTACCTTCCTACACGAGTCCGGATCAAACAATCCCCTAGGAAT
TATCTCAAACTGTGACAAAATCCCATTCCACCCCTACTTCTCCCTAAAAGACATCCTAGGATTCGTACTAATACTACTCCCACTAACAACTCTAGCTCTATTCTCACCTAACCTGCTAGGCGACCCAG
AAAACTTCACCCCAGCAAACCCCCTAGTTACACCCCCTCATATCAAACCAGAATGATACTTCCTATTTGCATACGCCATCCTACGTTCAATCCCAAACAAGCTGGGAGGAGTGCTAGCTCTAGCTGCC
TCAGTACTGATCCTATTCCTTATCCCCTTCCTCCATAAGTCCAAACAACGCACAATAACCTTTCGACCCCTCTCCCAACTCCTATTCTGGACCCTAATCGCCAACCTCCTCATCCTCACATGGATTGGC
AGCCAACCAGTAGAACACCCGTTCATTATCATCGGCCAACTCGCCTCCCTCACCTACTTCTCCACCCTCCTAATCCTCTTCCCTCTAATTGGAGCCCTCGAAAATAAAATGCTCAACCACTAAAAATA
CTCTAATAGTTTATAAAAAACATTGGTCTTGTAAACCAAAGACTGAAGACTATCCCCCTTCTTAGAGTTACCCGGCCCGAAAGGGCCATTATTGCCAAATTTTATTTAAAACTCCCCTAGCAACGTAA
TACAGGCGGCCCCCCCCCTCCCCCCCGTATGTACTATTGTACATTCAACCATTTACCGCATATCATGCACCATTCATATGTATACATATTAATGAATGTACTACGTTCATATACATGTAATACGGGCAT
ACATCTCTTTGGGCCATCTCTACTTTCAGGTACGGGTTTCACTTAATGAACTCCTAGATTGTCCTCGATCTCCCCCCGGGCTAGATACATACCAGAGGTGGTTCTCTGTGTAGAACTTGGTCTTCCCTA
CGGATATTCTTGGGGACAAACTCTGCATGGTAGCAGGTCATAACTTGCAATCCTCTCTCGTCGGACCGGTAGCTGTCGGACCAGGTTATTTATTGATCGGGCTCCTCACGAGAAATCAGCAACCTTAC
GGTGGTAGTAAGATCCTACGTTACTAGCTTCAGGACCATTCTTTCCCCCTACACCCCTCGCACTACTTGCACTTTTGCGCCTCTGGTTCCTATGTCAGGGCCACGACTTGGTTAGTCCTACGACCTTGC
TCTTTACGAATACATCTGGTTGGCTATTGATCACCATTCTGCCTCTTAATCGCGGCATCCGGGTGGTTCTCTACTGTTGGTTCCCTTTTTTTTTTTGGGGTAACTTCACAGGTGGCCCTCATATATGCAC
CGCGGCTCATACAATCTAAGACGTGGGCCCTCCTGGCCCTCGGCCAGTCCTCGATCTCAAGAGTTGATTAATGAGACGGTTTCAAGTATCCGGGGAATCATTTTGACACTGTGCACTGGTCAGGAGC
ATCTGGCTATGGCGTGTCCACAGACCCTACTCATGGTGCTATTTGGTGAATGCTTGTGGGACATGATTTTATATTTTTTCTTTCCTCTGACTTTCTAAGTATCACTAGGCGTTTCTAACTAAAACGCTA
ACCGTGTTTTTTCACAAATTTTTTTCACTTTTTTTCACATTTTTTCACATTTTTTTCATTCGTTAAAGGCACTGAGGTTCCATTAATAAATCAAACCATTTCATTCATCATTTTATTCTTGTCATTCATCAA
ATTTTTTCACAAAATCACCCCAAACAACCTCTAAAAATCCATTAATAATCATTTCATCAACAAACTTCAGAAAAAAAGGGCTCAAACCTCTATCACCAACTCCCAAAGCTGGTATTTTACATTAAACT
ATTCTCTGACATCCTTCCCCCCTAAACTGCCCGAATCGCCCCACAAGATAACCCACGTACAAGCTCCAACACAACAAACAACGTCAACAACAACCCTCACCCCGCTGCCAAAAACATTCCTACCCCC
CACGAATAAAACATAGCAACCCCACTAAAATCCAACCGAGCCACAAAGACACCCCCCTCATCAACAGTAACCACACCAATCTTTCAACATTCAACCCCGCTGACAACTACTCCTACAACAAGCGCC
AAAACCATTCCCACTCCATACCCCAAAACCCGCCAATCCCCCCATGCCTCCGGAAAAGGATCCGCCGCTAAACACACCGAGTAGACAAAGACTACTAACATTCCACCCAAGTACACCATAAACAAC
ACTAAAGCTACAAACGGCACCCCCAAACTTACCAACCACCCACACCCTACAACAGACCCTAACACCAACCCAACAACCCCATAATAAGGTGACGGATTAGATGCAACTGCAAGCCCCCCTAGAACA
AACCCCGCCCCCAAAAGAAGAACAAAATAAGCCATTATAATTTCTGCTTGGCTTCTCTCCAAAATCTACGACCTGAAAAATCGTCGTTGTAAACTTCAACTACAGAAACCTAGCAAATACTCCCACC
CAGCCTCCCCCTTAAACTCTAAATAATCTGCGCACTAAGTCCCACTATTCACCCCGCCTTCTATCCTAAGCAACACATTCAACACCCGCACCACATCCACAACAAACATACCCCCATTTCACCTCCAA
GCCCCCACTTTCAAGACCAGGCTTCACAACACATACAATCTAAACCAAGAACACTCCTACCTTCAATCAACACCCAATCCCAAAATCCACTAACGAAACGGTTTCAAGTATCCAAAAACACCAAAAC
ACTAACCACGTTTTTCACGTATTTTTTCACATTTTTCACTTTCACATTTTTTTGTTCACCAAAAGCACTGGAGTCTCATTAATTTTTTCAAATCACATATCTCATATTTTATTTGTGTGTACACT AAACAC
ACCAAAATATTAAAGAGACCCCCCTACTGAATACACCAAACACATAACACCACCACGCACCAACCCACAAACAGCAAGCATACACAAGCTCAACCAACAATATAAATGAATGATTAGTTCTAATAG
AGCCGTGAACAAATAACCAACAATATAAATGAATGATTAGTTCTAATAGAGCCGTGAACAAATAACCAACAATATAAATGAATGATTAGTTCTAATAGAGCCGTGAACTTATAACAAAGCATGGCA
CTGAAGATGCCAAGATGGCTACCGACCATAGCCCGTGGACAAAAGACTTAGTCCTAACCTTACTGTTAACTCGTGCCAAATATATACATGCAAGTATCTGCGTCCCAGTGTAAATGCCCTTGATTCCT
TACTAAGACGACAGGAGCAGGTATCAGGCACACCCGCTCAACCGTAGCCCAAGACGCCTAGCTCAGCCACACCCCCACGGGTACTCAGCAGTAATTAACATTAAGCAATAAGTGTAAACTTGACTT
AGTTATGGCACTCTTAGGGTTGGTAAATCTTGTGCCAGCCACCGCGGTCATACAAGAGACCCAAGTTAACAGTTGTCCGGCGTAAAGAGCGGGCACCTGCTATCTAAGCAGCTGGGATTAAACCACG
GCTAAGCTGTCATAAGCCCAAGGCGTGTTTAAAGCCATCCCCAAGGCGATCCCAACGCCCACGACCAACCAAACCCCGCGAAAGCCAGGGCACAAACTGGGATTAGATACCCCACTATGCCTGGCC
CTAAATCTTAATACTTCCCCCACTAAAGTATTCGCCCGAGTACTACGAGCACAAACGCTTAAAACTCTAAGGACTTGGCGGTGCCCCATACCCACCTAGAGGAGCCTGTTCTGTAATCGATAACCCA
CGCTACACCCCACCACTCCTAGCCCGGACAGCCTACATACCGCCGTCGCCAGCTCACCTCCCTGAGAGACCAACAGTGAGCCAAATAGCCCCACCCGCTAAAAAGACAGGTCAAGGTATAGCCCAC
GGAGTGGAAGAAATGGGCTACATTTTCTAAAGTAGAAAATCACACGGAAGGGGGCGTGAAACAGCCCCTGGAAGGCGGATTTAGCAGTAAAGTGGGACAATAAAGCCCTACTTAAGCCGGCCCTG
AGGCACGTACATACCGCCCGTCACCCTCCTCGCAAGCCATAACCCATCTATAACTAATAACCCAACTAGCTGAAGATGAGGTAAGTCGTAACAAGGTAAGTGTACCGGAAGGTGCACTTAGCATAC
CAGGGCGTAGCTATAATGTAAAGCATTCAGCTTACACCTGAAAGATACCTACCACCGCCTAGGTCGCCCTGAAGCCAAGCTCTAGCCCACACACCCCAACAAGCCAAAACCCATTTTACCCACAAAC
TAAAGCATTCTCTTAACTTAGTATAGGCGATAGAAAAGTTTTCCCCTGGCGCGATAGAGATCCGTACCGTAAGGGAAAGATGAAATAACAATGAAACCCCAAGCAGCATACAGCAAAGATAAATCC
TTGTACCTCTTGCATCATGATTTAGCAAGAATAACCAAGCAAAACGAATTTGAGCTTGCCTCCCCGAAACCTGAGCGAGCTACCTATAGGCAGCTGCCCCGAGCGAACCCGTCTCTGTTGCAAAAGA
GTGGGATGACCTATTGGTAGTGGTGAAAAGCCAATCGAGCTGGGTGATAGCTGGTTGCCTGTGAAACGAATCTAAGTTCTTCCTTAGTTCCTCTCCACGGATCCGTAGCCGAACCCTCACGTAGTGA
ACTAAGAGTAACTTAAAGGAGGTACAGCTCCTTTAAGAAAGAACACAATCTCTCATAGCGGATAACATAACTTACCACTCCCCCGTAGGCCTTCGAGCAGCCATCGACAAAGAATGCGTCAAAGCT
CCCTCCCCTAAAAATGTGAAAACAACATGACCCCCTCCCCACTAACAGGCTAACCTATCACAATAGGAGAATTAATGCTAGAATGAGTAACTAGGGCTTCCCCCTCTTAAGCGCAAGCTTACATCAC
CCCATTATTAACAGCATCTAAATAATATTCTAATCTCAACAAGTCAGTATATTTAAAATTACTCTGTTAACCCGACCCAGGAGCGCCCACTAGAAAGACTAAAATCTGCAAAAGGAACTAGGCAACC
CCAAGACCCGACTGTTTACCAAAAACATAGCCCTCAGCAAACCAAGTATTGAAGGTGATGCCTGCCCAGTGACCCTTAGTTCAACGGCCGCGGTATCCTAACCGTGCGAAGGTAGCGCAATCAATTG
TCCCATAAATCGGGACTTGTATGAATGGCTAAACGAGGCCTTAACTGTCTCTTGCAGATAGTCCGTGAAATTGATCTTCCTGTGCAAAAGCAGGGATGAGCACATAAGACGAGAAGACCCTGTGGA
ACTTAAAAATCAACAGCCACCACATATAACTACACACCTACTAGGCTCACAACCAAAATTAAGTCCTGGTCTGCATTTTTCGGTTGGGGCGACCTTGGAGAAAAGAAAAACCTCCAAAAATAAGAC
CACACCTCTTAACCAAGAGCAACTTCTCAACGTACCAACAGTAACCAGACCCAATAACAATTGATCAATGGACCAAGCTACCCCAGGGATAACAGCGCAATCCCTCCCAAGAGCTCCTATCGACGG
AGGGGCTTACGACCTCGATGTTGGATCAGGACATCCTAATGGTGCAGTCGCTATTAAGGGTTCGTTTGTTCAACGATTAACAGTCCTACGTGATCTGAGTTCAGACCGGAGCAATCCAGGTCGGTTTC
TATCTATGCAGCACTTTCCCTAGTACGAAAGGACCGGGAAAGTAAGGCCAATACCACAAGCATGCCTTCTCCCTAAATAATGACCTCAACTAAACTATAAAAGGAACCCCCACTTACCTCCCAAGCC
CTAGAAAAGGGCCGCTAGCGTGGCAGAGCCCGGTAAATGCAGAAGGCTTAAGCCCTTTACCCAGAGGTTCAAGTCCTCTCTCTAGCCCTACCCACAATGACCCGTCCCTCTATCCTAACTCACCTTG
CCATAGCCCTATCCTACGCAATCCCCATCCTAATCGCCGTAGCCTTCCTAACACTAGTAGAACGAAAAATCCTAAGCTACATACAAGCTCGGAAAGGTCCAAACATTGTTGGGCCCTTCGGACTACT
ACAGCCCGTAGCTGATGGCGTGAAACTATTTATCAAGGAACCAATCCGCCCCTCTACCTCCTCTCCCCTCCTCTTCACCATAACGCCCATGCTAGCCCTCCTCCTAGCATTAACCATTTGAATTCCCCT
TCCCCTCCCCTTTCCCCTTGCTGACCTAAACCTAGGACTACTCTTCCTCCTAGCAATATCTAGCCTAGCAGTCTACTCAATCCTGTGATCTGGATGAGCCTCAAATTCAAAATATGCATTAATTGGAGC
CCTCCGGGCAGTAGCACAGACCATCTCTTACGAAGTCACACTCGCCATCATTCTCCTATCCGTAATTCTTCTGAGCGGGAACTACACCCTGCACACGCTCACTACCACTCAAGAACCTCTCTACCTCA
TCTTCTCATCCTGGCCCCTCACAATAATATGATATATCTCCACACTAGCCGAGACAAACCGAGCCCCCTTCGACCTCACAGAAGGAGAATCCGAGTTAGTTTCAGGCTTTAACGTAGAATATGCCGC
AGGACCATTTGCCCTATTCTTCCTTGCCGAATACGCAAACATTATACTAATAAACACACTAACCACAATTCTATTCCTAAACCCCAGCTCACTTAACCTGTCCCCCCAACTATTTACAGTAGCCTTAGC
AACGAAAATTCTGCTCCTCTCCTCTGGATTCCTATGAATTCGCGCCTCATACCCACGCTTCCGCTACGACCAACTCATGCACCTTCTCTGAAAAAATTTCCTACCCTTGACACTAGCACTATGCCTCTG
GCACATTAGCATACCAACCTGCTACGCAGGAGTACCTCCTTGCTTAAGGAAATGTGCCTGAACGCAAAGGGTCACTATGATAAAGTGAACATAGAGGTATACCAACCCTCTCATTTCCTAAGACCTT
GAACCCTAGAAAAGCAGGAATCGAACCTACACAGAAGGGATCAAAACCCTCCATACTTCCTTTATATTATTTCCTAGCAGGGTCAGCTAATAAAGCTATCGGGCCCATACCCCGAAAATGATGGTTC
AACCCCTTCCTCTGCTAATGAACCCCCACACAAAATTACTCTCCTTCCTAAGCCTAATCCTAGGCACAACCATTACAATCTCAAGCACCCACTGAGTAATGGCCTGAACCGGACTAGAACTCAACAC
CCTCGCTATCATCCCATTCATTTCAAAATCCCACCATCCCCGAGCCATCGAAGCTACAATCAAGTACTTCCTAGTACAAGCAACAGCCTCAACCCTCCTCCTATTCTCAAGCATAACAAACGCATGAT
CTACTGGCCAATGAGATATCACACAACTAACTCACCCCACCTCCTCCCTATTACTGACAGTAGCAATTGCAATAAAACTAGGACTAGTACCTTTCCACTTCTGATTCCCAGAAGTACTACAAGGCTCA
TCCCTAACTACTGCCCTACTTCTCTCCACAATAATAAAACTCCCCCCAACTGCTCTCCTCTTTCTAACCTCTCACTCACTCAATCCTACACTACTAACCGCCATAGCCATCGCCTCCGTAGCCCTAGGA
GGATGAATGGGCCTAAACCAAACACAACTCCGAAAAATTCTGGCCTTTTCATCCATCGCCCACCTAGGATGGCTAACCGCAGTCATCATCTACAACCCTGAACTCGCCCTACTAACTTTCTACTTATA
TATCCTAATAACCACTACTGTATTCCTCACCCTCAACTCAACCAAAACCCTAAAGCTAACAACCCTAATAACATCATGAACAAAATCCCCTACACTAAACGCAACCCTCATACTAGTTCTACTCTCCC
TAGCAGGGCTTCCCCCACTAACAGGCTTCCTACCCAAATGACTCATCATCCAAGAACTAACCAAACAAGAAATAGCCTCAACAGCCACAATCATTGCTACCCTCTCCCTCCTAGGACTATTCTTTTAC
CTCCGTCTCGCATACCACTCAACAATTACACTACCACCCAACTCTACAAACCACATAAAACTATGGCACCTTACCAAGCCGACAAGTACCACAATCGCCGCCCTCGCCGCCCTATCAGTATTAACCTT
ACCGCTCTCCCCTCTAATCCTGACTACCACCTAGAAACTTAGGATAACTGATAAACCGAAGGCCTTCAAAGCCTTAAATAAGAGTTAAACCCTCTTAGTTTCTGCTAAGATCCGCAGGACACTACCCT
GCAACCCCTGAATGCAACTCAGATACTTTAATTAAGCTAGGACCTTACCTAGATAGATGGGCCTCGATCCCATAAAACCCTAGTTAACAGCTAGGTGCCCTAACCAGTGAGCTTCTACCTACCAGAC
CCTGGCACGTCCTTAACGCACATCAATGAGTTTGCAACTCACTATGAACTTCACTACAAGGTCGATAAGAAAGGGAATTAAACCCCTGTAAAAAGGACTACAGCCTAACGCTTAAACACTCAGCCAT
CTTACCTGTGACACTTATCAATCGATGACTATTCTCAACCAACCACAAAGACATCGGCACTCTATACCTAATCTTCGGCGCATGGGCTGGCATAGTCGGCACCGCCCTTAGCCTTCTTATCCGCGCAG
AACTTGGCCAACCTGGCACCCTCTTAGGCGATGACCAAATCTACAATGTAATCGTCACCGCTCATGCTTTCGTAATAATCTTCTTCATAGTCATACCAATCATAATTGGAGGCTTTGGAAACTGACTT
GTCCCACTCATAATTGGCGCCCCCGACATAGCCTTCCCACGCATAAACAACATGAGCTTCTGATTACTCCCCCCATCCTTCCTCCTCCTACTAGCCTCTTCAACAGTAGAAGCAGGGGCTGGCACCGG
GTGGACTGTCTACCCCCCACTAGCCGGCAACATAGCCCACGCCGGCGCTTCGGTAGACCTAGCTATCTTTTCCCTCCATCTAGCAGGTATCTCATCCATCTTAGGGGCCATTAACTTTATCACAACAG
CCATTAACATAAAACCCCCAGCCCTCTCCCAATACCAAACACCCCTATTCGTATGATCCGTTCTTATTACCGCTGTCCTACTATTACTCTCACTCCCCGTCCTAGCTGCTGGCATCACTATATTACTTA
CAGACCGAAACCTCAACACAACATTCTTCGACCCCGCTGGCGGCGGTGACCCAATTCTGTACCAACACCTCTTCTGATTCTTCGGACACCCCGAAGTCTACATCCTAATTCTCCCAGGCTTTGGGATC
ATCTCCCACGTAGTAACATATTACGCAGGCAAAAAAGAGCCATTTGGCTACATAGGAATAGTCTGAGCCATACTCTCCATCGGATTCCTAGGCTTCATCGTATGAGCCCACCATATATTCACAGTAG
GAATAGACGTAGACACCCGAGCATACTTCACATCTGCCACTATAATCATCGCTATTCCGACCGGTATTAAAGTATTCAGCTGACTGGCAACACTACATGGAGGGACTATCAAATGAGACCCGCCCAT
ACTATGAGCCCTAGGCTTCATCTTCCTCTTCACCATCGGAGGCCTAACCGGGATCGTCCTAGCGAACTCCTCACTAGACATCGCCCTGCACGATACATACTACGTAGTTGCCCACTTCCACTATGTCC
TCTCAATAGGAGCCGTCTTCGCCATCCTAGCAGGATTCACTCACTGATTCCCCCTACTAACAGGATTCACCCTACACCCCACATGAGCCAAAGCACATTTTGGGGTTATATTCACAGGAGTAAACCTA
ACCTTCTTCCCACAGCACTTCTTAGGCCTTGCCGGAATACCCCGACGGTACTCAGACTACCCAGATGCCTACACCCTATGAAACACCATGTCCTCTATCGGCTCACTAATCTCAATAACGGCCGTAAT
TATGCTAATATTCATTATCTGAGAAGCCTTCGCCTCAAAACGAAAAGTCCCACAACCAGATTTAACTACAACCAACGTTGAATGAATCCACGGCTGCCCACCTCCATACCACACCTTCGAAGAACCA
