dye (arc) mutants: insights into an unexplained phenotype and its

Anuncio
CORRIGENDUM
dye (arc ) mutants: insights into an unexplained phenotype and its
suppression by the synthesis of poly (3-hydroxybutyrate) in
Escherichia coli recombinants
Jimena A. Ruiz1, Rubén O. Fernández2, Pablo I. Nikel3, Beatriz S. Méndez1 & M. Julia Pettinari1
1
Departamento de Quı́mica Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina; 2