GCCTTCGTCCAAGTACAAGAAAGGAAGGAATCGAACCCTCGTACACTGGTTTCAAGCCAGCCGCATCTAACCACCTATGCTTCTTTCTTCCCATGGGATGTTAGTAAAACAATTACCTAATCTTGTCA
AGATTAAATCACAGGTGAAAATCCTGTACACCCCACCATGGCCAACCACTCACAATTTGGATTCCAAGACGCCTCGTCACCCATCATAGAAGAACTCGTCGAATTCCACGATCACGCCCTAATAGTT
GCACTAGCCATCTGCAGCCTAGTCCTATACCTCCTAGCACTTATACTAATAGAAAAACTATCCTCAAACACTGTAGACGCCCAAGAAATCGAACTAATCTGAACAATCCTACCAGCCATCGTCCTCA
TCATACTTGCCCTCCCATCCTTACAAATCCTATACATAACAGATGAAATCAACGAACCAGATCTCACACTAAAGGCCATCGGCCACCAATGATACTGAACCTACGAGTACACAGACTTTAAAGACCT
AACATTCGACTCCTACATAATTCCAACAACAGATCTTCCACCAGGACACTTCCGACTACTCGAAGTTGACCATCGCGTAGTCATCCCAATAGAATCTCCCATCCGCATCATCGTCACAGCCAACGATG
TCCTCCATGCCTGAGCAGTCCCCGCACTGGGTGTAAAAACTGATGCAATCCCAGGGCGACTAAACCAAACATCATTCATCACAACCCGGCCTGGGGTCTTCTACGGCCAATGTTCAGAAATCTGTGG
AGCTAACCACAGCTACATGCCAATCGTAGTAGAATCAACCCCCCTAACCCACTTCGAACACTGATCATCACTCATATCCTCCTAATCATTAAGAAGCTATGCAACAGCACTAGCCTTTTAAGCTAGA
GAAAGAGGACCATCCGTCCCTCCTTAATGATATGCCACAACTTAACCCAGCCCCATGACTCCTCATCATACTAGCATCATGACTAACCCTCACACTAATCGTTCAACCCAAACTCTTATTCTTTACCT
CCACTAACATCCTACCCAACAAACCCATTACAACTATCAACCTCTCCCCCTGAAACTGACCATGATCCTAAACTTCTTCGACCAATTCACAAGCCCCTGCCTCTTAGGCATCCCACTTATCCTAATTTC
AATGCTATTCCCCACCTTATTACTTCCCTCACCAACCAACCGATGAATTACCAACCGCCTCTCCGCACTCCAACTATGATTCATCCACCTAGTCACAAAACAACTAATACTACCCCTAAATAAAGGAG
GACATAAATGGGCTCTAATCTTAGTATCACTAATAACTCTCCTACTAACAATCAACTTACTAGGATTACTGCCATACACATTCACCCCAACCACCCAACTATCAATAAACATAGCCCTTGCCTTCCCC
CTCTGACTAGCTACCCTCCTTACAGGCCTACGGAACCAGCCCACAGCATCCCTAGGTCACCTTCTACCCGAAGGCACTCCAACACCACTAGTTCCTGCCTTAATCCTAATCGAAACTATCAGCCTACT
CATTCGCCCCCTAGCCCTAGGTGTCCGCCTAACAGCAAACTTAACAGCAGGCCACCTACTAATCCAACTCATCTCCACCGCTACTACTACTCTGCTCCCCATCCTCCCAACAGTATCTGCTCTAACCG
CACTAATCCTGCTACTACTGACTATCCTAGAAATTGCAGTAGCCATAATCCAAGCCTACGTCTTCGTCCTACTCCTAAGCCTATACCTGCAGGAAAACATCTAATGGCCCACCAAGCACATTCCTACC
ACATAGTAGACCCTAGCCCCTGACCTATCTTCGGCGCTGCAGCTGCCCTGCTCACTACATCCGGACTCATCATATGATTCCATCACAACTCCTCTCAACTCCTGTCCATAGGCATTCTCTCCATACTTT
TAGTCATACTACAATGATGACGAGACATTGTACGAGAAAGCACATTCCAAGGCCACCACACCCCCACTGTCCAAAAAGGCCTGCGATATGGAATAATCCTATTCATCACATCCGAAGCATTCTTCTT
CCTTGGCTTCTTTTGAGCATTCTTTCACTCCAGCCTAGCCCCTACCCCAGAACTAGGCGGACAGTGGCCCCCAGCAGGAATTAACCCCCTTAATCCCCTAGAAGTCCCACTACTAAACACGGCAATCC
TCCTCGCCTCAGGCGTCACTGTAACATGAACCCACCACAGCATCATAGAAGGTAACCGAAAACAAGCAACCCACGCACTCTCCCTAACTATCCTCCTCGGTTTTTATTTCACAGCACTACAGGCAAT
AGAGTACTACGATGCGCCATTTTCAATCGCCGATAGCGTGTATGGTTCAACCTTCTTCGTCGCTACAGGCTTCCACGGACTCCACGTAATCATCGGATCCTCCTTCCTATCTGTCTGCCTTCTACGCCT
AATTAATTTCCATTTCACATCTAACCACCACTTCGGATTCGAAGCAGCCGCCTGATACTGGCACTTCGTTGATGTCATCTGATTATTCCTCTACATAACAATCTACTGATGAGGATCCTGCTCTTCTAG
TATACTAATTACAATTGACTTCCAATCTATAGAATCTGGTGTAACCCCAGAGAAGAGCAATCAACATAATTACTTTCATACTAACCCTAACCCTCACCCTAAGCATCCTTCTAATCACATTAAACCTC
TGACTCGCCCAAACAAACCCAGACTCAGAAAAACTATCCCCATATGAATGTGGCTTTGATCCCCTAGGATCTGCCCGACTACCATTCTCAATCCGATTCTTCCTAGTAGCCATCCTATTCCTGCTATTC
GACCTAGAAATCGCACTCTTACTCCCTCTGCCATGAGCCATGCAACTCCAATCCCCCACCACCACTTTAACCTGGGCCTCCATTATCATCTCCCTCCTCACACTAGGATTAATCTATGAATGACTTCAA
GGGGGCCTAGAATGAGCCGAATAACCCCTACAGAGCGGTAGTCTAACCAAGACAGTTGATTTCGACTCAACAAATCATAGATCGACCCTATGCCTCTCTCTATGTCACTCCTACACCTAAGCTTCTA
CTCTTCCTTTACCCTAAGCTGCTTAGGGCTGGCCTTCCACCGAACCCACTTAATCTCTGCCCTACTATGCTTAGAAAGCATAATACTCTCCATATATATTGCCCTATCAATCTGACCCACCGAAACCCA
AACAGCATCCACCGCCCTAACCCCTATTCTCATACTGACATTCTCAGCCTGCGAGGCAGGCATCGGTCTAGCCATGCTAGTCGCCTCCACACGAACCCACGGATCTGACCACCTACACAACCTGAAC
CTCCTACAATGCTAAAAATCCTTCTTCCAACAATTATACTCCTACCCACAGCCCTCCTATCCCCCCAAAAATCCCTATGAACGAGCACCACTACTCACAGCCTCCTAATCGCCACTATCAGCCTTCACT
GACTACTCCCCACATACTACCCCCACAAAAACCTAACTCAATGGACAAGTATCGACCAAATCTCATCACCCTTGCTAGTCCTATCCTGCTGACTACTCCCTCTCATAATCCTAGCAAGCCAAAACCAC
CTGCAACACGAACCACCAATCCGCAAGCGAATCTTCATTACCACACTAATTACAGTACAACCCCTCCTCCTACTAGCATTCTCCGCCACCGAACTTATACTGTTCTATATCACATTTGAAGCCACCCT
AATCCCTACTTTAATCCTAATCACACGCTGAGGAAGCCAACCAGAGCGCCTAAGCGCGGGCATTTACCTACTATTCTACACCCTTATCAGCTCTCTACCACTGTTAGTCACAATCCTCTACCTTCACA
CACATATCGGCACCCTCCACCTCACAATGCTCAAACTATCCCACCCAACACTCACCACCTCCTGAACCGACCTCCTACTAAGCTTAGCACTGCTAATGGCATTCATAGTAAAAGCACCCCTCTATGGC
CTCCACCTATGACTACCCAAAGCCCACGTAGAAGCTCCAATCGCAGGATCAATGCTGCTCGCCGCCCTACTCCTAAAGCTAGGAGGCTATGGCATTATACGCCTCACCCTCCTAATCAACCCCCTCTC
CCCCCACCTACATTACTCCTTTCTCACCCTAGCCCTCTGAGGCGCACTAATAACCAGCTCAATCTGCCTGCGCCAAACCGACCTAAAATCTCTCATCGCTTACTCCTCCGTAAGCCACATAGGCCTAG
TCATCGCCGCAAGCATCCTCCAAACCCATTGATCATTCTCAGGAGCAATAATCCTAATAATCTCCCACGGACTGACCTCCTCAATACTATTCTGCCTAGCAAATACAACCTATGAACGTACCCACAGC
CGAACTCTCCTTCTAACACGAGGCCTCCAACCCCTCCTACCTCTTATAGCAACCTGATGACTTCTAGCCAACCTCACAAACATAGCCCTACCTCCAACCACAAACCTAATAGCAGAATTGACCATCAT
AACCGCATTATTCAACTGATCCACCCTCACTATCATCCTAACAGGCACCGCAACCTTACTAACCGCTTCATACACCCTATCCATATTACTAACAACCCAACGAGGTACCCTACCAACCCACATCACCT
CACTACAAAACTCAAGCACACGAGAACATCTCCTAATAGTCCTCCACATCACCCCTCTACTCCTCCTAATCCTTAAACCAGAAATAATCTCAGGAATACCCTTATGCAAGTATAGTTTCAACCCAAAC
ATTAGACTGTGACTCTAAAAATAGAAGTTAGACCCTTCTTACCTGCCGAGGGGAAGTTCAACTAGCAAGAACTGCTAATTCCTGCATCTGAGCCTAGAACCTCAGTCCCCTCAACTTTTAAAGGATA
ACAGCAATCCATTGGTCTTAGGAGCCACTCATCTTGGTGCAAATCCAAGTAAAAGTAATGGAAACAACATTACTCCTCAACACCTCCATACTTCTCACACTAACTATTATCCTCGTACCCATTCTCCT
CTCACTCCTCTCAACCACCCACTCAATCCCACCAACTACCATTACACTCACTATCAAAACAGCCTTTCTAACTAGTCTAGTACCCATAGCTATCTTCATGTACTCAGGGTCAGAAAGCATTATCTCCCA
TTGGGAATGAAAATTCATTACGAACTTTAAAATTCCCTTCAGCCTTAAAATTGACCAATACTCCATGATATTCTTCCCCATCGCACTATTTGTAACATGATCCATCCTCCAATTCGCACTATGATACAT
AGCATCCGAACCACACATCACAAAATTCTTCTTCTTCCTACTAATATTCCTAATTGCCATACTCACACTAACAATCGCCAACAACATATTCCTCCTGTTCATTGGCTGAGAAGGAGTCGGAATCATGT
CCTTCCTACTAATCGGATGATGACAAGGCCGGGCAGAAGCCAACACAGCCGCACTCCAAGCGGTCCTCTACAACCGAATTGGAGATATTGGCCTCATCCTAAGCATAGCATACCTAGCCTCAACAAC
AAATACCTGAGAAATCCAACAAGCACTCTCCCCTAACCAAGCTCCAACCCTCCCCCTACTGGGATTTATCCTAGCAGCTACAGGAAAATCTGCCCAATTTGGCCTCCATCCCTGACTGCCCGCCGCCA
TAGAAGGCCCAACCCCAGTCTCCGCCCTACTCCACTCCAGCACCATAGTAGTAGCCGGAATCTTCCTACTCATCCGCATCCACCCCCTACTCTCCACCAACCAAACCGCCCTCACCCTATGTCTCTGC
TTAGGAGCACTATCCACACTATTCGCTGCCATCTGTGCCCTAACACAGAATGACATTAAAAAAATCATCGCCTTCTCTACATCCAGCCAACTTGGACTAATAATAGTTACTATTGGATTAAACCTTCC
ACAACTAGCCTTTTTCCACATTTCAACACATGCCTTCTTCAAAGCCATACTGTTCCTCTGCTCAGGATCAATCATCCACGCCCTCAATGGAGAACAAGACATTCGAAAAATAGGAAGCCTCCAAAAA
ACACTTCCAACAACCACAACCTGTCTAACCATCGGAAACCTGGCCCTAATAGGAACCCCATTTCTAGCAGGATTTTACTCAAAAGATCTAATCATCGAAAGCCTCAATACCTCCTACTTAAATGCCTG
AGCCCTACTCCTAACACTCCTAGCAACATCATTTACAGCAACATATAGCCTACGCATAACCCTACTAGTCCAAACAAGCTTCCCCCGCATACCCACTATTACTCCCATAAATGAAAACACCCCAACCC
TCATTAACCCAATCACTCGACTCGCCCTGGGTAGCATTATGGCGGGTTTACTCATTACATCCTACATCCCCCCCACAAAAACACCCCCGATAACCATGCCCATACTCACAAAAACCACTGCAATCATC
ATCACAACCTTAGGCGTCATCCTAGCCCTAGAACTCTCAAACATAACCCACACCCTAACCCAACCAAAACAAACCCCACCCCTAAACTTCTCCTCTATACTGGGTTATTACAACTCTCTAACCCATCG
CCTCACCTCTCTAACCCTACTACACAGTGGACAAAAAATTGCCTCTCACCTAATCGACCTATCCTGATATAAAAAAATAGGCCCCGAAGGAATTGCTGACCTCCAGCTTACAGCAGCTAAAACCACA
ACCCCCCTCCACACCGGCCTAATCAAAGCCTACCTGGGAACCTTCGCCCTATCAACCTTCATCATCCTCCTATCAGCGCACTAACTTCCA
ARN del Aguila.
Se convierte la cadena de ADN a ARN.
AACUAAUGGCCCCCAAUCCCCGAAAGUCCCACCCCCUACUAAAAAUAGUCAAUAACUCCCUAAUCGACCUCCCCACCCCCUCAAACAUCUCUACUUGAUGAAACUUCGGCUCCCUCCUAGGAAU
CUGCCUAAUAACACAAAUCCUAACCGGCCUCCUAUUAGCCAUACACUACACCGCAGACACCACCCUAGCCUUCUCAUCCGUCGCCCACACAUGUCGGAACGUACAGUACGGCUGACUAAUCCGC
AACCUACAUGCCAACGGAGCAUCCUUCUUCUUCAUCUGCAUUUACCUUCACAUCGGCCGAGGACUCUACUACGGCUCAUACCUUUAUAAAGAGACCUGAAACACAGGAAUCAUUCUCCUACUU
ACCCUUAUAGCAACCGCCUUUGUAGGCUAUGUCCUCCCAUGAGGACAGAUAUCCUUCUGAGGAGCCACAGUCAUCACCAACCUAUUCUCAGCAAUCCCAUACAUCGGACAAACCCUCGUAGAG
UGGGCCUGAGGUGGAUUCUCUGUAGAUAACCCCACCCUCACUCGCUUCUUCGCCCUACAUUUUUUACUUCCAUUCCUUAUCGCAAGCCUUACCCUAAUCCACCUUACCUUCCUACACGAGUCC
GGAUCAAACAAUCCCCUAGGAAUUAUCUCAAACUGUGACAAAAUCCCAUUCCACCCCUACUUCUCCCUAAAAGACAUCCUAGGAUUCGUACUAAUACUACUCCCACUAACAACUCUAGCUCUA
UUCUCACCUAACCUGCUAGGCGACCCAGAAAACUUCACCCCAGCAAACCCCCUAGUUACACCCCCUCAUAUCAAACCAGAAUGAUACUUCCUAUUUGCAUACGCCAUCCUACGUUCAAUCCCA
AACAAGCUGGGAGGAGUGCUAGCUCUAGCUGCCUCAGUACUGAUCCUAUUCCUUAUCCCCUUCCUCCAUAAGUCCAAACAACGCACAAUAACCUUUCGACCCCUCUCCCAACUCCUAUUCUGG
ACCCUAAUCGCCAACCUCCUCAUCCUCACAUGGAUUGGCAGCCAACCAGUAGAACACCCGUUCAUUAUCAUCGGCCAACUCGCCUCCCUCACCUACUUCUCCACCCUCCUAAUCCUCUUCCCUC
UAAUUGGAGCCCUCGAAAAUAAAAUGCUCAACCACUAAAAAUACUCUAAUAGUUUAUAAAAAACAUUGGUCUUGUAAACCAAAGACUGAAGACUAUCCCCCUUCUUAGAGUUACCCGGCCCG
AAAGGGCCAUUAUUGCCAAAUUUUAUUUAAAACUCCCCUAGCAACGUAAUACAGGCGGCCCCCCCCCUCCCCCCCGUAUGUACUAUUGUACAUUCAACCAUUUACCGCAUAUCAUGCACCAUU
CAUAUGUAUACAUAUUAAUGAAUGUACUACGUUCAUAUACAUGUAAUACGGGCAUACAUCUCUUUGGGCCAUCUCUACUUUCAGGUACGGGUUUCACUUAAUGAACUCCUAGAUUGUCCUCG
AUCUCCCCCCGGGCUAGAUACAUACCAGAGGUGGUUCUCUGUGUAGAACUUGGUCUUCCCUACGGAUAUUCUUGGGGACAAACUCUGCAUGGUAGCAGGUCAUAACUUGCAAUCCUCUCUCG
UCGGACCGGUAGCUGUCGGACCAGGUUAUUUAUUGAUCGGGCUCCUCACGAGAAAUCAGCAACCUUACGGUGGUAGUAAGAUCCUACGUUACUAGCUUCAGGACCAUUCUUUCCCCCUACACC
CCUCGCACUACUUGCACUUUUGCGCCUCUGGUUCCUAUGUCAGGGCCACGACUUGGUUAGUCCUACGACCUUGCUCUUUACGAAUACAUCUGGUUGGCUAUUGAUCACCAUUCUGCCUCUUAA
UCGCGGCAUCCGGGUGGUUCUCUACUGUUGGUUCCCUUUUUUUUUUUGGGGUAACUUCACAGGUGGCCCUCAUAUAUGCACCGCGGCUCAUACAAUCUAAGACGUGGGCCCUCCUGGCCCUCG
GCCAGUCCUCGAUCUCAAGAGUUGAUUAAUGAGACGGUUUCAAGUAUCCGGGGAAUCAUUUUGACACUGUGCACUGGUCAGGAGCAUCUGGCUAUGGCGUGUCCACAGACCCUACUCAUGGU
GCUAUUUGGUGAAUGCUUGUGGGACAUGAUUUUAUAUUUUUUCUUUCCUCUGACUUUCUAAGUAUCACUAGGCGUUUCUAACUAAAACGCUAACCGUGUUUUUUCACAAAUUUUUUUCACUU
UUUUUCACAUUUUUUCACAUUUUUUUCAUUCGUUAAAGGCACUGAGGUUCCAUUAAUAAAUCAAACCAUUUCAUUCAUCAUUUUAUUCUUGUCAUUCAUCAAAUUUUUUCACAAAAUCACCC
CAAACAACCUCUAAAAAUCCAUUAAUAAUCAUUUCAUCAACAAACUUCAGAAAAAAAGGGCUCAAACCUCUAUCACCAACUCCCAAAGCUGGUAUUUUACAUUAAACUAUUCUCUGACAUCC
UUCCCCCCUAAACUGCCCGAAUCGCCCCACAAGAUAACCCACGUACAAGCUCCAACACAACAAACAACGUCAACAACAACCCUCACCCCGCUGCCAAAAACAUUCCUACCCCCCACGAAUAAAA
CAUAGCAACCCCACUAAAAUCCAACCGAGCCACAAAGACACCCCCCUCAUCAACAGUAACCACACCAAUCUUUCAACAUUCAACCCCGCUGACAACUACUCCUACAACAAGCGCCAAAACCAUU
CCCACUCCAUACCCCAAAACCCGCCAAUCCCCCCAUGCCUCCGGAAAAGGAUCCGCCGCUAAACACACCGAGUAGACAAAGACUACUAACAUUCCACCCAAGUACACCAUAAACAACACUAAAG
CUACAAACGGCACCCCCAAACUUACCAACCACCCACACCCUACAACAGACCCUAACACCAACCCAACAACCCCAUAAUAAGGUGACGGAUUAGAUGCAACUGCAAGCCCCCCUAGAACAAACCC
CGCCCCCAAAAGAAGAACAAAAUAAGCCAUUAUAAUUUCUGCUUGGCUUCUCUCCAAAAUCUACGACCUGAAAAAUCGUCGUUGUAAACUUCAACUACAGAAACCUAGCAAAUACUCCCACCC
AGCCUCCCCCUUAAACUCUAAAUAAUCUGCGCACUAAGUCCCACUAUUCACCCCGCCUUCUAUCCUAAGCAACACAUUCAACACCCGCACCACAUCCACAACAAACAUACCCCCAUUUCACCUC
CAAGCCCCCACUUUCAAGACCAGGCUUCACAACACAUACAAUCUAAACCAAGAACACUCCUACCUUCAAUCAACACCCAAUCCCAAAAUCCACUAACGAAACGGUUUCAAGUAUCCAAAAACA
CCAAAACACUAACCACGUUUUUCACGUAUUUUUUCACAUUUUUCACUUUCACAUUUUUUUGUUCACCAAAAGCACUGGAGUCUCAUUAAUUUUUUCAAAUCACAUAUCUCAUAUUUUAUUUG
UGUGUACACUAAACACACCAAAAUAUUAAAGAGACCCCCCUACUGAAUACACCAAACACAUAACACCACCACGCACCAACCCACAAACAGCAAGCAUACACAAGCUCAACCAACAAUAUAAAU
GAAUGAUUAGUUCUAAUAGAGCCGUGAACAAAUAACCAACAAUAUAAAUGAAUGAUUAGUUCUAAUAGAGCCGUGAACAAAUAACCAACAAUAUAAAUGAAUGAUUAGUUCUAAUAGAGCC
GUGAACUUAUAACAAAGCAUGGCACUGAAGAUGCCAAGAUGGCUACCGACCAUAGCCCGUGGACAAAAGACUUAGUCCUAACCUUACUGUUAACUCGUGCCAAAUAUAUACAUGCAAGUAUC
UGCGUCCCAGUGUAAAUGCCCUUGAUUCCUUACUAAGACGACAGGAGCAGGUAUCAGGCACACCCGCUCAACCGUAGCCCAAGACGCCUAGCUCAGCCACACCCCCACGGGUACUCAGCAGUA
AUUAACAUUAAGCAAUAAGUGUAAACUUGACUUAGUUAUGGCACUCUUAGGGUUGGUAAAUCUUGUGCCAGCCACCGCGGUCAUACAAGAGACCCAAGUUAACAGUUGUCCGGCGUAAAGAG
CGGGCACCUGCUAUCUAAGCAGCUGGGAUUAAACCACGGCUAAGCUGUCAUAAGCCCAAGGCGUGUUUAAAGCCAUCCCCAAGGCGAUCCCAACGCCCACGACCAACCAAACCCCGCGAAAGC
CAGGGCACAAACUGGGAUUAGAUACCCCACUAUGCCUGGCCCUAAAUCUUAAUACUUCCCCCACUAAAGUAUUCGCCCGAGUACUACGAGCACAAACGCUUAAAACUCUAAGGACUUGGCGGU
GCCCCAUACCCACCUAGAGGAGCCUGUUCUGUAAUCGAUAACCCACGCUACACCCCACCACUCCUAGCCCGGACAGCCUACAUACCGCCGUCGCCAGCUCACCUCCCUGAGAGACCAACAGUGA
GCCAAAUAGCCCCACCCGCUAAAAAGACAGGUCAAGGUAUAGCCCACGGAGUGGAAGAAAUGGGCUACAUUUUCUAAAGUAGAAAAUCACACGGAAGGGGGCGUGAAACAGCCCCUGGAAGG
CGGAUUUAGCAGUAAAGUGGGACAAUAAAGCCCUACUUAAGCCGGCCCUGAGGCACGUACAUACCGCCCGUCACCCUCCUCGCAAGCCAUAACCCAUCUAUAACUAAUAACCCAACUAGCUGA
AGAUGAGGUAAGUCGUAACAAGGUAAGUGUACCGGAAGGUGCACUUAGCAUACCAGGGCGUAGCUAUAAUGUAAAGCAUUCAGCUUACACCUGAAAGAUACCUACCACCGCCUAGGUCGCCC
UGAAGCCAAGCUCUAGCCCACACACCCCAACAAGCCAAAACCCAUUUUACCCACAAACUAAAGCAUUCUCUUAACUUAGUAUAGGCGAUAGAAAAGUUUUCCCCUGGCGCGAUAGAGAUCCGU
ACCGUAAGGGAAAGAUGAAAUAACAAUGAAACCCCAAGCAGCAUACAGCAAAGAUAAAUCCUUGUACCUCUUGCAUCAUGAUUUAGCAAGAAUAACCAAGCAAAACGAAUUUGAGCUUGCCU
CCCCGAAACCUGAGCGAGCUACCUAUAGGCAGCUGCCCCGAGCGAACCCGUCUCUGUUGCAAAAGAGUGGGAUGACCUAUUGGUAGUGGUGAAAAGCCAAUCGAGCUGGGUGAUAGCUGGUU
GCCUGUGAAACGAAUCUAAGUUCUUCCUUAGUUCCUCUCCACGGAUCCGUAGCCGAACCCUCACGUAGUGAACUAAGAGUAACUUAAAGGAGGUACAGCUCCUUUAAGAAAGAACACAAUCU
CUCAUAGCGGAUAACAUAACUUACCACUCCCCCGUAGGCCUUCGAGCAGCCAUCGACAAAGAAUGCGUCAAAGCUCCCUCCCCUAAAAAUGUGAAAACAACAUGACCCCCUCCCCACUAACAG
GCUAACCUAUCACAAUAGGAGAAUUAAUGCUAGAAUGAGUAACUAGGGCUUCCCCCUCUUAAGCGCAAGCUUACAUCACCCCAUUAUUAACAGCAUCUAAAUAAUAUUCUAAUCUCAACAAG
UCAGUAUAUUUAAAAUUACUCUGUUAACCCGACCCAGGAGCGCCCACUAGAAAGACUAAAAUCUGCAAAAGGAACUAGGCAACCCCAAGACCCGACUGUUUACCAAAAACAUAGCCCUCAGCA
AACCAAGUAUUGAAGGUGAUGCCUGCCCAGUGACCCUUAGUUCAACGGCCGCGGUAUCCUAACCGUGCGAAGGUAGCGCAAUCAAUUGUCCCAUAAAUCGGGACUUGUAUGAAUGGCUAAAC
GAGGCCUUAACUGUCUCUUGCAGAUAGUCCGUGAAAUUGAUCUUCCUGUGCAAAAGCAGGGAUGAGCACAUAAGACGAGAAGACCCUGUGGAACUUAAAAAUCAACAGCCACCACAUAUAAC
UACACACCUACUAGGCUCACAACCAAAAUUAAGUCCUGGUCUGCAUUUUUCGGUUGGGGCGACCUUGGAGAAAAGAAAAACCUCCAAAAAUAAGACCACACCUCUUAACCAAGAGCAACUUC
UCAACGUACCAACAGUAACCAGACCCAAUAACAAUUGAUCAAUGGACCAAGCUACCCCAGGGAUAACAGCGCAAUCCCUCCCAAGAGCUCCUAUCGACGGAGGGGCUUACGACCUCGAUGUUG
GAUCAGGACAUCCUAAUGGUGCAGUCGCUAUUAAGGGUUCGUUUGUUCAACGAUUAACAGUCCUACGUGAUCUGAGUUCAGACCGGAGCAAUCCAGGUCGGUUUCUAUCUAUGCAGCACUUU
CCCUAGUACGAAAGGACCGGGAAAGUAAGGCCAAUACCACAAGCAUGCCUUCUCCCUAAAUAAUGACCUCAACUAAACUAUAAAAGGAACCCCCACUUACCUCCCAAGCCCUAGAAAAGGGCC
GCUAGCGUGGCAGAGCCCGGUAAAUGCAGAAGGCUUAAGCCCUUUACCCAGAGGUUCAAGUCCUCUCUCUAGCCCUACCCACAAUGACCCGUCCCUCUAUCCUAACUCACCUUGCCAUAGCCC
UAUCCUACGCAAUCCCCAUCCUAAUCGCCGUAGCCUUCCUAACACUAGUAGAACGAAAAAUCCUAAGCUACAUACAAGCUCGGAAAGGUCCAAACAUUGUUGGGCCCUUCGGACUACUACAGC
CCGUAGCUGAUGGCGUGAAACUAUUUAUCAAGGAACCAAUCCGCCCCUCUACCUCCUCUCCCCUCCUCUUCACCAUAACGCCCAUGCUAGCCCUCCUCCUAGCAUUAACCAUUUGAAUUCCCCU
UCCCCUCCCCUUUCCCCUUGCUGACCUAAACCUAGGACUACUCUUCCUCCUAGCAAUAUCUAGCCUAGCAGUCUACUCAAUCCUGUGAUCUGGAUGAGCCUCAAAUUCAAAAUAUGCAUUAAU
UGGAGCCCUCCGGGCAGUAGCACAGACCAUCUCUUACGAAGUCACACUCGCCAUCAUUCUCCUAUCCGUAAUUCUUCUGAGCGGGAACUACACCCUGCACACGCUCACUACCACUCAAGAACC
UCUCUACCUCAUCUUCUCAUCCUGGCCCCUCACAAUAAUAUGAUAUAUCUCCACACUAGCCGAGACAAACCGAGCCCCCUUCGACCUCACAGAAGGAGAAUCCGAGUUAGUUUCAGGCUUUAA
CGUAGAAUAUGCCGCAGGACCAUUUGCCCUAUUCUUCCUUGCCGAAUACGCAAACAUUAUACUAAUAAACACACUAACCACAAUUCUAUUCCUAAACCCCAGCUCACUUAACCUGUCCCCCCA
ACUAUUUACAGUAGCCUUAGCAACGAAAAUUCUGCUCCUCUCCUCUGGAUUCCUAUGAAUUCGCGCCUCAUACCCACGCUUCCGCUACGACCAACUCAUGCACCUUCUCUGAAAAAAUUUCCU
ACCCUUGACACUAGCACUAUGCCUCUGGCACAUUAGCAUACCAACCUGCUACGCAGGAGUACCUCCUUGCUUAAGGAAAUGUGCCUGAACGCAAAGGGUCACUAUGAUAAAGUGAACAUAGA
GGUAUACCAACCCUCUCAUUUCCUAAGACCUUGAACCCUAGAAAAGCAGGAAUCGAACCUACACAGAAGGGAUCAAAACCCUCCAUACUUCCUUUAUAUUAUUUCCUAGCAGGGUCAGCUAA
UAAAGCUAUCGGGCCCAUACCCCGAAAAUGAUGGUUCAACCCCUUCCUCUGCUAAUGAACCCCCACACAAAAUUACUCUCCUUCCUAAGCCUAAUCCUAGGCACAACCAUUACAAUCUCAAGC
ACCCACUGAGUAAUGGCCUGAACCGGACUAGAACUCAACACCCUCGCUAUCAUCCCAUUCAUUUCAAAAUCCCACCAUCCCCGAGCCAUCGAAGCUACAAUCAAGUACUUCCUAGUACAAGCA
ACAGCCUCAACCCUCCUCCUAUUCUCAAGCAUAACAAACGCAUGAUCUACUGGCCAAUGAGAUAUCACACAACUAACUCACCCCACCUCCUCCCUAUUACUGACAGUAGCAAUUGCAAUAAAA
CUAGGACUAGUACCUUUCCACUUCUGAUUCCCAGAAGUACUACAAGGCUCAUCCCUAACUACUGCCCUACUUCUCUCCACAAUAAUAAAACUCCCCCCAACUGCUCUCCUCUUUCUAACCUCU
CACUCACUCAAUCCUACACUACUAACCGCCAUAGCCAUCGCCUCCGUAGCCCUAGGAGGAUGAAUGGGCCUAAACCAAACACAACUCCGAAAAAUUCUGGCCUUUUCAUCCAUCGCCCACCUA
GGAUGGCUAACCGCAGUCAUCAUCUACAACCCUGAACUCGCCCUACUAACUUUCUACUUAUAUAUCCUAAUAACCACUACUGUAUUCCUCACCCUCAACUCAACCAAAACCCUAAAGCUAACA
ACCCUAAUAACAUCAUGAACAAAAUCCCCUACACUAAACGCAACCCUCAUACUAGUUCUACUCUCCCUAGCAGGGCUUCCCCCACUAACAGGCUUCCUACCCAAAUGACUCAUCAUCCAAGAA
CUAACCAAACAAGAAAUAGCCUCAACAGCCACAAUCAUUGCUACCCUCUCCCUCCUAGGACUAUUCUUUUACCUCCGUCUCGCAUACCACUCAACAAUUACACUACCACCCAACUCUACAAACC
ACAUAAAACUAUGGCACCUUACCAAGCCGACAAGUACCACAAUCGCCGCCCUCGCCGCCCUAUCAGUAUUAACCUUACCGCUCUCCCCUCUAAUCCUGACUACCACCUAGAAACUUAGGAUAA
CUGAUAAACCGAAGGCCUUCAAAGCCUUAAAUAAGAGUUAAACCCUCUUAGUUUCUGCUAAGAUCCGCAGGACACUACCCUGCAACCCCUGAAUGCAACUCAGAUACUUUAAUUAAGCUAGG
ACCUUACCUAGAUAGAUGGGCCUCGAUCCCAUAAAACCCUAGUUAACAGCUAGGUGCCCUAACCAGUGAGCUUCUACCUACCAGACCCUGGCACGUCCUUAACGCACAUCAAUGAGUUUGCAA
CUCACUAUGAACUUCACUACAAGGUCGAUAAGAAAGGGAAUUAAACCCCUGUAAAAAGGACUACAGCCUAACGCUUAAACACUCAGCCAUCUUACCUGUGACACUUAUCAAUCGAUGACUAU
UCUCAACCAACCACAAAGACAUCGGCACUCUAUACCUAAUCUUCGGCGCAUGGGCUGGCAUAGUCGGCACCGCCCUUAGCCUUCUUAUCCGCGCAGAACUUGGCCAACCUGGCACCCUCUUAG
GCGAUGACCAAAUCUACAAUGUAAUCGUCACCGCUCAUGCUUUCGUAAUAAUCUUCUUCAUAGUCAUACCAAUCAUAAUUGGAGGCUUUGGAAACUGACUUGUCCCACUCAUAAUUGGCGCC
CCCGACAUAGCCUUCCCACGCAUAAACAACAUGAGCUUCUGAUUACUCCCCCCAUCCUUCCUCCUCCUACUAGCCUCUUCAACAGUAGAAGCAGGGGCUGGCACCGGGUGGACUGUCUACCCCC
CACUAGCCGGCAACAUAGCCCACGCCGGCGCUUCGGUAGACCUAGCUAUCUUUUCCCUCCAUCUAGCAGGUAUCUCAUCCAUCUUAGGGGCCAUUAACUUUAUCACAACAGCCAUUAACAUAA
AACCCCCAGCCCUCUCCCAAUACCAAACACCCCUAUUCGUAUGAUCCGUUCUUAUUACCGCUGUCCUACUAUUACUCUCACUCCCCGUCCUAGCUGCUGGCAUCACUAUAUUACUUACAGACCG
AAACCUCAACACAACAUUCUUCGACCCCGCUGGCGGCGGUGACCCAAUUCUGUACCAACACCUCUUCUGAUUCUUCGGACACCCCGAAGUCUACAUCCUAAUUCUCCCAGGCUUUGGGAUCAU
CUCCCACGUAGUAACAUAUUACGCAGGCAAAAAAGAGCCAUUUGGCUACAUAGGAAUAGUCUGAGCCAUACUCUCCAUCGGAUUCCUAGGCUUCAUCGUAUGAGCCCACCAUAUAUUCACAG
UAGGAAUAGACGUAGACACCCGAGCAUACUUCACAUCUGCCACUAUAAUCAUCGCUAUUCCGACCGGUAUUAAAGUAUUCAGCUGACUGGCAACACUACAUGGAGGGACUAUCAAAUGAGAC
CCGCCCAUACUAUGAGCCCUAGGCUUCAUCUUCCUCUUCACCAUCGGAGGCCUAACCGGGAUCGUCCUAGCGAACUCCUCACUAGACAUCGCCCUGCACGAUACAUACUACGUAGUUGCCCAC
UUCCACUAUGUCCUCUCAAUAGGAGCCGUCUUCGCCAUCCUAGCAGGAUUCACUCACUGAUUCCCCCUACUAACAGGAUUCACCCUACACCCCACAUGAGCCAAAGCACAUUUUGGGGUUAUA
UUCACAGGAGUAAACCUAACCUUCUUCCCACAGCACUUCUUAGGCCUUGCCGGAAUACCCCGACGGUACUCAGACUACCCAGAUGCCUACACCCUAUGAAACACCAUGUCCUCUAUCGGCUCA
CUAAUCUCAAUAACGGCCGUAAUUAUGCUAAUAUUCAUUAUCUGAGAAGCCUUCGCCUCAAAACGAAAAGUCCCACAACCAGAUUUAACUACAACCAACGUUGAAUGAAUCCACGGCUGCCC
ACCUCCAUACCACACCUUCGAAGAACCAGCCUUCGUCCAAGUACAAGAAAGGAAGGAAUCGAACCCUCGUACACUGGUUUCAAGCCAGCCGCAUCUAACCACCUAUGCUUCUUUCUUCCCAUG
GGAUGUUAGUAAAACAAUUACCUAAUCUUGUCAAGAUUAAAUCACAGGUGAAAAUCCUGUACACCCCACCAUGGCCAACCACUCACAAUUUGGAUUCCAAGACGCCUCGUCACCCAUCAUAG
AAGAACUCGUCGAAUUCCACGAUCACGCCCUAAUAGUUGCACUAGCCAUCUGCAGCCUAGUCCUAUACCUCCUAGCACUUAUACUAAUAGAAAAACUAUCCUCAAACACUGUAGACGCCCAAG
AAAUCGAACUAAUCUGAACAAUCCUACCAGCCAUCGUCCUCAUCAUACUUGCCCUCCCAUCCUUACAAAUCCUAUACAUAACAGAUGAAAUCAACGAACCAGAUCUCACACUAAAGGCCAUCG
GCCACCAAUGAUACUGAACCUACGAGUACACAGACUUUAAAGACCUAACAUUCGACUCCUACAUAAUUCCAACAACAGAUCUUCCACCAGGACACUUCCGACUACUCGAAGUUGACCAUCGCG
UAGUCAUCCCAAUAGAAUCUCCCAUCCGCAUCAUCGUCACAGCCAACGAUGUCCUCCAUGCCUGAGCAGUCCCCGCACUGGGUGUAAAAACUGAUGCAAUCCCAGGGCGACUAAACCAAACAU
CAUUCAUCACAACCCGGCCUGGGGUCUUCUACGGCCAAUGUUCAGAAAUCUGUGGAGCUAACCACAGCUACAUGCCAAUCGUAGUAGAAUCAACCCCCCUAACCCACUUCGAACACUGAUCAU
CACUCAUAUCCUCCUAAUCAUUAAGAAGCUAUGCAACAGCACUAGCCUUUUAAGCUAGAGAAAGAGGACCAUCCGUCCCUCCUUAAUGAUAUGCCACAACUUAACCCAGCCCCAUGACUCCUC
AUCAUACUAGCAUCAUGACUAACCCUCACACUAAUCGUUCAACCCAAACUCUUAUUCUUUACCUCCACUAACAUCCUACCCAACAAACCCAUUACAACUAUCAACCUCUCCCCCUGAAACUGA
CCAUGAUCCUAAACUUCUUCGACCAAUUCACAAGCCCCUGCCUCUUAGGCAUCCCACUUAUCCUAAUUUCAAUGCUAUUCCCCACCUUAUUACUUCCCUCACCAACCAACCGAUGAAUUACCA
ACCGCCUCUCCGCACUCCAACUAUGAUUCAUCCACCUAGUCACAAAACAACUAAUACUACCCCUAAAUAAAGGAGGACAUAAAUGGGCUCUAAUCUUAGUAUCACUAAUAACUCUCCUACUAA
CAAUCAACUUACUAGGAUUACUGCCAUACACAUUCACCCCAACCACCCAACUAUCAAUAAACAUAGCCCUUGCCUUCCCCCUCUGACUAGCUACCCUCCUUACAGGCCUACGGAACCAGCCCAC
AGCAUCCCUAGGUCACCUUCUACCCGAAGGCACUCCAACACCACUAGUUCCUGCCUUAAUCCUAAUCGAAACUAUCAGCCUACUCAUUCGCCCCCUAGCCCUAGGUGUCCGCCUAACAGCAAAC
UUAACAGCAGGCCACCUACUAAUCCAACUCAUCUCCACCGCUACUACUACUCUGCUCCCCAUCCUCCCAACAGUAUCUGCUCUAACCGCACUAAUCCUGCUACUACUGACUAUCCUAGAAAUU
GCAGUAGCCAUAAUCCAAGCCUACGUCUUCGUCCUACUCCUAAGCCUAUACCUGCAGGAAAACAUCUAAUGGCCCACCAAGCACAUUCCUACCACAUAGUAGACCCUAGCCCCUGACCUAUCU
UCGGCGCUGCAGCUGCCCUGCUCACUACAUCCGGACUCAUCAUAUGAUUCCAUCACAACUCCUCUCAACUCCUGUCCAUAGGCAUUCUCUCCAUACUUUUAGUCAUACUACAAUGAUGACGAG
ACAUUGUACGAGAAAGCACAUUCCAAGGCCACCACACCCCCACUGUCCAAAAAGGCCUGCGAUAUGGAAUAAUCCUAUUCAUCACAUCCGAAGCAUUCUUCUUCCUUGGCUUCUUUUGAGCAU
UCUUUCACUCCAGCCUAGCCCCUACCCCAGAACUAGGCGGACAGUGGCCCCCAGCAGGAAUUAACCCCCUUAAUCCCCUAGAAGUCCCACUACUAAACACGGCAAUCCUCCUCGCCUCAGGCGU
CACUGUAACAUGAACCCACCACAGCAUCAUAGAAGGUAACCGAAAACAAGCAACCCACGCACUCUCCCUAACUAUCCUCCUCGGUUUUUAUUUCACAGCACUACAGGCAAUAGAGUACUACGA
UGCGCCAUUUUCAAUCGCCGAUAGCGUGUAUGGUUCAACCUUCUUCGUCGCUACAGGCUUCCACGGACUCCACGUAAUCAUCGGAUCCUCCUUCCUAUCUGUCUGCCUUCUACGCCUAAUUAA
UUUCCAUUUCACAUCUAACCACCACUUCGGAUUCGAAGCAGCCGCCUGAUACUGGCACUUCGUUGAUGUCAUCUGAUUAUUCCUCUACAUAACAAUCUACUGAUGAGGAUCCUGCUCUUCUAG
UAUACUAAUUACAAUUGACUUCCAAUCUAUAGAAUCUGGUGUAACCCCAGAGAAGAGCAAUCAACAUAAUUACUUUCAUACUAACCCUAACCCUCACCCUAAGCAUCCUUCUAAUCACAUUA
AACCUCUGACUCGCCCAAACAAACCCAGACUCAGAAAAACUAUCCCCAUAUGAAUGUGGCUUUGAUCCCCUAGGAUCUGCCCGACUACCAUUCUCAAUCCGAUUCUUCCUAGUAGCCAUCCUA
UUCCUGCUAUUCGACCUAGAAAUCGCACUCUUACUCCCUCUGCCAUGAGCCAUGCAACUCCAAUCCCCCACCACCACUUUAACCUGGGCCUCCAUUAUCAUCUCCCUCCUCACACUAGGAUUAA
UCUAUGAAUGACUUCAAGGGGGCCUAGAAUGAGCCGAAUAACCCCUACAGAGCGGUAGUCUAACCAAGACAGUUGAUUUCGACUCAACAAAUCAUAGAUCGACCCUAUGCCUCUCUCUAUGU
CACUCCUACACCUAAGCUUCUACUCUUCCUUUACCCUAAGCUGCUUAGGGCUGGCCUUCCACCGAACCCACUUAAUCUCUGCCCUACUAUGCUUAGAAAGCAUAAUACUCUCCAUAUAUAUUG
CCCUAUCAAUCUGACCCACCGAAACCCAAACAGCAUCCACCGCCCUAACCCCUAUUCUCAUACUGACAUUCUCAGCCUGCGAGGCAGGCAUCGGUCUAGCCAUGCUAGUCGCCUCCACACGAAC
CCACGGAUCUGACCACCUACACAACCUGAACCUCCUACAAUGCUAAAAAUCCUUCUUCCAACAAUUAUACUCCUACCCACAGCCCUCCUAUCCCCCCAAAAAUCCCUAUGAACGAGCACCACUA
CUCACAGCCUCCUAAUCGCCACUAUCAGCCUUCACUGACUACUCCCCACAUACUACCCCCACAAAAACCUAACUCAAUGGACAAGUAUCGACCAAAUCUCAUCACCCUUGCUAGUCCUAUCCUG
CUGACUACUCCCUCUCAUAAUCCUAGCAAGCCAAAACCACCUGCAACACGAACCACCAAUCCGCAAGCGAAUCUUCAUUACCACACUAAUUACAGUACAACCCCUCCUCCUACUAGCAUUCUCC
GCCACCGAACUUAUACUGUUCUAUAUCACAUUUGAAGCCACCCUAAUCCCUACUUUAAUCCUAAUCACACGCUGAGGAAGCCAACCAGAGCGCCUAAGCGCGGGCAUUUACCUACUAUUCUAC
ACCCUUAUCAGCUCUCUACCACUGUUAGUCACAAUCCUCUACCUUCACACACAUAUCGGCACCCUCCACCUCACAAUGCUCAAACUAUCCCACCCAACACUCACCACCUCCUGAACCGACCUCC
UACUAAGCUUAGCACUGCUAAUGGCAUUCAUAGUAAAAGCACCCCUCUAUGGCCUCCACCUAUGACUACCCAAAGCCCACGUAGAAGCUCCAAUCGCAGGAUCAAUGCUGCUCGCCGCCCUAC
UCCUAAAGCUAGGAGGCUAUGGCAUUAUACGCCUCACCCUCCUAAUCAACCCCCUCUCCCCCCACCUACAUUACUCCUUUCUCACCCUAGCCCUCUGAGGCGCACUAAUAACCAGCUCAAUCUG
CCUGCGCCAAACCGACCUAAAAUCUCUCAUCGCUUACUCCUCCGUAAGCCACAUAGGCCUAGUCAUCGCCGCAAGCAUCCUCCAAACCCAUUGAUCAUUCUCAGGAGCAAUAAUCCUAAUAAU
CUCCCACGGACUGACCUCCUCAAUACUAUUCUGCCUAGCAAAUACAACCUAUGAACGUACCCACAGCCGAACUCUCCUUCUAACACGAGGCCUCCAACCCCUCCUACCUCUUAUAGCAACCUGA
UGACUUCUAGCCAACCUCACAAACAUAGCCCUACCUCCAACCACAAACCUAAUAGCAGAAUUGACCAUCAUAACCGCAUUAUUCAACUGAUCCACCCUCACUAUCAUCCUAACAGGCACCGCA
ACCUUACUAACCGCUUCAUACACCCUAUCCAUAUUACUAACAACCCAACGAGGUACCCUACCAACCCACAUCACCUCACUACAAAACUCAAGCACACGAGAACAUCUCCUAAUAGUCCUCCACA
UCACCCCUCUACUCCUCCUAAUCCUUAAACCAGAAAUAAUCUCAGGAAUACCCUUAUGCAAGUAUAGUUUCAACCCAAACAUUAGACUGUGACUCUAAAAAUAGAAGUUAGACCCUUCUUACC
UGCCGAGGGGAAGUUCAACUAGCAAGAACUGCUAAUUCCUGCAUCUGAGCCUAGAACCUCAGUCCCCUCAACUUUUAAAGGAUAACAGCAAUCCAUUGGUCUUAGGAGCCACUCAUCUUGGU
GCAAAUCCAAGUAAAAGUAAUGGAAACAACAUUACUCCUCAACACCUCCAUACUUCUCACACUAACUAUUAUCCUCGUACCCAUUCUCCUCUCACUCCUCUCAACCACCCACUCAAUCCCACCA
ACUACCAUUACACUCACUAUCAAAACAGCCUUUCUAACUAGUCUAGUACCCAUAGCUAUCUUCAUGUACUCAGGGUCAGAAAGCAUUAUCUCCCAUUGGGAAUGAAAAUUCAUUACGAACUU
UAAAAUUCCCUUCAGCCUUAAAAUUGACCAAUACUCCAUGAUAUUCUUCCCCAUCGCACUAUUUGUAACAUGAUCCAUCCUCCAAUUCGCACUAUGAUACAUAGCAUCCGAACCACACAUCAC
AAAAUUCUUCUUCUUCCUACUAAUAUUCCUAAUUGCCAUACUCACACUAACAAUCGCCAACAACAUAUUCCUCCUGUUCAUUGGCUGAGAAGGAGUCGGAAUCAUGUCCUUCCUACUAAUCG
GAUGAUGACAAGGCCGGGCAGAAGCCAACACAGCCGCACUCCAAGCGGUCCUCUACAACCGAAUUGGAGAUAUUGGCCUCAUCCUAAGCAUAGCAUACCUAGCCUCAACAACAAAUACCUGAG
AAAUCCAACAAGCACUCUCCCCUAACCAAGCUCCAACCCUCCCCCUACUGGGAUUUAUCCUAGCAGCUACAGGAAAAUCUGCCCAAUUUGGCCUCCAUCCCUGACUGCCCGCCGCCAUAGAAGG
CCCAACCCCAGUCUCCGCCCUACUCCACUCCAGCACCAUAGUAGUAGCCGGAAUCUUCCUACUCAUCCGCAUCCACCCCCUACUCUCCACCAACCAAACCGCCCUCACCCUAUGUCUCUGCUUA
GGAGCACUAUCCACACUAUUCGCUGCCAUCUGUGCCCUAACACAGAAUGACAUUAAAAAAAUCAUCGCCUUCUCUACAUCCAGCCAACUUGGACUAAUAAUAGUUACUAUUGGAUUAAACCU
UCCACAACUAGCCUUUUUCCACAUUUCAACACAUGCCUUCUUCAAAGCCAUACUGUUCCUCUGCUCAGGAUCAAUCAUCCACGCCCUCAAUGGAGAACAAGACAUUCGAAAAAUAGGAAGCCU
CCAAAAAACACUUCCAACAACCACAACCUGUCUAACCAUCGGAAACCUGGCCCUAAUAGGAACCCCAUUUCUAGCAGGAUUUUACUCAAAAGAUCUAAUCAUCGAAAGCCUCAAUACCUCCUA
CUUAAAUGCCUGAGCCCUACUCCUAACACUCCUAGCAACAUCAUUUACAGCAACAUAUAGCCUACGCAUAACCCUACUAGUCCAAACAAGCUUCCCCCGCAUACCCACUAUUACUCCCAUAAA
UGAAAACACCCCAACCCUCAUUAACCCAAUCACUCGACUCGCCCUGGGUAGCAUUAUGGCGGGUUUACUCAUUACAUCCUACAUCCCCCCCACAAAAACACCCCCGAUAACCAUGCCCAUACUC
ACAAAAACCACUGCAAUCAUCAUCACAACCUUAGGCGUCAUCCUAGCCCUAGAACUCUCAAACAUAACCCACACCCUAACCCAACCAAAACAAACCCCACCCCUAAACUUCUCCUCUAUACUGG
GUUAUUACAACUCUCUAACCCAUCGCCUCACCUCUCUAACCCUACUACACAGUGGACAAAAAAUUGCCUCUCACCUAAUCGACCUAUCCUGAUAUAAAAAAAUAGGCCCCGAAGGAAUUGCUG
ACCUCCAGCUUACAGCAGCUAAAACCACAACCCCCCUCCACACCGGCCUAAUCAAAGCCUACCUGGGAACCUUCGCCCUAUCAACCUUCAUCAUCCUCCUAUCAGCGCACUAACUUCCA
Aminoacidos del Aguila
N*WPPIPESPTPY*K*SITP*STSPPPQTSLLDETSAPS*ESA**HKS*PASY*PYTTPQTPP*PSHPSPTHVGTYSTAD*SATYMPTEHPSSSSAFTFTSAEDSTTAHTFIKRPETQESFSYLPL*QPPL*AMSSHEDRYP
SEEPQSSPTYSQQSHTSDKPS*SGPEVDSL*ITPPSLASSPYIFYFHSLSQALP*STLPSYTSPDQTIP*ELSQTVTKSHSTPTSP*KTS*DSY*YYSH*QL*LYSHLTC*ATQKTSPQQTP*LHPLISNQNDTSYLHTPSY
VQSQTSWEEC*L*LPQY*SYSLSPSSISPNNAQ*PFDPSPNSYSGP*SPTSSSSHGLAANQ*NTRSLSSANSPPSPTSPPS*SSSL*LEPSKIKCSTTKNTLIVYKKHWSCKPKTEDYPPS*SYPARKGHYCQILFKTPL
AT*YRRPPPSPPYVLLYIQPFTAYHAPFICIHINECTTFIYM*YGHTSLWAISTFRYGFHLMNS*IVLDLPPG*IHTRGGSLCRTWSSLRIFLGTNSAW*QVITCNPLSSDR*LSDQVIY*SGSSREISNLTVVVRSYV
TSFRTILSPYTPRTTCTFAPLVPMSGPRLG*SYDLALYEYIWLAIDHHSAS*SRHPGGSLLLVPFFFLG*LHRWPSYMHRGSYNLRRGPSWPSASPRSQELINETVSSIRGIILTLCTGQEHLAMACPQTLLMVLFG
ECLWDMILYFFFPLTF*VSLGVSN*NANRVFSQIFFTFFHIFSHFFHSLKALRFH**IKPFHSSFYSCHSSNFFTKSPQTTSKNPLIIISSTNFRKKGLKPLSPTPKAGILH*TIL*HPSPLNCPNRPTR*PTYKLQHNKQ
RQQQPSPRCQKHSYPPRIKHSNPTKIQPSHKDTPLINSNHTNLSTFNPADNYSYNKRQNHSHSIPQNPPIPPCLRKRIRR*THRVDKDY*HSTQVHHKQH*SYKRHPQTYQPPTPYNRP*HQPNNPIIR*RIRCNCK
PP*NKPRPQKKNKISHYNFCLASLQNLRPEKSSL*TSTTET*QILPPSLPLKL*IICALSPTIHPAFYPKQHIQHPHHIHNKHTPISPPSPHFQDQASQHIQSKPRTLLPSINTQSQNPLTKRFQVSKNTKTLTTFFTYFF
TFFTFTFFCSPKALESH*FFQITYLIFYLCVH*THQNIKETPLLNTPNT*HHHAPTHKQQAYTSSTNNINE*LVLIEP*TNNQQYK*MISSNRAVNK*PTI*MND*F**SRELITKHGTEDAKMATDHSPWTKDLVLT
LLLTRAKYIHASICVPV*MPLIPY*DDRSRYQAHPLNRSPRRLAQPHPHGYSAVINIKQ*V*T*LSYGTLRVGKSCASHRGHTRDPS*QLSGVKSGHLLSKQLGLNHG*AVISPRRV*SHPQGDPNAHDQPNPAK
ARAQTGIRYPTMPGPKS*YFPH*SIRPSTTSTNA*NSKDLAVPHTHLEEPVL*SITHATPHHS*PGQPTYRRRQLTSLRDQQ*AK*PHPLKRQVKV*PTEWKKWATFSKVENHTEGGVKQPLEGGFSSKVGQ*SP
T*AGPEARTYRPSPSSQAITHL*LITQLAEDEVSRNKVSVPEGALSIPGRSYNVKHSAYT*KIPTTA*VALKPSSSPHTPTSQNPFYPQTKAFS*LSIGDRKVFPWRDRDPYRKGKMK*Q*NPKQHTAKINPCTSCI
MI*QE*PSKTNLSLPPRNLSELPIGSCPERTRLCCKRVG*PIGSGEKPIELGDSWLPVKRI*VLP*FLSTDP*PNPHVVN*E*LKGGTAPLRKNTISHSG*HNLPLPRRPSSSHRQRMRQSSLP*KCENNMTPSPLTG*
PITIGELMLE*VTRASPS*AQAYITPLLTASK*YSNLNKSVYLKLLC*PDPGAPTRKTKICKRN*ATPRPDCLPKT*PSANQVLKVMPAQ*PLVQRPRYPNRAKVAQSIVP*IGTCMNG*TRP*LSLADSP*N*SSC
AKAGMST*DEKTLWNLKINSHHI*LHTY*AHNQN*VLVCIFRLGRPWRKEKPPKIRPHLLTKSNFSTYQQ*PDPITIDQWTKLPQG*QRNPSQELLSTEGLTTSMLDQDILMVQSLLRVRLFND*QSYVI*VQTG
AIQVGFYLCSTFPSTKGPGK*GQYHKHAFSLNNDLN*TIKGTPTYLPSPRKGPLAWQSPVNAEGLSPLPRGSSPLSSPTHNDPSLYPNSPCHSPILRNPHPNRRSLPNTSRTKNPKLHTSSERSKHCWALRTTTAR
S*WRETIYQGTNPPLYLLSPPLHHNAHASPPPSINHLNSPSPPLSPC*PKPRTTLPPSNI*PSSLLNPVIWMSLKFKICINWSPPGSSTDHLLRSHTRHHSPIRNSSERELHPAHAHYHSRTSLPHLLILAPHNNMIYL
HTSRDKPSPLRPHRRRIRVSFRL*RRICRRTICPILPCRIRKHYTNKHTNHNSIPKPQLT*PVPPTIYSSLSNENSAPLLWIPMNSRLIPTLPLRPTHAPSLKKFPTLDTSTMPLAH*HTNLLRRSTSLLKEMCLNAKG
HYDKVNIEVYQPSHFLRP*TLEKQESNLHRRDQNPPYFLYIIS*QGQLIKLSGPYPENDGSTPSSANEPPHKITLLPKPNPRHNHYNLKHPLSNGLNRTRTQHPRYHPIHFKIPPSPSHRSYNQVLPSTSNSLNPPPI
LKHNKRMIYWPMRYHTTNSPHLLPITDSSNCNKTRTSTFPLLIPRSTTRLIPNYCPTSLHNNKTPPNCSPLSNLSLTQSYTTNRHSHRLRSPRRMNGPKPNTTPKNSGLFIHRPPRMANRSHHLQP*TRPTNFLLI
YPNNHYCIPHPQLNQNPKANNPNNIMNKIPYTKRNPHTSSTLPSRASPTNRLPTQMTHHPRTNQTRNSLNSHNHCYPLPPRTILLPPSRIPLNNYTTTQLYKPHKTMAPYQADKYHNRRPRRPISINLTALPSNP
DYHLET*DN**TEGLQSLK*ELNPLSFC*DPQDTTLQPLNATQIL*LS*DLT*IDGPRSHKTLVNS*VP*PVSFYLPDPGTSLTHINEFATHYELHYKVDKKGN*TPVKRTTA*RLNTQPSYL*HLSIDDYSQPTTKT
SALYT*SSAHGLA*SAPPLAFLSAQNLANLAPS*AMTKSTM*SSPLMLS**SSS*SYQS*LEALETDLSHS*LAPPT*PSHA*TT*ASDYSPHPSSSY*PLQQ*KQGLAPGGLSTPH*PAT*PTPALR*T*LSFPSI*QVS
HPS*GPLTLSQQPLT*NPQPSPNTKHPYSYDPFLLPLSYYYSHSPS*LLASLYYLQTETSTQHSSTPLAAVTQFCTNTSSDSSDTPKSTS*FSQALGSSPT**HITQAKKSHLAT*E*SEPYSPSDS*ASSYEPTIYSQ*
E*T*TPEHTSHLPL*SSLFRPVLKYSADWQHYMEGLSNETRPYYEP*ASSSSSPSEA*PGSS*RTPH*TSPCTIHTT*LPTSTMSSQ*EPSSPS*QDSLTDSPY*QDSPYTPHEPKHILGLYSQE*T*PSSHSTS*ALPEY
PDGTQTTQMPTPYETPCPLSAH*SQ*RP*LC*YSLSEKPSPQNEKSHNQI*LQPTLNESTAAHLHTTPSKNQPSSKYKKGRNRTLVHWFQASRI*PPMLLSSHGMLVKQLPNLVKIKSQVKILYTPPWPTTHNLD
SKTPRHPS*KNSSNSTITP**LH*PSAA*SYTS*HLY**KNYPQTL*TPKKSN*SEQSYQPSSSSYLPSHPYKSYT*QMKSTNQISH*RPSATNDTEPTSTQTLKT*HSTPT*FQQQIFHQDTSDYSKLTIA*SSQ*NLPS
ASSSQPTMSSMPEQSPHWV*KLMQSQGD*TKHHSSQPGLGSSTANVQKSVELTTATCQS**NQPP*PTSNTDHHSYPPNH*EAMQQH*PFKLEKEDHPSLLNDMPQLNPAP*LLIILAS*LTLTLIVQPKLLFFTS
TNILPNKPITTINLSP*N*P*S*TSSTNSQAPAS*ASHLS*FQCYSPPYYFPHQPTDELPTASPHSNYDSST*SQNN*YYP*IKEDINGL*S*YH**LSY*QSTY*DYCHTHSPQPPNYQ*T*PLPSPSD*LPSLQAYGTSP
QHP*VTFYPKALQHH*FLP*S*SKLSAYSFAP*P*VSA*QQT*QQATY*SNSSPPLLLLCSPSSQQYLL*PH*SCYY*LS*KLQ*P*SKPTSSSYS*AYTCRKTSNGPPSTFLPHSRP*PLTYLRRCSCPAHYIRTHHMI
PSQLLSTPVHRHSLHTFSHTTMMTRHCTRKHIPRPPHPHCPKRPAIWNNPIHHIRSILLPWLLLSILSLQPSPYPRTRRTVAPSRN*PP*SPRSPTTKHGNPPRLRRHCNMNPPQHHRR*PKTSNPRTLPNYPPRFLF
HSTTGNRVLRCAIFNRR*RVWFNLLRRYRLPRTPRNHRILLPICLPSTPN*FPFHI*PPLRIRSSRLILALR*CHLIIPLHNNLLMRILLF*YTNYN*LPIYRIWCNPREEQST*LLSY*P*PSP*ASF*SH*TSDSPKQTQ
TQKNYPHMNVALIP*DLPDYHSQSDSS**PSYSCYST*KSHSYSLCHEPCNSNPPPPL*PGPPLSSPSSH*D*SMNDFKGA*NEPNNPYRAVV*PRQLISTQQIIDRPYASLYVTPTPKLLLFLYPKLLRAGLPPNPL
NLCPTMLRKHNTLHIYCPINLTHRNPNSIHRPNPYSHTDILSLRGRHRSSHASRLHTNPRI*PPTQPEPPTMLKILLPTIILLPTALLSPQKSL*TSTTTHSLLIATISLH*LLPTYYPHKNLTQWTSIDQISSPLLVLSC
*LLPLIILASQNHLQHEPPIRKRIFITTLITVQPLLLLAFSATELILFYITFEATLIPTLILITR*GSQPERLSAGIYLLFYTLISSLPLLVTILYLHTHIGTLHLTMLKLSHPTLTTS*TDLLLSLALLMAFIVKAPLYGLHL
*LPKAHVEAPIAGSMLLAALLLKLGGYGIIRLTLLINPLSPHLHYSFLTLAL*GALITSSICLRQTDLKSLIAYSSVSHIGLVIAASILQTH*SFSGAIILIISHGLTSSILFCLANTTYERTHSRTLLLTRGLQPLLPLIAT
**LLANLTNIALPPTTNLIAELTIITALFN*STLTIILTGTATLLTASYTLSILLTTQRGTLPTHITSLQNSSTREHLLIVLHITPLLLLILKPEIISGIPLCKYSFNPNIRL*L*K*KLDPSYLPRGSSTSKNC*FLHLSLEPQ
SPQLLKDNSNPLVLGATHLGANPSKSNGNNITPQHLHTSHTNYYPRTHSPLTPLNHPLNPTNYHYTHYQNSLSN*SSTHSYLHVLRVRKHYLPLGMKIHYEL*NSLQP*N*PILHDILPHRTICNMIHPPIRTMIH
SIRTTHHKILLLPTNIPNCHTHTNNRQQHIPPVHWLRRSRNHVLPTNRMMTRPGRSQHSRTPSGPLQPNWRYWPHPKHSIPSLNNKYLRNPTSTLP*PSSNPPPTGIYPSSYRKICPIWPPSLTARRHRRPNPSLRP
TPLQHHSSSRNLPTHPHPPPTLHQPNRPHPMSLLRSTIHTIRCHLCPNTE*H*KNHRLLYIQPTWTNNSYYWIKPSTTSLFPHFNTCLLQSHTVPLLRINHPRPQWRTRHSKNRKPPKNTSNNHNLSNHRKPGPN
RNPISSRILLKRSNHRKPQYLLLKCLSPTPNTPSNIIYSNI*PTHNPTSPNKLPPHTHYYSHK*KHPNPH*PNHSTRPG*HYGGFTHYILHPPHKNTPDNHAHTHKNHCNHHHNLRRHPSPRTLKHNPHPNPTKTN
PTPKLLLYTGLLQLSNPSPHLSNPTTQWTKNCLSPNRPILI*KNRPRRNC*PPAYSS*NHNPPPHRPNQSLPGNLRPINLHHPPISALTS
ANEXO 2. Secuencia de AND y ARN del Trepador pechiblanco
ADN Trepador Pechiblanco
GTCCCTGTAGCTTAAAAAAAGCATGACACTGAAGATGTTAAGATGGTAGCCTCATGCACCCAAGGACAAAAGACTTAGTCCTAACCTTACTGTTAGTTGTTGCTAGGTATATACATGCGAGTATCCG
CACTCCAGTGTAGATGCCCTGGACACCCTGACCTCAGGTAGATAGGAGCGGGTATCAGGCTCACCATCCTCGTAGCCCAAGACGCCTTGCAATTGCCACACCCCCACGGGTCCTCAGCAGTAGTTAA
TATTAAGCAATGAGTGTAAACTTGACTTAGCCATAGCAATATAAGGGCCGGTCAATCCTGTGCCAGCCACCGCGGTCATACAGGAGGCCCAAATTAACATTATAACGGCGTAAAGCGTGGTAGCAC
GTTATCCGAGTAACTAAGATTAAAAGGTTACTGAGCTGTCATAAGCCCAAGAAACCCATAAGACCACTTCTACAAAAGAAAATCTTAGAGCAACGACCAACTGAAATCCACGAAAGCCAGGGCCCA
AACTGGGATTAGATACCCCACTATGCCTGGCCCTAAATCTTGATGCTTTATACTACCCAAGCATCCGCCCGAGAACTACGAGCACTAACGCTTAAAACTCTAAGGACTTGGCGGTGCCCCAAACCCA
CCTAGAGGAGCCTGTTCTGTAATCGATGATCCACGATACTACCTGACCATCTCTCGCACAATCAGCCTACATACCGCCGTCTCCAGCTCACCTACACTGAAGGCCCAACAGTGAGCGCAATAGCCCA
CTCCGCTAGTAAGACAGGTCAAGGTATAGCCTATGGGATGGAAGTAATGGGCTACATTTTCTATAATAGAACATACGGCAAAGGGATTTGAAACTGTCCCTGGAAGGAGGATTTAGCAGTAAAGTG
GGACAATCGAGCCCTCTTTAAGCCGGCTCTGGGACACGTACATACCGCCCGTCACCCTCCTCAAAGGCGACCAACACCACTATAACTAATAAACTATCCAGCCAAAGATGAGGCAAGTCGTAACAA
GGTAAGTGTACCGGAAGGTGCACTTAGAACACCAAGACGTAGCTTAACTAAAGCATTCAGCTTACACCTGAAAGATGTCTGTCAACCACAGATCGTCTTGATGCCAAACTCTAGCCCAACAGACAT
GACCTAGAATAACAAAGTCACTGACTACACCTAAACAAAGCATTTACAAGTCCCAGTATAGGCGATAGAAAAGACACCATTGGAGCGATAGAGACTACGTACCGTAAGGGAAAGATGAAATAACA
GTGAACAACATAAGCTAAAAAAAGCAAAGATCAACCCTTGTACCTTTTGCATAATGGTCTAGCAAGAAAAACCAAGCAAAATGAATTTTAGTTTGCCACCCCGAAACCCAAGCGAGCTACTCACGA
GCAGCTATTATTGAGCGAACCCGTCTCTGTTGCAAAAGAGTGGGATGACTCGTTAGTAGAGGTGAAAAGCCAATCGAGCTGGGTGATAGCTGGTTGCCTGTGAAACGAATCTAAGTTCACTCTTAAT
TCTCCTCCAAGGAAACTCAACAAACCCTAATGAAGCGAATTAAGGGATATTTAAAGGGGGTACAGCTCCTTTAAAAAAGAATACAATCTCCACGAGCGGATAAATAACCTCACCAAACATACTTGT
GGGCCCTCAAGCAGCCATCAACGAAGAGTGCGTTAAAGCTCAGTACTACAAAAATATATAATCCTTATGAATCCCTCCTCACTAACAGGCTAACCTATACCCAAATAGGAGAATTAATGCTAGAATG
AGTAACCAGGGTCCTCCCTCTACGACGCAAGCTTACATCCGCACATTATTAACAAATCACTAGTATACGATAAATCAAACAAGCACAGTATTAAGTATATTGTTAACCCGACAGAGGAGCGTCCATT
AAGAAAGATTAAAACCTGTAAAAGGAACTAGGCAAACTATCAAGGCCCGACTGTTTACCAAAAACATAGCCTTCAGCAAACCATATACAAGTATTGAAGGTGATGCCTGCCCAGTGACCTAACGTT
TAACGGCCGCGGTATCCTAACCGTGCAAAGGTAGCGCAATCAATTGTCCCATAAATCGAGACTAGTATGAATGGCTAAACGAGGTCTTAACTGTCTCTTACAGGAAATCGGTGAAATTGATCTCCCT
GTGCAAAAGCAGGGATAAAACCATAAGACGAGAAGACCCTGTGGAACTTTAAAATCAGCGGCCACCCTAAACTACCTACACACCCACCGGGTTCACACCACACAAACTGCTGGCCCGCATTTTTCG
GTTGGGGCGACCTTGGAGAAAAACAGATCCTCCAAAAATTGGACCATACCTCTAGACTAAGAGCAACCCCTCAACGTGCTAATAGCAACCAGACCCAATATAATTGATCAATGGACCAAGCTACCC
CAGGGATAACAGCGCAATCTCCTCCGAGAGTCCATATCGACGAGGAGGTTTACGACCTCGATGTTGGATCAGGACATCCTAGTGGTGCAGCCGCTACTAAGGGTTCGTTTGTTCAACGATTAACAGT
CCTACGTGATCTGAGTTCAGACCGGAGTAATCCAGGTCGGTTTCTATCTATGACTAGCTCTTCCCAGTACGAAAGGATAGGAAAAGCAAGGCCAATACCACAAGCAAGCCTTCGCCCTAAGTAATGA
AACCAACTAAATTACGAAAGGCCCTCACACCAACCACGTCCTAGAAAAGGACAAGCTAGCGTGGCAGAGCTCGGCAAATGCAAAAGGCTTAAGTCCTTTAAATCAGAGGTTCAAATCCTCTCCCTA
GCTGCAACTCCAAATGACTAACTACCCACTACTAACCAGCCTAATTATAGCCCTCTCCTACGTCCTGCCCATTTTAATCGCAGTAGCCTTTCTCACGTTAGTCGAACGCAAAATCCTCAGCTACATGC
AAAACCGAAAAGGCCCAAATATCGTAGGACCATTCGGACTACTACAACCCCTAGCCGACGGGGTAAAACTATTCATCAAAGAGCCCATCCGCCCATCAACATCCTCTCCTATCCTATTTATTGCAAC
TCCAATACTAGCCCTTTTACTCGCAATCTCAATCTGAACTCCCCTTCCCCTTCCATTCCCACTAGCAGATCTAAACCTAGGCCTACTATTCCTGCTGGCCATGTCAAGCTTAGCAGTCTACTCAATTCT
ATGATCAGGATGAGCCTCCAACTCAAAATACGCCCTAATCGGAGCCCTACGAGCAGTAGCTCAAACCATTTCCTATGAAGTTACCCTAGCAATTATCCTATTATCAATTATCCTACTAACCGGGAGCT
ATACCCTCAACTCCATATCAATCGCTCAAGAACCACTATATCTCATCTTCTCCTGTTGACCCCTAGCCATAATATGATACGTATCTACATTAGCTGAAACAAACCGAGCCCCATTCGACCTTACAGAA
GGGGAATCTGAACTAGTATCAGGATTTAACGTAGAATATGCAGCAGGACCATTCGCCTTATTCTTCCTAGCAGAATATGCTAACATTATACTTATAAACACACTAACCGCTATCCTATTCTTCAACCC
AAGCATACTCAACCCACCCCAAGAATTATTCCCCATAATCCTTGCCACAAAAACCCTCCTACTCTCCGCAGGATTCCTATGAATTCGTGCCTCATACCCACGATTCCGATACGATCAGTTAATGCACC
TATTATGAAAAAACTTTCTCCCCCTAACACTGGCACTATGCCTATGACATACCAGCATGCCAATTTCCTATGCAGGCCTCCCTCCACATCTATAACCCCAAGGAAATGTGCCTGAACCCTAAAGGGTC
ACTATGATAAAGTGAACATAGAGGTATACCAACCCTCTCATTTCCTACCAAATTAGAAAAGTAGGAATTGAACCTACACCAGAGGGATCAAAACCCTCTATACTTCCCTTATATTATTTTCTACCACA
GCAGGGTCAGCTAAATAAGCTATCGGGCCCATACCCCGAAAATGATGGTTTAACCCCTTCCCCTGCTAATGAACCCCCAAGCAAAACTGGTCTTCACCACTAGCCTACTCCTGGGAACCACCATTAC
AATCTCAAGCAACCACTGAATCCTAGCTTGAACAGGCCTAGAAATCAACACTCTAGCCATTCTCCCCCTAATCTCAAAATCACACCACCCCCGCGCCGTCGAAGCCGCAACCAAGTACTTTCTAGTA
CAAGCAGCAGCCTCAGCCTTACTCCTATTCTCGAGCATGACCAATGCCTGGTACACAGGACAATGGGATATTACCCAACTAACACACCCCACCTCATGCTTAATTCTTACCTCAGCCATTGCAATCAA
ATTAGGCCTAGTACCATTCCACTTCTGATTCCCAGAAGTACTTCAAGGCTCCCCACTCACCACAGGCCTCCTACTATCAACAGCAATAAAATTCCCACCAATTACATTACTATTCATGACCTCTCAAT
CATTAAATTCAACCCTGCTAACTACTATAGCCATCCTATCCGCAGCCCTAGGAGGATGAATAGGCCTAAACCAAACACAAACCCGAAAGATCCTAGCCTTTTCCTCCATCTCTCACCTAGGCTGAAT
AGCCATTATCATCACATACAGCCCAAAACTCGCCCTATTAAACTTCTACCTATACACCCTCATAACCGCAGCCGTATTCCTCACCATAGACTCAATAAAAGTCCTTAAACTATCTACCCTAATAACCT
CATGAACAAAATCACCAGCACTAAGCACAACCCTACTGCTGACACTTCTATCTCTAGCAGGCCTCCCCCCTCTAACAGGATTCCTCCCAAAATGACTCATTATTCAAGAACTAACCAAACAAGAAAT
ACCTCTAATAGCAACAGCGATCTCATTACTGTCCCTACTAAGCCTATTTTTCTACCTACGTCTAGCATACTGCTCGACAATTACACTTCCCCCACACACTACAAACCACATAAAACGATGGCACACCC
ACAAACCCGTTAACACCCAAATCGCCATCCTAACTACCTTGTCCATCATACTCCTCCCCATCTCTCCCATCATCCTCACTATCATGTAAAGAAACTTAGGATCACCTAAACCGAAGGCCTTCAAAGCC
TTAAACAAGAGTTAAACCCTCTTAGTTTCTGCTAAGATTCGCAGGACATTACCCTGCATCCTCTGAATGCAACTCAGATGCTTTAATTAAACTAGAACCTTTCCAACATACTAGACAGGAGGGCTTCG
ATCCCACGATAATGCAGTTAACAGCTACATGCCTGAACCAACTGGCCTCTGCCTACAAGACTCCGGTACACAATTAATGTACATCAATGAGCTTGCAACTCACCATGAACTTCACTACAGAGCCGAT
AAGAAGAGGAATCAAACCTCTGTAAAAAGGACTACAGCCTAACGCTTATACACTCAGCCATCTTACCTGTGACATTCGTCAACCGATGATTATTCTCAACCAATCACAAAGACATCGGCACCCTATA
CCTAATTTTCGGTGCATGAGCCGGAATAGTGGGTACCGCCCTAAGCCTCCTCATTCGAGCAGAACTGGGCCAACCAGGCACTCTCCTGGGAGACGACCAAGTTTACAACGTAATCGTCACAGCCCAT
GCCTTCGTCATAATCTTTTTTATAGTTATACCAATTATAATCGGAGGATTCGGAAACTGACTAGTCCCCCTAATAATTGGAGCACCTGACATAGCATTCCCCCGAATAAACAATATAAGCTTCTGACT
CCTACCACCATCCTTCCTCCTACTCCTAGCCTCATCCACAATCGAAGCAGGAGTAGGTACAGGATGAACAGTGTACCCACCACTAGCCGGCAACCTGGCCCACGCTGGAGCCTCAGTCGACTTAGCT
ATCTTCTCCCTACACTTAGCGGGAATCTCCTCCATCTTAGGAGCAATTAACTTCATTACTACCGCAATCAACATAAAACCCCCTGCTCTCTCCCAATACCAAACCCCCCTATTCGTATGATCCGTGCTA
ATCACTGCAGTCTTACTGCTCCTCTCCCTACCAGTCCTAGCTGCAGGTATTACCATACTCCTAACAGACCGAAACTTAAACACCACCTTCTTCGACCCAGCAGGAGGAGGAGACCCAGTCCTATACCA
ACACCTATTCTGATTTTTCGGACACCCAGAAGTGTATATCCTGATCCTACCAGGATTTGGCATCATCTCCCACGTAGTAGCTTATTACGCAGGGAAAAAAGAACCGTTCGGCTACATAGGAATAGTCT
GAGCTATACTATCCATCGGTTTCCTAGGATTCATTGTCTGAGCACACCACATATTCACAGTAGGTATAGACGTAGACACCCGAGCATACTTTACATCAGCCACTATAATCATTGCAATCCCAACAGGT
ATCAAAGTGTTCAGCTGACTAGCAACACTGCACGGAGGCACAATTAAATGGGATCCCCCAATACTATGAGCCCTAGGATTCATCTTCCTATTCACTATTGGAGGGCTGACAGGAATCGTCTTAGCAA
ACTCCTCACTAGACATCGCCCTGCACGACACTTACTACGTAGTAGCTCACTTCCACTACGTCCTCTCCATAGGAGCAGTATTCGCCATCCTAGCAGGATTCACCCACTGATTCCCACTATTCACCGGA
TACACCCTACACTCCACATGAGCTAAAACCCAATTCGGAGTAATATTTGTAGGGGTAAATCTAACCTTCTTCCCTCAACATTTTCTAGGACTAGCCGGCATGCCTCGACGATATTCAGACTACCCAGA
CGCCTACACAATGTGAAATGCCATTTCCTCAGTAGGATCATTAATCTCAATAACAGCCGTAATCATACTAGTATTCATTATCTGAGAAGCCTTCGCATCTAAACGTGAAGTTCTTCACACTGAACTTA
CAAGCACTAACATCGAATGAATCCACGGCTGCCCACCTCCATTCCACACATTCGAAGAACCAGCCTTCGTCCAAGTCCAAGAAAGGAAGGAATCGAACCCCCATATGTTGGTTTCAAGCCAACCGC
ATATAAACCACTTATGCTTCTTTCTCATAAGAGACGTTAGTAAAACAATTACATAGCCTTGTCAAGACTAAATTACAGGTGAAAACCCAGTACGCCTCTACCCACTATAATGGCCAACCACTCACAA
TTAGGCTTCCAAGACGCATCATCACCCATCATAGAAGAACTAATCCAATTCCACGACCACGCTCTAATAGTAGCCTTATCTATTTGCAGCCTGGTCCTCTACCTTCTAGCCCACATACTTACAGAAAA
ACTGTCATCAAGCACAGTAAACGCACAAGAAATCGAACTTGTCTGAACAATCCTCCCAGCCATAGTCCTAATCATGCTCGCCCTACCGTCCCTACGAATCTTGTATATAATAGACGAGATCAATGAA
CCAGACCTAACACTCAAAGCCATCGGACATCAATGATACTGATCCTATGAATACACCGACATCAAAAATCTCACATTTGACTCTTACATAACACCCACAACAGACCTACCATTAGGACACTTCCGCC
TTCTAGAAGTAGACCATCGAGTTGTAGTTCCAACAAGCTCAACAGTCCGAGTCATCGTCACCGCTGACGATGTACTACACTCCTGAGCCGTCCCAAGCCTAGGTGTTAAAACTGACGCAATCCCAGG
ACGCCTTAATCAAACCTCATTCCTAACCCCACGACCTGGAGTCTACTACGGACAGTGTTCAGAAATCTGCGGCGCCAATCACAGCTTTATACCAATTGTAGTAGAAGCAACCCCATTAGCCAACTTT
GAAAACTGATCCTCTACACTATCCTCCTAATCATTAAGAAGCTATGGAACAGCACTAGCCTTTTAAGCTAGAGACAGAGGACTGCCCCCTCCTTAATGGTATGCCTCAGCTAAACCCAAATCCCTGA
TTTTTTATCATGATCACTTCATGACTAGTCCTAACACTAGTCATCCAACCCAAATTACTATCATTCTTAACCACAAACCCTCCATCCAACAAAACCCCAACAACTACAAACACCACCCCCTGAACCTG
ACCATGAACCTAAGCTTCTTTGACCAATTTTCAAGCCCATCCCTCCTAGGCATCCCGTTAGTTCTCATCGCAATAGTATTCCCAGCCCTACTAATCCCATCCCAGGACAACCGATGAGTAACCAACCG
ATTATCCACCCTCCAACTATGACTGGTTAATCTAATTACAAAACAACTAATGATACCATTAAACGAAAAAGGCCACAAATGAGCTCTAATCCTAACATCATTAATAATGTTCCTTCTACTGACAAATC
TGCTAGGTCTCCTCCCATACACATTCACCCCAACCACTCAACTATCCATAAACCTAGCACTAGCCTTCCCACTATGACTAGCCACTCTACTAACAGGACTACGAAACCAACCATCCCTCTCACTAGCC
CATCTACTTCCAGAAGGTACCCCAACACCACTAATCCCTGTCCTAGTTCTAATTGAAACAACCAGCCTCCTTATTCGTCCACTAGCCTTAGGAGTACGACTAACAGCCAACTTAACAGCAGGACACCT
TCTCATTCAACTAATCTCCACTGCCACAATAGTTCTATTCTCAACGATACCAACAGTCTCGCTACTAACCATCCCAATTCTCTTCTTACTAACAATCTTAGAAGTGGCAGTAGCTATAATCCAAGCCTA
CGTATTCGTACTCCTCCTAAGCCTCTACCTACAAGAAAACATCTAATTCACCCAAACAATGGCCCACCAAGCACACTCTTATCATATAGTAGACCCAAGCCCATGGCCCATTTTTGGAGCCGCCGCCG
CCCTCCTTACTACTTCAGGCCTGACCATATGATTCCATTATAACACCCCATACCTCCTAATCATAGGCCTAACATCCACAATCCTAGTCATATTCCAATGATGACGAGACATCGTACGAGAAAGCACG
TTCCAAGGACATCACACCCCCACAGTCCAAAAAGGCCTACGTTACGGCATGGTCCTGTTCATCACATCCGAAGCCTTCTTCTTCCTGGGCTTCTTCTGAGCCTTCTTCCATTCAAGCCTAGCCCCAACC
CCAGAACTAGGAGGACAATGACCTCCAGTAGGAATTAAACCCCTAAATCCAATAGAAGTCCCACTTCTAAATACAGCTATCCTCCTGGCTTCAGGCGTTACAGTTACATGGGCCCACCACAGCATCA
CAGAAGCCAACCGAAAACAAGCAATCCAAGCTCTCACCCTAACTGTCCTTCTAGGACTTTACTTCACTGCCCTCCAGGCCATGGAATATTACGAAGCCCCATTTTCCATCGCTGACGGAGTATACGG
CTCAACCTTCTTCGTAGCAACAGGATTCCACGGTCTTCACGTAATCATCGGCACTACATTCCTTCTAGTGTGCCTCCTACGCTTAATCAAATACCACTTCACATCAAACCATCATTTCGGCTTCGAAGC
AGCAGCATGATACTGACACTTCGTAGATGTCGTCTGATTGTTCCTCTACATCTCTATCTACTGATGAGGATCTTACTCTTCTAGTATATTTATTACAATCGACTTCCAATCCTTAAAATCTGGTTCAAC
CCCAGAGAAGAGTAATGAACATAGTCCTATTTATGATCGCCTTGTCTCTAACCCTAAGCATCGCCCTAACCACCCTAAACTTTTGGCTCGCCCAAATAAACCCAGACTCAGAAAAACTATCCCCATA
CGAATGCGGCTTCGACCCCCTAGGCTCTGCCCGCCTCCCATTCTCAATCCGTTTCTTCCTAGTAGCAATCCTATTCTTACTTTTCGACCTAGAAATCGCCTTATTACTCCCCCTCCCCTGAGCCGTGCAA
CTAGAATCACCTACCACCACACTAATCTGAGCCTCCACCATTATCGCCCTACTAACCCTAGGACTCATCTACGAATGAACCCAAGGAGGACTAGAATGAGCAGAGTAAAGAAAGTTAGTCTAACCA
AGACAGTTGATTTCGACTCAACAAATTATAGTTCTAACCCTATAACTTTCTTTATGACATACCTCCACCTAAGCTTCTTCTCCGCATTCACCCTAAGCAGCCTAGGACTAGCCTTTCACCGAACCCACC
TAATTTCAGCTCTCCTATGCCTAGAAAGTATAATATTATCTATATACATCGCCCTGGCCATATGACCAATCCAGACCCAGACAACATCACCAACACTACTACCCATCCTAATACTAACCTTTTCCGCC
TGCGAAGCCGGCACAGGACTAGCCCTACTAGTAGCTTCTACTCGAACCCACGGATCAGACCACCTTCACAACTTCAACCTACTACAATGCTAAAAATCATCGTACCAACCATTATACTCCTCCCCCTT
ACCTTCCTCTCACCTCCCAAACACTTATGAACTAACATTACCACGCACAGCCTACTAATCGCCACCATCAGCCTACACTGACTCACCCCAACCTACTACCCCAACAAAAACACCTCCTCGTGAACCGC
AATTGACCAAATCTCCTCCCCCCTACTAGTATTATCATGCTGACTCCTCCCCCTCATAATCATAGCAAGTCAAAACCACCTAGAACTGGAACCTCTTAATCGCAAACGAATCTTCGCCACAACTATTC
TCCTAGCCCAACCATTCATTCTAATTGCCTTCTCAGCCTCAGAACTAATACTTTTCTACATCGCATTTGAAGCCACCCTAATCCCAACTCTAATCCTCATCACACGATGAGGAAGCCAGCCAGAGCGA
CTAAACGCAGGCATTTATCTCCTATTCTACACACTAGCCAGCTCACTCCCCCTACTCATTATTATCCTAAACCTCCACAACCAAATCGGCACCCTCTACCTACCAGCACTAAAACTCTCCCATCCCACA
ATAACTACCTCATGATCAGGACTAATCTCAAGCCTCGCCCTCCTTCTAGCCTTTATGGTCAAAGCCCCACTTTACGGCCTTCATCTATGACTGCCTAAAGCCCACGTAGAAGCCCCCATCGCAGGCTC
CATACTACTAGCTGCCCTCCTACTAAAACTAGGAGGATATGGCATTATACGAGTCACTATCCTGGTAAACCCCGCACTAAACAACATACACTACCCCTTTATTACACTAGCCCTATGGGGAGCTGTCA
TAACCAGTGCCATTTGCCTACGACAAATCGACCTTAAATCACTAATCGCCTACTCATCCGTCAGCCACATAGGCCTAGTAGTAGCCGCAACTATAATCCAAACCCAATGAGCCTTTTCAGGGGCTAT
AATCCTAATAATTTCCCATGGCCTAACTTCTTCAATACTATTCTGCCTAGCTAACACCAACTATGAACGAACCCACAGCCGAATCCTACTTCTGACCCGAGGACTTCAGCCCCTACTTCCACTAATAG
CCATCTGATGACTCTTAGCCAACCTAACAAACATAGCCCTTCCTCCAACAACCAACCTGATAGCAGAACTAACAATTATAGTGGCTTTATTTAACTGATCTTCGATCACAATCATCCTAACAGGCACC
GCCATCCTACTAACTGCCTCATACACCCTATACATACTCACAATAACACAACGAGGCACACTCCCACCACACATCACATCAATCCAAAACTCCTCAACACGAGAACACCTCCTCATAGCCCTACACG
TAATTCCCATAATCCTCCTCATCCTAAAACCTGACCTTATTTCAGGCATCCCAATATGCAGGTATAGTTTTAACCCAAACATTAGACTGTGATCCTAAAGATAGAAGTTAGACTCTTCTTACCTGCCG
AGGGGAGGTTAAACCAGCAAGAACTGCTAACTCTTGCATCTGAGTATAAAACCTCAGCCCCCTTACTTTCAAAGGATAACAGTAATCCAATGGTCTTAGGAGCCACCCATCTTGGTGCAAATCCAAG
TGAAAGTAATGGATCTGCCACTAACCCTAAACACCCTAATACTACTAACCCTTGCCATTCTATTCACCCCAATTATCTTCCCAATACTATCCAACAAACTCAAAAACTCCCCTACCATCATCACAAGC
ACAGTTAAAACCTCATTCCTAATTAGCCTAGTCCCAATAGCAATCCACATCTACTCAAGTACAGAAAGCCTAATTTCCATCTGAGAATGAAAATACATCATAAACTTCAAAATCCCAATTAGCCTAA
AACTAGACTTCTACTCACTCACCTTCTTCCCAATCGCACTATTCGTATCCTGATCCATTCTACAATTCGCAACATGATACATAGCATCAGACCCACACATTACAAAATTCTTCACCTACCTCCTATTTT
TCCTTATCGCCATACTTATCCTAATCATCGCCAATAACCTATTCGTCCTGTTCATCGGCTGAGAAGGGGTAGGAATTATATCCTTCCTACTAATCAGCTGATGACACGGCCGAGCAGAGGCTAATACT
GCCGCCCTACAAGCCGTACTATACAACCGAGTAGGAGACGTAGGACTTATCCTCTGCATAGCATGACTGGCCTCCACAATAAACACCTGAGAGATCCAACAACTAACCTCCCCACACCAAACCCCC
ACACTACCCCTACTAGGCCTCATCCTAGCCGCAACAGGAAAATCTGCCCAATTCGGTCTACACCCATGACTACCAGCTGCAATAGAGGGCCCAACCCCCGTATCCGCCCTACTGCACTCAAGCACAA
TAGTAGTTGCCGGAATTTTCCTGCTAATCCGAACCCACCCTCTATTTAACAACAACCAAACCGCCCTCACCCTCTGCCTATGCCTCGGCGCCCTCTCCACATTATTCGCAGCTACATGCGCCCTTACTC
AAAATGACATCAAAAAAATCATTGCCTTCTCCACCTCCAGTCAACTAGGCCTAATGATAGTCACAATCGGACTAAACCAACCCCAATTAGCCTTTCTCCATATCTCCACCCACGCATTCTTCAAAGCA
ATACTATTCCTATGCTCCGGCTCAATTATCCACAACCTAAATGGGGAACAAGACATCCGAAAAATAGGAGGACTTCAAAAAATACTACCAACAACAACCTCATGCCTAACCATTGGCAACCTAGCCC
TAATAGGCACACCATTCCTTGCAGGATTCTACTCAAAAGACCAAATCATCGAAAGCTTGAGCACATCCTACCTAAACGCCTGAGCCCTACTCCTAACCCTACTAGCCACATCTTTCACTGCAATCTAT
ACAATACGCATAACAGTACTAGTACAATCAGGTTTCGTACGCACCCCTCCACTCACCCCTATAAACGAAAACAACCCAGCCGTAATCCTGCCCATCACCCGACTCGCACTAGGCAGCATCACAGCCG
GATTTTTCATCACCTCATTTATCACCCCAACAAAAACCCCCACATTAACCATACCATTATCCATTAAACTAACGGCAATCGTAGTTACAGCCCTAGGAATTGTACTAGCCCTAGAAATTACAAAAATG
ACCCAAACCCTAATCCTAAAAAAACAATCCACCCTATCAAATTTCTCAATCTCCCTAGGCTACTTCAACCCCCTAATACACCGTCTACATTCAACTACCATCCTGACCGGAGGCCAAAAACTTGCCTC
ACACCTAATCGACCTCTCATGATACAAACTAATAGGCCCAGAAGGACTAGCCAACCTACAGATAATAGCATCCAAAACCGCCACTACCTTACACTCAGGATCAACAAAAGCCTACCTAGGCTCCTTC
GCCCTATCCATCCTTATCATCCTCATATCTACATACAGAACCCTCCATAATGGCACTCAATCTTCGTAAAACCCACCCACTAATAAAAGTCGTCAATGATGCCCTAATCGACCTCCCAACCCCATCAA
ACATTTCAACTTGATGAAACTTCGGGTCACTCCTAGGCATCTGCCTAATTACCCAAATTGTAACCGGCCTCCTTCTAGCAACCCACTACACTGCAGACACCTCCTTAGCCTTCACTTCAGTCGCCCAC
ACCTGCCGAAACGTCCAATTCGGCTGACTCATCCGCAATCTCCATGCAAACGGAGCCTCATTCTTCTTCATCTGCATCTACCTACACATCGGCCGAGGAATCTATTACGGCTCATACCTAAACAAAGA
AACCTGAAATGTAGGAGTCATCCTACTCCTGACCCTTATAGCAACCGCCTTCGTAGGATATGTCCTGCCATGAGGACAAATATCATTCTGAGGGGCCACAGTAATTACCAACCTATTTTCTGCAATCC
CCTACATTGGCCAAACACTAGTAGAATGAGCTTGAGGAGGGTTCTCAGTAGACAACCCCACACTAACACGATTCTTCGCCCTTCACTTCCTACTCCCATTCCTTATTGCCGGACTCACACTTGTTCAC
CTAACCTTCTTACACGAAACGGGATCGAATAACCCCCTAGGAATCCCCTCAGACTGCGACAAAATCCCATTCCACCCATATTACACCACAAAAGACATTCTAGGCTTTGCCATCATACTAATCCTACT
TACAGCCATAGCACTATTCTCCCCAAACATACTAGGAGACCCAGAAAACTTCACCCCAGCCAACCCTCTAGTTACACCTCCACACATCAAACCTGAATGATACTTCCTATTCGCATACGCCATCCTAC
GATCAATCCCAAACAAACTAGGAGGTGTACTGGCCCTTGCCGCCTCCGTCCTAGTCCTATTCCTCTTACCCCTACTCCACACATCCAAACTACGCTCTATAACCTTCCGACCACTATCACAAATCCTAT
TCTGAACCCTCGTAGCTGACCTCCTCATTCTTACCTGAGTAGGCAGCCAACCAGTCGAACATCCCTTCATCATCATCGGACAGCTAGCCTCCCTAGCCTACTTCACAATTATTCTAGTCCTACTCCCAC
TCGCCTCCATCCTAGAGAACAAACTCCTAAAACTTTAACAGACTCTAATAGTTTATTAAAACATTGGTCTTGTAAGCCAAAGATTGAAGATTACACCCCTTCTTAGAGTTTCGCGTCTCAGAAAGAAA
GGAATCAAACCCTTATCACCAACTCCCAAAGCTGGAATTTTAATTAAACTACTTTCTGGTCACTACCCTAAACAGCCCGAATCGCCCCCCGCGACAACCCTCGTACTAACTCAAGTACTACAAACAA
AGTTAGCAACAACCCCCACCCCCCAATTAAAAACAACCCTACTCCGTCTGAATAAAAACCCGCCGCTCCACCAAAGTCCGTACGAACCATAGAAAGCCCCCCACCATTCACCGTACCACTATCCACA
ACCGACCCAAGACCACCCCACACAACAACCCCTACAACAACAACTAACCCCATCCCCAACCCATAACCAACAACCCCTCAATCCCCCCATGTCTCAGGGTACGGATCTGCAGCCAAAGACACTGAA
TACACAAACACCACCAACATACCACCTAAATAAACCATAACCAGCACCAAAGACACAAAAGAAACCCCCAAACTCACCAGTCACCCACACCCAGCAACAGACGCCAAGACTAATCCTACAACCCC
ATAATAAGGAGAAGGATTAGACGCCACCCCCAACCCCCCTAAAACGAGACACAGCCCTAAAAATACTACAAATTCTATCATAATTCCAGCCTGGCCTCTCTCCAGGATCAACGACCTGAAAAGTCG
TCGTTATTAGAAATTTAACTACAGGAACCCCCCCCCCCTTCCCCCCCCAACATGTTTCCTCATGTTTTCTCATGTTTTTTCTGTTATGTGGTTCTGCATCGCTCTCTTTAGCACATCAGACAACTACTAT
AATGTAGGATACTCCACGCCATACGTATTGCCTTGCCTCCAAAACCTCAAACATTATCTCCCATGAGATAATTTGCGAGCTATTACAGTTCTAGGGACTTCTTTGTTTCAGGTACCATTAACCCAAGT
GATCCTACCTCCAGCCGGAGCCGCAAGCGTTACTTAAGTTCGACTATATCTCCCTGCGCCTAAATTCCTTTCCTCAGGATACGACTAATATCCTAGTACACCTTTGCATTCACCTAGTCACGCACTTCG
CCCACCTCCTAGGATATATCCCTCTCCAACAGCCTTCAGGAACTCCCAAGCCAGAGAACCTGGTTATCTATTAATCGTGTTTCTCACGAGAACCGAGCTACTCGACGTCAGTTATACCTTCGGTTATT
GGTGTCAGGGGCATACATCTAATAAACTTGATCTCCAACGTGCCACCGGTTGTAATTTCAGGAACCCTACTCGCCTAATTTCTAATCAATTGCTCTTCACAGATACATATGCTTGGGGATGGACGCTC
CTCATAAATATCCGTAATCGCGGCTAGCCATAGGCCGTTTTAGCTCTTCTTTTCTTTCTGGGGTCTCTTCAATAAGCCCTTCCAGTGCGTAGCAGGAGATATCTTCCTCTTGACATGTCCATCACATGA
CCGGCGAACATACGTCTGCCCGAAACCACTTGGAATGTCATGGTTTGTGGAATAAGTAGACCAACTTTGACACTGATGCACTTTGACCGCATTCATGGGATCCGCGCCATTTACCTCTTACAAGTAGC
AGATAGTGTAATGGTTGGCAGGCATACTAATTTATTTGTCTTCTTCTAGGATTTGTCACCTAAACCCCGTTTTTTTCATTTTTTTTTCATTTTTTTTCTTTTTTGTTTGTCATTTTTCGTTCGCTTTAAACA
AACCAATAGCTATATAACCCTACATTTTCACAAATTTTTTGTCATCAATTAGTTTAACAACAAACTTTCCTCCAACATTCCCCCAAACACAAACTAACCATCCACCATCACTTTAACAACATTTTAACA
AACAAAACCACTCAAACAAACTGTACAAATCCAGCAACATTCACCCAACCCAAAAACCAAACAAAAATATAAAACAGTAACACAAAACAGCCAACAACTTCCCAGCACTAAT
ARN de trepador pechiblanco
Se convierte la cadena de ADN a ARN.
GUCCCUGUAGCUUAAAAAAAGCAUGACACUGAAGAUGUUAAGAUGGUAGCCUCAUGCACCCAAGGACAAAAGACUUAGUCCUAACCUUACUGUUAGUUGUUGCUAGGUAUAUACAUGCGAGU
AUCCGCACUCCAGUGUAGAUGCCCUGGACACCCUGACCUCAGGUAGAUAGGAGCGGGUAUCAGGCUCACCAUCCUCGUAGCCCAAGACGCCUUGCAAUUGCCACACCCCCACGGGUCCUCAGC
AGUAGUUAAUAUUAAGCAAUGAGUGUAAACUUGACUUAGCCAUAGCAAUAUAAGGGCCGGUCAAUCCUGUGCCAGCCACCGCGGUCAUACAGGAGGCCCAAAUUAACAUUAUAACGGCGUAA
AGCGUGGUAGCACGUUAUCCGAGUAACUAAGAUUAAAAGGUUACUGAGCUGUCAUAAGCCCAAGAAACCCAUAAGACCACUUCUACAAAAGAAAAUCUUAGAGCAACGACCAACUGAAAUCC
ACGAAAGCCAGGGCCCAAACUGGGAUUAGAUACCCCACUAUGCCUGGCCCUAAAUCUUGAUGCUUUAUACUACCCAAGCAUCCGCCCGAGAACUACGAGCACUAACGCUUAAAACUCUAAGGA
CUUGGCGGUGCCCCAAACCCACCUAGAGGAGCCUGUUCUGUAAUCGAUGAUCCACGAUACUACCUGACCAUCUCUCGCACAAUCAGCCUACAUACCGCCGUCUCCAGCUCACCUACACUGAAG
GCCCAACAGUGAGCGCAAUAGCCCACUCCGCUAGUAAGACAGGUCAAGGUAUAGCCUAUGGGAUGGAAGUAAUGGGCUACAUUUUCUAUAAUAGAACAUACGGCAAAGGGAUUUGAAACUGU
CCCUGGAAGGAGGAUUUAGCAGUAAAGUGGGACAAUCGAGCCCUCUUUAAGCCGGCUCUGGGACACGUACAUACCGCCCGUCACCCUCCUCAAAGGCGACCAACACCACUAUAACUAAUAAAC
UAUCCAGCCAAAGAUGAGGCAAGUCGUAACAAGGUAAGUGUACCGGAAGGUGCACUUAGAACACCAAGACGUAGCUUAACUAAAGCAUUCAGCUUACACCUGAAAGAUGUCUGUCAACCACA
GAUCGUCUUGAUGCCAAACUCUAGCCCAACAGACAUGACCUAGAAUAACAAAGUCACUGACUACACCUAAACAAAGCAUUUACAAGUCCCAGUAUAGGCGAUAGAAAAGACACCAUUGGAGC
GAUAGAGACUACGUACCGUAAGGGAAAGAUGAAAUAACAGUGAACAACAUAAGCUAAAAAAAGCAAAGAUCAACCCUUGUACCUUUUGCAUAAUGGUCUAGCAAGAAAAACCAAGCAAAAU
GAAUUUUAGUUUGCCACCCCGAAACCCAAGCGAGCUACUCACGAGCAGCUAUUAUUGAGCGAACCCGUCUCUGUUGCAAAAGAGUGGGAUGACUCGUUAGUAGAGGUGAAAAGCCAAUCGAG
CUGGGUGAUAGCUGGUUGCCUGUGAAACGAAUCUAAGUUCACUCUUAAUUCUCCUCCAAGGAAACUCAACAAACCCUAAUGAAGCGAAUUAAGGGAUAUUUAAAGGGGGUACAGCUCCUUUA
AAAAAGAAUACAAUCUCCACGAGCGGAUAAAUAACCUCACCAAACAUACUUGUGGGCCCUCAAGCAGCCAUCAACGAAGAGUGCGUUAAAGCUCAGUACUACAAAAAUAUAUAAUCCUUAUG
AAUCCCUCCUCACUAACAGGCUAACCUAUACCCAAAUAGGAGAAUUAAUGCUAGAAUGAGUAACCAGGGUCCUCCCUCUACGACGCAAGCUUACAUCCGCACAUUAUUAACAAAUCACUAGUA
UACGAUAAAUCAAACAAGCACAGUAUUAAGUAUAUUGUUAACCCGACAGAGGAGCGUCCAUUAAGAAAGAUUAAAACCUGUAAAAGGAACUAGGCAAACUAUCAAGGCCCGACUGUUUACCA
AAAACAUAGCCUUCAGCAAACCAUAUACAAGUAUUGAAGGUGAUGCCUGCCCAGUGACCUAACGUUUAACGGCCGCGGUAUCCUAACCGUGCAAAGGUAGCGCAAUCAAUUGUCCCAUAAAU
CGAGACUAGUAUGAAUGGCUAAACGAGGUCUUAACUGUCUCUUACAGGAAAUCGGUGAAAUUGAUCUCCCUGUGCAAAAGCAGGGAUAAAACCAUAAGACGAGAAGACCCUGUGGAACUUUA
AAAUCAGCGGCCACCCUAAACUACCUACACACCCACCGGGUUCACACCACACAAACUGCUGGCCCGCAUUUUUCGGUUGGGGCGACCUUGGAGAAAAACAGAUCCUCCAAAAAUUGGACCAUA
CCUCUAGACUAAGAGCAACCCCUCAACGUGCUAAUAGCAACCAGACCCAAUAUAAUUGAUCAAUGGACCAAGCUACCCCAGGGAUAACAGCGCAAUCUCCUCCGAGAGUCCAUAUCGACGAGG
AGGUUUACGACCUCGAUGUUGGAUCAGGACAUCCUAGUGGUGCAGCCGCUACUAAGGGUUCGUUUGUUCAACGAUUAACAGUCCUACGUGAUCUGAGUUCAGACCGGAGUAAUCCAGGUCGG
UUUCUAUCUAUGACUAGCUCUUCCCAGUACGAAAGGAUAGGAAAAGCAAGGCCAAUACCACAAGCAAGCCUUCGCCCUAAGUAAUGAAACCAACUAAAUUACGAAAGGCCCUCACACCAACCA
CGUCCUAGAAAAGGACAAGCUAGCGUGGCAGAGCUCGGCAAAUGCAAAAGGCUUAAGUCCUUUAAAUCAGAGGUUCAAAUCCUCUCCCUAGCUGCAACUCCAAAUGACUAACUACCCACUAC
UAACCAGCCUAAUUAUAGCCCUCUCCUACGUCCUGCCCAUUUUAAUCGCAGUAGCCUUUCUCACGUUAGUCGAACGCAAAAUCCUCAGCUACAUGCAAAACCGAAAAGGCCCAAAUAUCGUAG
GACCAUUCGGACUACUACAACCCCUAGCCGACGGGGUAAAACUAUUCAUCAAAGAGCCCAUCCGCCCAUCAACAUCCUCUCCUAUCCUAUUUAUUGCAACUCCAAUACUAGCCCUUUUACUCG
CAAUCUCAAUCUGAACUCCCCUUCCCCUUCCAUUCCCACUAGCAGAUCUAAACCUAGGCCUACUAUUCCUGCUGGCCAUGUCAAGCUUAGCAGUCUACUCAAUUCUAUGAUCAGGAUGAGCCU
CCAACUCAAAAUACGCCCUAAUCGGAGCCCUACGAGCAGUAGCUCAAACCAUUUCCUAUGAAGUUACCCUAGCAAUUAUCCUAUUAUCAAUUAUCCUACUAACCGGGAGCUAUACCCUCAACU
CCAUAUCAAUCGCUCAAGAACCACUAUAUCUCAUCUUCUCCUGUUGACCCCUAGCCAUAAUAUGAUACGUAUCUACAUUAGCUGAAACAAACCGAGCCCCAUUCGACCUUACAGAAGGGGAAU
CUGAACUAGUAUCAGGAUUUAACGUAGAAUAUGCAGCAGGACCAUUCGCCUUAUUCUUCCUAGCAGAAUAUGCUAACAUUAUACUUAUAAACACACUAACCGCUAUCCUAUUCUUCAACCCA
AGCAUACUCAACCCACCCCAAGAAUUAUUCCCCAUAAUCCUUGCCACAAAAACCCUCCUACUCUCCGCAGGAUUCCUAUGAAUUCGUGCCUCAUACCCACGAUUCCGAUACGAUCAGUUAAUG
CACCUAUUAUGAAAAAACUUUCUCCCCCUAACACUGGCACUAUGCCUAUGACAUACCAGCAUGCCAAUUUCCUAUGCAGGCCUCCCUCCACAUCUAUAACCCCAAGGAAAUGUGCCUGAACCC
UAAAGGGUCACUAUGAUAAAGUGAACAUAGAGGUAUACCAACCCUCUCAUUUCCUACCAAAUUAGAAAAGUAGGAAUUGAACCUACACCAGAGGGAUCAAAACCCUCUAUACUUCCCUUAUA
UUAUUUUCUACCACAGCAGGGUCAGCUAAAUAAGCUAUCGGGCCCAUACCCCGAAAAUGAUGGUUUAACCCCUUCCCCUGCUAAUGAACCCCCAAGCAAAACUGGUCUUCACCACUAGCCUAC
UCCUGGGAACCACCAUUACAAUCUCAAGCAACCACUGAAUCCUAGCUUGAACAGGCCUAGAAAUCAACACUCUAGCCAUUCUCCCCCUAAUCUCAAAAUCACACCACCCCCGCGCCGUCGAAG
CCGCAACCAAGUACUUUCUAGUACAAGCAGCAGCCUCAGCCUUACUCCUAUUCUCGAGCAUGACCAAUGCCUGGUACACAGGACAAUGGGAUAUUACCCAACUAACACACCCCACCUCAUGCU
UAAUUCUUACCUCAGCCAUUGCAAUCAAAUUAGGCCUAGUACCAUUCCACUUCUGAUUCCCAGAAGUACUUCAAGGCUCCCCACUCACCACAGGCCUCCUACUAUCAACAGCAAUAAAAUUCC
CACCAAUUACAUUACUAUUCAUGACCUCUCAAUCAUUAAAUUCAACCCUGCUAACUACUAUAGCCAUCCUAUCCGCAGCCCUAGGAGGAUGAAUAGGCCUAAACCAAACACAAACCCGAAAGA
UCCUAGCCUUUUCCUCCAUCUCUCACCUAGGCUGAAUAGCCAUUAUCAUCACAUACAGCCCAAAACUCGCCCUAUUAAACUUCUACCUAUACACCCUCAUAACCGCAGCCGUAUUCCUCACCA
UAGACUCAAUAAAAGUCCUUAAACUAUCUACCCUAAUAACCUCAUGAACAAAAUCACCAGCACUAAGCACAACCCUACUGCUGACACUUCUAUCUCUAGCAGGCCUCCCCCCUCUAACAGGAU
UCCUCCCAAAAUGACUCAUUAUUCAAGAACUAACCAAACAAGAAAUACCUCUAAUAGCAACAGCGAUCUCAUUACUGUCCCUACUAAGCCUAUUUUUCUACCUACGUCUAGCAUACUGCUCGA
CAAUUACACUUCCCCCACACACUACAAACCACAUAAAACGAUGGCACACCCACAAACCCGUUAACACCCAAAUCGCCAUCCUAACUACCUUGUCCAUCAUACUCCUCCCCAUCUCUCCCAUCAU
CCUCACUAUCAUGUAAAGAAACUUAGGAUCACCUAAACCGAAGGCCUUCAAAGCCUUAAACAAGAGUUAAACCCUCUUAGUUUCUGCUAAGAUUCGCAGGACAUUACCCUGCAUCCUCUGAA
UGCAACUCAGAUGCUUUAAUUAAACUAGAACCUUUCCAACAUACUAGACAGGAGGGCUUCGAUCCCACGAUAAUGCAGUUAACAGCUACAUGCCUGAACCAACUGGCCUCUGCCUACAAGAC
UCCGGUACACAAUUAAUGUACAUCAAUGAGCUUGCAACUCACCAUGAACUUCACUACAGAGCCGAUAAGAAGAGGAAUCAAACCUCUGUAAAAAGGACUACAGCCUAACGCUUAUACACUCA
GCCAUCUUACCUGUGACAUUCGUCAACCGAUGAUUAUUCUCAACCAAUCACAAAGACAUCGGCACCCUAUACCUAAUUUUCGGUGCAUGAGCCGGAAUAGUGGGUACCGCCCUAAGCCUCCUC
AUUCGAGCAGAACUGGGCCAACCAGGCACUCUCCUGGGAGACGACCAAGUUUACAACGUAAUCGUCACAGCCCAUGCCUUCGUCAUAAUCUUUUUUAUAGUUAUACCAAUUAUAAUCGGAGG
AUUCGGAAACUGACUAGUCCCCCUAAUAAUUGGAGCACCUGACAUAGCAUUCCCCCGAAUAAACAAUAUAAGCUUCUGACUCCUACCACCAUCCUUCCUCCUACUCCUAGCCUCAUCCACAAU
CGAAGCAGGAGUAGGUACAGGAUGAACAGUGUACCCACCACUAGCCGGCAACCUGGCCCACGCUGGAGCCUCAGUCGACUUAGCUAUCUUCUCCCUACACUUAGCGGGAAUCUCCUCCAUCUU
AGGAGCAAUUAACUUCAUUACUACCGCAAUCAACAUAAAACCCCCUGCUCUCUCCCAAUACCAAACCCCCCUAUUCGUAUGAUCCGUGCUAAUCACUGCAGUCUUACUGCUCCUCUCCCUACC
AGUCCUAGCUGCAGGUAUUACCAUACUCCUAACAGACCGAAACUUAAACACCACCUUCUUCGACCCAGCAGGAGGAGGAGACCCAGUCCUAUACCAACACCUAUUCUGAUUUUUCGGACACCC
AGAAGUGUAUAUCCUGAUCCUACCAGGAUUUGGCAUCAUCUCCCACGUAGUAGCUUAUUACGCAGGGAAAAAAGAACCGUUCGGCUACAUAGGAAUAGUCUGAGCUAUACUAUCCAUCGGUU
UCCUAGGAUUCAUUGUCUGAGCACACCACAUAUUCACAGUAGGUAUAGACGUAGACACCCGAGCAUACUUUACAUCAGCCACUAUAAUCAUUGCAAUCCCAACAGGUAUCAAAGUGUUCAGC
UGACUAGCAACACUGCACGGAGGCACAAUUAAAUGGGAUCCCCCAAUACUAUGAGCCCUAGGAUUCAUCUUCCUAUUCACUAUUGGAGGGCUGACAGGAAUCGUCUUAGCAAACUCCUCACU
AGACAUCGCCCUGCACGACACUUACUACGUAGUAGCUCACUUCCACUACGUCCUCUCCAUAGGAGCAGUAUUCGCCAUCCUAGCAGGAUUCACCCACUGAUUCCCACUAUUCACCGGAUACAC
CCUACACUCCACAUGAGCUAAAACCCAAUUCGGAGUAAUAUUUGUAGGGGUAAAUCUAACCUUCUUCCCUCAACAUUUUCUAGGACUAGCCGGCAUGCCUCGACGAUAUUCAGACUACCCAGA
CGCCUACACAAUGUGAAAUGCCAUUUCCUCAGUAGGAUCAUUAAUCUCAAUAACAGCCGUAAUCAUACUAGUAUUCAUUAUCUGAGAAGCCUUCGCAUCUAAACGUGAAGUUCUUCACACUG
AACUUACAAGCACUAACAUCGAAUGAAUCCACGGCUGCCCACCUCCAUUCCACACAUUCGAAGAACCAGCCUUCGUCCAAGUCCAAGAAAGGAAGGAAUCGAACCCCCAUAUGUUGGUUUCAA
GCCAACCGCAUAUAAACCACUUAUGCUUCUUUCUCAUAAGAGACGUUAGUAAAACAAUUACAUAGCCUUGUCAAGACUAAAUUACAGGUGAAAACCCAGUACGCCUCUACCCACUAUAAUGG
CCAACCACUCACAAUUAGGCUUCCAAGACGCAUCAUCACCCAUCAUAGAAGAACUAAUCCAAUUCCACGACCACGCUCUAAUAGUAGCCUUAUCUAUUUGCAGCCUGGUCCUCUACCUUCUAG
CCCACAUACUUACAGAAAAACUGUCAUCAAGCACAGUAAACGCACAAGAAAUCGAACUUGUCUGAACAAUCCUCCCAGCCAUAGUCCUAAUCAUGCUCGCCCUACCGUCCCUACGAAUCUUGU
AUAUAAUAGACGAGAUCAAUGAACCAGACCUAACACUCAAAGCCAUCGGACAUCAAUGAUACUGAUCCUAUGAAUACACCGACAUCAAAAAUCUCACAUUUGACUCUUACAUAACACCCACA
ACAGACCUACCAUUAGGACACUUCCGCCUUCUAGAAGUAGACCAUCGAGUUGUAGUUCCAACAAGCUCAACAGUCCGAGUCAUCGUCACCGCUGACGAUGUACUACACUCCUGAGCCGUCCCA
AGCCUAGGUGUUAAAACUGACGCAAUCCCAGGACGCCUUAAUCAAACCUCAUUCCUAACCCCACGACCUGGAGUCUACUACGGACAGUGUUCAGAAAUCUGCGGCGCCAAUCACAGCUUUAUA
CCAAUUGUAGUAGAAGCAACCCCAUUAGCCAACUUUGAAAACUGAUCCUCUACACUAUCCUCCUAAUCAUUAAGAAGCUAUGGAACAGCACUAGCCUUUUAAGCUAGAGACAGAGGACUGCC
CCCUCCUUAAUGGUAUGCCUCAGCUAAACCCAAAUCCCUGAUUUUUUAUCAUGAUCACUUCAUGACUAGUCCUAACACUAGUCAUCCAACCCAAAUUACUAUCAUUCUUAACCACAAACCCUC
CAUCCAACAAAACCCCAACAACUACAAACACCACCCCCUGAACCUGACCAUGAACCUAAGCUUCUUUGACCAAUUUUCAAGCCCAUCCCUCCUAGGCAUCCCGUUAGUUCUCAUCGCAAUAGU
AUUCCCAGCCCUACUAAUCCCAUCCCAGGACAACCGAUGAGUAACCAACCGAUUAUCCACCCUCCAACUAUGACUGGUUAAUCUAAUUACAAAACAACUAAUGAUACCAUUAAACGAAAAAGG
CCACAAAUGAGCUCUAAUCCUAACAUCAUUAAUAAUGUUCCUUCUACUGACAAAUCUGCUAGGUCUCCUCCCAUACACAUUCACCCCAACCACUCAACUAUCCAUAAACCUAGCACUAGCCUU
CCCACUAUGACUAGCCACUCUACUAACAGGACUACGAAACCAACCAUCCCUCUCACUAGCCCAUCUACUUCCAGAAGGUACCCCAACACCACUAAUCCCUGUCCUAGUUCUAAUUGAAACAAC
CAGCCUCCUUAUUCGUCCACUAGCCUUAGGAGUACGACUAACAGCCAACUUAACAGCAGGACACCUUCUCAUUCAACUAAUCUCCACUGCCACAAUAGUUCUAUUCUCAACGAUACCAACAGU
CUCGCUACUAACCAUCCCAAUUCUCUUCUUACUAACAAUCUUAGAAGUGGCAGUAGCUAUAAUCCAAGCCUACGUAUUCGUACUCCUCCUAAGCCUCUACCUACAAGAAAACAUCUAAUUCAC
CCAAACAAUGGCCCACCAAGCACACUCUUAUCAUAUAGUAGACCCAAGCCCAUGGCCCAUUUUUGGAGCCGCCGCCGCCCUCCUUACUACUUCAGGCCUGACCAUAUGAUUCCAUUAUAACAC
CCCAUACCUCCUAAUCAUAGGCCUAACAUCCACAAUCCUAGUCAUAUUCCAAUGAUGACGAGACAUCGUACGAGAAAGCACGUUCCAAGGACAUCACACCCCCACAGUCCAAAAAGGCCUACG
UUACGGCAUGGUCCUGUUCAUCACAUCCGAAGCCUUCUUCUUCCUGGGCUUCUUCUGAGCCUUCUUCCAUUCAAGCCUAGCCCCAACCCCAGAACUAGGAGGACAAUGACCUCCAGUAGGAAU
UAAACCCCUAAAUCCAAUAGAAGUCCCACUUCUAAAUACAGCUAUCCUCCUGGCUUCAGGCGUUACAGUUACAUGGGCCCACCACAGCAUCACAGAAGCCAACCGAAAACAAGCAAUCCAAGC
UCUCACCCUAACUGUCCUUCUAGGACUUUACUUCACUGCCCUCCAGGCCAUGGAAUAUUACGAAGCCCCAUUUUCCAUCGCUGACGGAGUAUACGGCUCAACCUUCUUCGUAGCAACAGGAUU
CCACGGUCUUCACGUAAUCAUCGGCACUACAUUCCUUCUAGUGUGCCUCCUACGCUUAAUCAAAUACCACUUCACAUCAAACCAUCAUUUCGGCUUCGAAGCAGCAGCAUGAUACUGACACUU
CGUAGAUGUCGUCUGAUUGUUCCUCUACAUCUCUAUCUACUGAUGAGGAUCUUACUCUUCUAGUAUAUUUAUUACAAUCGACUUCCAAUCCUUAAAAUCUGGUUCAACCCCAGAGAAGAGUA
AUGAACAUAGUCCUAUUUAUGAUCGCCUUGUCUCUAACCCUAAGCAUCGCCCUAACCACCCUAAACUUUUGGCUCGCCCAAAUAAACCCAGACUCAGAAAAACUAUCCCCAUACGAAUGCGGC
UUCGACCCCCUAGGCUCUGCCCGCCUCCCAUUCUCAAUCCGUUUCUUCCUAGUAGCAAUCCUAUUCUUACUUUUCGACCUAGAAAUCGCCUUAUUACUCCCCCUCCCCUGAGCCGUGCAACUAG
AAUCACCUACCACCACACUAAUCUGAGCCUCCACCAUUAUCGCCCUACUAACCCUAGGACUCAUCUACGAAUGAACCCAAGGAGGACUAGAAUGAGCAGAGUAAAGAAAGUUAGUCUAACCAA
GACAGUUGAUUUCGACUCAACAAAUUAUAGUUCUAACCCUAUAACUUUCUUUAUGACAUACCUCCACCUAAGCUUCUUCUCCGCAUUCACCCUAAGCAGCCUAGGACUAGCCUUUCACCGAAC
CCACCUAAUUUCAGCUCUCCUAUGCCUAGAAAGUAUAAUAUUAUCUAUAUACAUCGCCCUGGCCAUAUGACCAAUCCAGACCCAGACAACAUCACCAACACUACUACCCAUCCUAAUACUAAC
CUUUUCCGCCUGCGAAGCCGGCACAGGACUAGCCCUACUAGUAGCUUCUACUCGAACCCACGGAUCAGACCACCUUCACAACUUCAACCUACUACAAUGCUAAAAAUCAUCGUACCAACCAUU
AUACUCCUCCCCCUUACCUUCCUCUCACCUCCCAAACACUUAUGAACUAACAUUACCACGCACAGCCUACUAAUCGCCACCAUCAGCCUACACUGACUCACCCCAACCUACUACCCCAACAAAA
ACACCUCCUCGUGAACCGCAAUUGACCAAAUCUCCUCCCCCCUACUAGUAUUAUCAUGCUGACUCCUCCCCCUCAUAAUCAUAGCAAGUCAAAACCACCUAGAACUGGAACCUCUUAAUCGCA
AACGAAUCUUCGCCACAACUAUUCUCCUAGCCCAACCAUUCAUUCUAAUUGCCUUCUCAGCCUCAGAACUAAUACUUUUCUACAUCGCAUUUGAAGCCACCCUAAUCCCAACUCUAAUCCUCA
UCACACGAUGAGGAAGCCAGCCAGAGCGACUAAACGCAGGCAUUUAUCUCCUAUUCUACACACUAGCCAGCUCACUCCCCCUACUCAUUAUUAUCCUAAACCUCCACAACCAAAUCGGCACCC
UCUACCUACCAGCACUAAAACUCUCCCAUCCCACAAUAACUACCUCAUGAUCAGGACUAAUCUCAAGCCUCGCCCUCCUUCUAGCCUUUAUGGUCAAAGCCCCACUUUACGGCCUUCAUCUAU
GACUGCCUAAAGCCCACGUAGAAGCCCCCAUCGCAGGCUCCAUACUACUAGCUGCCCUCCUACUAAAACUAGGAGGAUAUGGCAUUAUACGAGUCACUAUCCUGGUAAACCCCGCACUAAACA
ACAUACACUACCCCUUUAUUACACUAGCCCUAUGGGGAGCUGUCAUAACCAGUGCCAUUUGCCUACGACAAAUCGACCUUAAAUCACUAAUCGCCUACUCAUCCGUCAGCCACAUAGGCCUAG
UAGUAGCCGCAACUAUAAUCCAAACCCAAUGAGCCUUUUCAGGGGCUAUAAUCCUAAUAAUUUCCCAUGGCCUAACUUCUUCAAUACUAUUCUGCCUAGCUAACACCAACUAUGAACGAACCC
ACAGCCGAAUCCUACUUCUGACCCGAGGACUUCAGCCCCUACUUCCACUAAUAGCCAUCUGAUGACUCUUAGCCAACCUAACAAACAUAGCCCUUCCUCCAACAACCAACCUGAUAGCAGAAC
UAACAAUUAUAGUGGCUUUAUUUAACUGAUCUUCGAUCACAAUCAUCCUAACAGGCACCGCCAUCCUACUAACUGCCUCAUACACCCUAUACAUACUCACAAUAACACAACGAGGCACACUCC
CACCACACAUCACAUCAAUCCAAAACUCCUCAACACGAGAACACCUCCUCAUAGCCCUACACGUAAUUCCCAUAAUCCUCCUCAUCCUAAAACCUGACCUUAUUUCAGGCAUCCCAAUAUGCA
GGUAUAGUUUUAACCCAAACAUUAGACUGUGAUCCUAAAGAUAGAAGUUAGACUCUUCUUACCUGCCGAGGGGAGGUUAAACCAGCAAGAACUGCUAACUCUUGCAUCUGAGUAUAAAACCU
CAGCCCCCUUACUUUCAAAGGAUAACAGUAAUCCAAUGGUCUUAGGAGCCACCCAUCUUGGUGCAAAUCCAAGUGAAAGUAAUGGAUCUGCCACUAACCCUAAACACCCUAAUACUACUAACC
CUUGCCAUUCUAUUCACCCCAAUUAUCUUCCCAAUACUAUCCAACAAACUCAAAAACUCCCCUACCAUCAUCACAAGCACAGUUAAAACCUCAUUCCUAAUUAGCCUAGUCCCAAUAGCAAUC
CACAUCUACUCAAGUACAGAAAGCCUAAUUUCCAUCUGAGAAUGAAAAUACAUCAUAAACUUCAAAAUCCCAAUUAGCCUAAAACUAGACUUCUACUCACUCACCUUCUUCCCAAUCGCACUA
UUCGUAUCCUGAUCCAUUCUACAAUUCGCAACAUGAUACAUAGCAUCAGACCCACACAUUACAAAAUUCUUCACCUACCUCCUAUUUUUCCUUAUCGCCAUACUUAUCCUAAUCAUCGCCAAU
AACCUAUUCGUCCUGUUCAUCGGCUGAGAAGGGGUAGGAAUUAUAUCCUUCCUACUAAUCAGCUGAUGACACGGCCGAGCAGAGGCUAAUACUGCCGCCCUACAAGCCGUACUAUACAACCG
AGUAGGAGACGUAGGACUUAUCCUCUGCAUAGCAUGACUGGCCUCCACAAUAAACACCUGAGAGAUCCAACAACUAACCUCCCCACACCAAACCCCCACACUACCCCUACUAGGCCUCAUCCU
AGCCGCAACAGGAAAAUCUGCCCAAUUCGGUCUACACCCAUGACUACCAGCUGCAAUAGAGGGCCCAACCCCCGUAUCCGCCCUACUGCACUCAAGCACAAUAGUAGUUGCCGGAAUUUUCCU
GCUAAUCCGAACCCACCCUCUAUUUAACAACAACCAAACCGCCCUCACCCUCUGCCUAUGCCUCGGCGCCCUCUCCACAUUAUUCGCAGCUACAUGCGCCCUUACUCAAAAUGACAUCAAAAAA
AUCAUUGCCUUCUCCACCUCCAGUCAACUAGGCCUAAUGAUAGUCACAAUCGGACUAAACCAACCCCAAUUAGCCUUUCUCCAUAUCUCCACCCACGCAUUCUUCAAAGCAAUACUAUUCCUA
UGCUCCGGCUCAAUUAUCCACAACCUAAAUGGGGAACAAGACAUCCGAAAAAUAGGAGGACUUCAAAAAAUACUACCAACAACAACCUCAUGCCUAACCAUUGGCAACCUAGCCCUAAUAGGC
ACACCAUUCCUUGCAGGAUUCUACUCAAAAGACCAAAUCAUCGAAAGCUUGAGCACAUCCUACCUAAACGCCUGAGCCCUACUCCUAACCCUACUAGCCACAUCUUUCACUGCAAUCUAUACA
AUACGCAUAACAGUACUAGUACAAUCAGGUUUCGUACGCACCCCUCCACUCACCCCUAUAAACGAAAACAACCCAGCCGUAAUCCUGCCCAUCACCCGACUCGCACUAGGCAGCAUCACAGCC
GGAUUUUUCAUCACCUCAUUUAUCACCCCAACAAAAACCCCCACAUUAACCAUACCAUUAUCCAUUAAACUAACGGCAAUCGUAGUUACAGCCCUAGGAAUUGUACUAGCCCUAGAAAUUACA
AAAAUGACCCAAACCCUAAUCCUAAAAAAACAAUCCACCCUAUCAAAUUUCUCAAUCUCCCUAGGCUACUUCAACCCCCUAAUACACCGUCUACAUUCAACUACCAUCCUGACCGGAGGCCAA
AAACUUGCCUCACACCUAAUCGACCUCUCAUGAUACAAACUAAUAGGCCCAGAAGGACUAGCCAACCUACAGAUAAUAGCAUCCAAAACCGCCACUACCUUACACUCAGGAUCAACAAAAGCC
UACCUAGGCUCCUUCGCCCUAUCCAUCCUUAUCAUCCUCAUAUCUACAUACAGAACCCUCCAUAAUGGCACUCAAUCUUCGUAAAACCCACCCACUAAUAAAAGUCGUCAAUGAUGCCCUAAU
CGACCUCCCAACCCCAUCAAACAUUUCAACUUGAUGAAACUUCGGGUCACUCCUAGGCAUCUGCCUAAUUACCCAAAUUGUAACCGGCCUCCUUCUAGCAACCCACUACACUGCAGACACCUC
CUUAGCCUUCACUUCAGUCGCCCACACCUGCCGAAACGUCCAAUUCGGCUGACUCAUCCGCAAUCUCCAUGCAAACGGAGCCUCAUUCUUCUUCAUCUGCAUCUACCUACACAUCGGCCGAGG
AAUCUAUUACGGCUCAUACCUAAACAAAGAAACCUGAAAUGUAGGAGUCAUCCUACUCCUGACCCUUAUAGCAACCGCCUUCGUAGGAUAUGUCCUGCCAUGAGGACAAAUAUCAUUCUGAG
GGGCCACAGUAAUUACCAACCUAUUUUCUGCAAUCCCCUACAUUGGCCAAACACUAGUAGAAUGAGCUUGAGGAGGGUUCUCAGUAGACAACCCCACACUAACACGAUUCUUCGCCCUUCACU
UCCUACUCCCAUUCCUUAUUGCCGGACUCACACUUGUUCACCUAACCUUCUUACACGAAACGGGAUCGAAUAACCCCCUAGGAAUCCCCUCAGACUGCGACAAAAUCCCAUUCCACCCAUAUU
ACACCACAAAAGACAUUCUAGGCUUUGCCAUCAUACUAAUCCUACUUACAGCCAUAGCACUAUUCUCCCCAAACAUACUAGGAGACCCAGAAAACUUCACCCCAGCCAACCCUCUAGUUACAC
CUCCACACAUCAAACCUGAAUGAUACUUCCUAUUCGCAUACGCCAUCCUACGAUCAAUCCCAAACAAACUAGGAGGUGUACUGGCCCUUGCCGCCUCCGUCCUAGUCCUAUUCCUCUUACCCC
UACUCCACACAUCCAAACUACGCUCUAUAACCUUCCGACCACUAUCACAAAUCCUAUUCUGAACCCUCGUAGCUGACCUCCUCAUUCUUACCUGAGUAGGCAGCCAACCAGUCGAACAUCCCU
UCAUCAUCAUCGGACAGCUAGCCUCCCUAGCCUACUUCACAAUUAUUCUAGUCCUACUCCCACUCGCCUCCAUCCUAGAGAACAAACUCCUAAAACUUUAACAGACUCUAAUAGUUUAUUAAA
ACAUUGGUCUUGUAAGCCAAAGAUUGAAGAUUACACCCCUUCUUAGAGUUUCGCGUCUCAGAAAGAAAGGAAUCAAACCCUUAUCACCAACUCCCAAAGCUGGAAUUUUAAUUAAACUACUU
UCUGGUCACUACCCUAAACAGCCCGAAUCGCCCCCCGCGACAACCCUCGUACUAACUCAAGUACUACAAACAAAGUUAGCAACAACCCCCACCCCCCAAUUAAAAACAACCCUACUCCGUCUGA
AUAAAAACCCGCCGCUCCACCAAAGUCCGUACGAACCAUAGAAAGCCCCCCACCAUUCACCGUACCACUAUCCACAACCGACCCAAGACCACCCCACACAACAACCCCUACAACAACAACUAAC
CCCAUCCCCAACCCAUAACCAACAACCCCUCAAUCCCCCCAUGUCUCAGGGUACGGAUCUGCAGCCAAAGACACUGAAUACACAAACACCACCAACAUACCACCUAAAUAAACCAUAACCAGCA
CCAAAGACACAAAAGAAACCCCCAAACUCACCAGUCACCCACACCCAGCAACAGACGCCAAGACUAAUCCUACAACCCCAUAAUAAGGAGAAGGAUUAGACGCCACCCCCAACCCCCCUAAAAC
GAGACACAGCCCUAAAAAUACUACAAAUUCUAUCAUAAUUCCAGCCUGGCCUCUCUCCAGGAUCAACGACCUGAAAAGUCGUCGUUAUUAGAAAUUUAACUACAGGAACCCCCCCCCCCUUCC
CCCCCCAACAUGUUUCCUCAUGUUUUCUCAUGUUUUUUCUGUUAUGUGGUUCUGCAUCGCUCUCUUUAGCACAUCAGACAACUACUAUAAUGUAGGAUACUCCACGCCAUACGUAUUGCCUU
GCCUCCAAAACCUCAAACAUUAUCUCCCAUGAGAUAAUUUGCGAGCUAUUACAGUUCUAGGGACUUCUUUGUUUCAGGUACCAUUAACCCAAGUGAUCCUACCUCCAGCCGGAGCCGCAAGCG
UUACUUAAGUUCGACUAUAUCUCCCUGCGCCUAAAUUCCUUUCCUCAGGAUACGACUAAUAUCCUAGUACACCUUUGCAUUCACCUAGUCACGCACUUCGCCCACCUCCUAGGAUAUAUCCCU
CUCCAACAGCCUUCAGGAACUCCCAAGCCAGAGAACCUGGUUAUCUAUUAAUCGUGUUUCUCACGAGAACCGAGCUACUCGACGUCAGUUAUACCUUCGGUUAUUGGUGUCAGGGGCAUACA
UCUAAUAAACUUGAUCUCCAACGUGCCACCGGUUGUAAUUUCAGGAACCCUACUCGCCUAAUUUCUAAUCAAUUGCUCUUCACAGAUACAUAUGCUUGGGGAUGGACGCUCCUCAUAAAUAU
CCGUAAUCGCGGCUAGCCAUAGGCCGUUUUAGCUCUUCUUUUCUUUCUGGGGUCUCUUCAAUAAGCCCUUCCAGUGCGUAGCAGGAGAUAUCUUCCUCUUGACAUGUCCAUCACAUGACCGGC
GAACAUACGUCUGCCCGAAACCACUUGGAAUGUCAUGGUUUGUGGAAUAAGUAGACCAACUUUGACACUGAUGCACUUUGACCGCAUUCAUGGGAUCCGCGCCAUUUACCUCUUACAAGUAG
CAGAUAGUGUAAUGGUUGGCAGGCAUACUAAUUUAUUUGUCUUCUUCUAGGAUUUGUCACCUAAACCCCGUUUUUUUCAUUUUUUUUUCAUUUUUUUUCUUUUUUGUUUGUCAUUUUUCGU
UCGCUUUAAACAAACCAAUAGCUAUAUAACCCUACAUUUUCACAAAUUUUUUGUCAUCAAUUAGUUUAACAACAAACUUUCCUCCAACAUUCCCCCAAACACAAACUAACCAUCCACCAUCAC
UUUAACAACAUUUUAACAAACAAAACCACUCAAACAAACUGUACAAAUCCAGCAACAUUCACCCAACCCAAAAACCAAACAAAAAUAUAAAACAGUAACACAAAACAGCCAACAACUUCCCAG
CACUAAU
Aminoacidos del Trepador Pechiblanco
VPVA*KKHDTEDVKMVASCTQGQKT*S*PYC*LLLGIYMRVSALQCRCPGHPDLR*IGAGIRLTILVAQDALQLPHPHGSSAVVNIKQ*V*T*LSHSNIRAGQSCASHRGHTGGPN*HYNGVKRGSTLSE*LRL
KGY*AVISPRNP*DHFYKRKS*SNDQLKSTKARAQTGIRYPTMPGPKS*CFILPKHPPENYEH*RLKL*GLGGAPNPPRGACSVIDDPRYYLTISRTISLHTAVSSSPTLKAQQ*AQ*PTPLVRQVKV*PMGWK*W
ATFSIIEHTAKGFETVPGRRI*Q*SGTIEPSLSRLWDTYIPPVTLLKGDQHHYN**TIQPKMRQVVTR*VYRKVHLEHQDVA*LKHSAYT*KMSVNHRSS*CQTLAQQT*PRITKSLTTPKQSIYKSQYRR*KRHH
WSDRDYVP*GKDEITVNNIS*KKQRSTLVPFA*WSSKKNQAK*ILVCHPETQASYSRAAIIERTRLCCKRVG*LVSRGEKPIELGDSWLPVKRI*VHS*FSSKETQQTLMKRIKGYLKGVQLL*KRIQSPRADK*P
HQTYLWALKQPSTKSALKLSTTKIYNPYESLLTNRLTYTQIGELMLE*VTRVLPLRRKLTSAHY*QITSIR*IKQAQY*VYC*PDRGASIKKD*NL*KELGKLSRPDCLPKT*PSANHIQVLKVMPAQ*PNV*RPR
YPNRAKVAQSIVP*IETSMNG*TRS*LSLTGNR*N*SPCAKAGIKP*DEKTLWNFKISGHPKLPTHPPGSHHTNCWPAFFGWGDLGEKQILQKLDHTSRLRATPQRANSNQTQYN*SMDQATPGITAQSPPRVHI
DEEVYDLDVGSGHPSGAAATKGSFVQRLTVLRDLSSDRSNPGRFLSMTSSSQYERIGKARPIPQASLRPK**NQLNYERPSHQPRPRKGQASVAELGKCKRLKSFKSEVQILSLAATPND*LPTTNQPNYSPLLR
PAHFNRSSLSHVSRTQNPQLHAKPKRPKYRRTIRTTTTPSRRGKTIHQRAHPPINILSYPIYCNSNTSPFTRNLNLNSPSPSIPTSRSKPRPTIPAGHVKLSSLLNSMIRMSLQLKIRPNRSPTSSSSNHFL*SYPSNYP
IINYPTNRELYPQLHINRSRTTISHLLLLTPSHNMIRIYIS*NKPSPIRPYRRGI*TSIRI*RRICSRTIRLILPSRIC*HYTYKHTNRYPILQPKHTQPTPRIIPHNPCHKNPPTLRRIPMNSCLIPTIPIRSVNAPIMKKLSPP
NTGTMPMTYQHANFLCRPPSTSITPRKCA*TLKGHYDKVNIEVYQPSHFLPN*KSRN*TYTRGIKTLYTSLILFSTTAGSAK*AIGPIPRK*WFNPFPC**TPKQNWSSPLAYSWEPPLQSQATTES*LEQA*KSTL
*PFSP*SQNHTTPAPSKPQPSTF*YKQQPQPYSYSRA*PMPGTQDNGILPN*HTPPHA*FLPQPLQSN*A*YHSTSDSQKYFKAPHSPQASYYQQQ*NSHQLHYYS*PLNH*IQPC*LL*PSYPQP*EDE*A*TKHKP
ERS*PFPPSLT*AE*PLSSHTAQNSPY*TSTYTPS*PQPYSSP*TQ*KSLNYLP**PHEQNHQH*AQPYC*HFYL*QASPL*QDSSQNDSLFKN*PNKKYL**QQRSHYCPY*AYFSTYV*HTARQLHFPHTLQTT*N
DGTPTNPLTPKSPS*LPCPSYSSPSLPSSSLSCKET*DHLNRRPSKP*TRVKPS*FLLRFAGHYPASSECNSDALIKLEPFQHTRQEGFDPTIMQLTATCLNQLASAYKTPVHN*CTSMSLQLTMNFTTEPIRRGIKP
L*KGLQPNAYTLSHLTCDIRQPMIILNQSQRHRHPIPNFRCMSRNSGYRPKPPHSSRTGPTRHSPGRRPSLQRNRHSPCLRHNLFYSYTNYNRRIRKLTSPPNNWST*HSIPPNKQYKLLTPTTILPPTPSLIHNRSR
SRYRMNSVPTTSRQPGPRWSLSRLSYLLPTLSGNLLHLRSN*LHYYRNQHKTPCSLPIPNPPIRMIRANHCSLTAPLPTSPSCRYYHTPNRPKLKHHLLRPSRRRRPSPIPTPILIFRTPRSVYPDPTRIWHHLPRSS
LLRREKRTVRLHRNSLSYTIHRFPRIHCLSTPHIHSRYRRRHPSILYISHYNHCNPNRYQSVQLTSNTARRHN*MGSPNTMSPRIHLPIHYWRADRNRLSKLLTRHRPARHLLRSSSLPLRPLHRSSIRHPSRIHPLI
PTIHRIHPTLHMS*NPIRSNICRGKSNLLPSTFSRTSRHASTIFRLPRRLHNVKCHFLSRIINLNNSRNHTSIHYLRSLRI*T*SSSH*TYKH*HRMNPRLPTSIPHIRRTSLRPSPRKEGIEPPYVGFKPTAYKPLMLLS
HKRR**NNYIALSRLNYR*KPSTPLPTIMANHSQLGFQDASSPIIEELIQFHDHALIVALSICSLVLYLLAHILTEKLSSSTVNAQEIELV*TILPAIVLIMLALPSLRILYIIDEINEPDLTLKAIGHQ*Y*SYEYTDIKN
LTFDSYITPTTDLPLGHFRLLEVDHRVVVPTSSTVRVIVTADDVLHS*AVPSLGVKTDAIPGRLNQTSFLTPRPGVYYGQCSEICGANHSFIPIVVEATPLANFEN*SSTLSS*SLRSYGTALAF*ARDRGLPPP*W
YASAKPKSLIFYHDHFMTSPNTSHPTQITIILNHKPSIQQNPNNYKHHPLNLTMNLSFFDQFSSPSLLGIPLVLIAIVFPALLIPSQDNR*VTNRLSTLQL*LVNLITKQLMIPLNEKGHK*ALILTSLIMFLLLTNLLG
LLPYTFTPTTQLSINLALAFPL*LATLLTGLRNQPSLSLAHLLPEGTPTPLIPVLVLIETTSLLIRPLALGVRLTANLTAGHLLIQLISTATIVLFSTIPTVSLLTIPILFLLTILEVAVAIIQAYVFVLLLSLYLQENI*FT
QTMAHQAHSYHIVDPSPWPIFGAAAALLTTSGLTI*FHYNTPYLLIIGLTSTILVIFQ**RDIVRESTFQGHHTPTVQKGLRYGMVLFITSEAFFFLGFF*AFFHSSLAPTPELGGQ*PPVGIKPLNPIEVPLLNTAILL
ASGVTVTWAHHSITEANRKQAIQALTLTVLLGLYFTALQAMEYYEAPFSIADGVYGSTFFVATGFHGLHVIIGTTFLLVCLLRLIKYHFTSNHHFGFEAAA*Y*HFVDVV*LFLYISIY**GSYSSSIFITIDFQSLK
SGSTPEKSNEHSPIYDRLVSNPKHRPNHPKLLARPNKPRLRKTIPIRMRLRPPRLCPPPILNPFLPSSNPILTFRPRNRLITPPPLSRATRITYHHTNLSLHHYRPTNPRTHLRMNPRRTRMSRVKKVSLTKTVDFDS
TNYSSNPITFFMTYLHLSFFSAFTLSSLGLAFHRTHLISALLCLESIILSIYIALAI*PIQTQTTSPTLLPILILTFSACEAGTGLALLVASTRTHGSDHLHNFNLLQC*KSSYQPLYSSPLPSSHLPNTYELTLPRTAY*S
PPSAYTDSPQPTTPTKTPPREPQLTKSPPPY*YYHADSSPS*S*QVKTT*NWNLLIANESSPQLFS*PNHSF*LPSQPQN*YFSTSHLKPP*SQL*SSSHDEEASQSD*TQAFISYSTH*PAHSPYSLLS*TSTTKSAPST
YQH*NSPIPQ*LPHDQD*SQASPSF*PLWSKPHFTAFIYDCLKPT*KPPSQAPYY*LPSY*N*EDMALYESLSW*TPH*TTYTTPLLH*PYGELS*PVPFAYDKSTLNH*SPTHPSAT*A***PQL*SKPNEPFQGL*S*
*FPMA*LLQYYSA*LTPTMNEPTAESYF*PEDFSPYFH**PSDDS*PT*QT*PFLQQPT**QN*QL*WLYLTDLRSQSS*QAPPSY*LPHTPYTYSQ*HNEAHSHHTSHQSKTPQHENTSS*PYT*FP*SSSS*NLTLFQ
ASQYAGIVLTQTLDCDPKDRS*TLLTCRGEVKPARTANSCI*V*NLSPLTFKG*Q*SNGLRSHPSWCKSK*K*WICH*P*TP*YY*PLPFYSPQLSSQYYPTNSKTPLPSSQAQLKPHS*LA*SQ*QSTSTQVQKA*F
PSENENTS*TSKSQLA*N*TSTHSPSSQSHYSYPDPFYNSQHDT*HQTHTLQNSSPTSYFSLSPYLS*SSPITYSSCSSAEKG*ELYPSY*SADDTAEQRLILPPYKPYYTTE*ET*DLSSA*HDWPPQ*TPERSNN*PP
HTKPPHYPY*ASS*PQQENLPNSVYTHDYQLQ*RAQPPYPPYCTQAQ**LPEFSC*SEPTLYLTTTKPPSPSAYASAPSPHYSQLHAPLLKMTSKKSLPSPPPVN*A***SQSD*TNPN*PFSISPPTHSSKQYYSYAP
AQLSTT*MGNKTSEK*EDFKKYYQQQPHA*PLAT*P**AHHSLQDSTQKTKSSKA*AHPT*TPEPYS*PY*PHLSLQSIQYA*QY*YNQVSYAPLHSPL*TKTTQP*SCPSPDSH*AASQPDFSSPHLSPQQKPPH*P
YHYPLN*RQS*LQP*ELY*P*KLQK*PKP*S*KNNPPYQISQSP*ATSTP*YTVYIQLPS*PEAKNLPHT*STSHDTN**AQKD*PTYR**HPKPPLPYTQDQQKPT*APSPYPSLSSSYLHTEPSIMALNLRKTHPLIK
VVNDALIDLPTPSNIST**NFGSLLGICLITQIVTGLLLATHYTADTSLAFTSVAHTCRNVQFG*LIRNLHANGASFFFICIYLHIGRGIYYGSYLNKET*NVGVILLLTLIATAFVGYVLP*GQISF*GATVITNLFSA
IPYIGQTLVE*A*GGFSVDNPTLTRFFALHFLLPFLIAGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYTTKDILGFAIILILLTAIALFSPNILGDPENFTPANPLVTPPHIKPE*YFLFAYAILRSIPNKLGGVLAL
AASVLVLFLLPLLHTSKLRSITFRPLSQILF*TLVADLLILT*VGSQPVEHPFIIIGQLASLAYFTIILVLLPLASILENKLLKL*QTLIVY*NIGLVSQRLKITPLLRVSRLRKKGIKPLSPTPKAGILIKLLSGHYPKQPE
SPPATTLVLTQVLQTKLATTPTPQLKTTLLRLNKNPPLHQSPYEP*KAPHHSPYHYPQPTQDHPTQQPLQQQLTPSPTHNQQPLNPPMSQGTDLQPKTLNTQTPPTYHLNKP*PAPKTQKKPPNSPVTHTQQQT
PRLILQPHNKEKD*TPPPTPLKRDTALKILQILS*FQPGLSPGSTT*KVVVIRNLTTGTPPPFPPQHVSSCFLMFFLLCGSASLSLAHQTTTIM*DTPRHTYCLASKTSNIISHEIICELLQF*GLLCFRYH*PK*SYLQP
EPQALLKFDYISLRLNSFPQDTTNILVHLCIHLVTHFAHLLGYIPLQQPSGTPKPENLVIY*SCFSREPSYSTSVIPSVIGVRGIHLINLISNVPPVVISGTLLA*FLINCSSQIHMLGDGRSS*ISVIAASHRPF*LFFSF
WGLFNKPFQCVAGDIFLLTCPSHDRRTYVCPKPLGMSWFVE*VDQL*H*CTLTAFMGSAPFTSYK*QIV*WLAGILIYLSSSRICHLNPVFFIFFSFFFFFVCHFSFALNKPIAI*PYIFTNFLSSISLTTNFPPTFPQT
QTNHPPSL*QHFNKQNHSNKLYKSSNIHPTQKPNKNIKQ*HKTANNFPAL
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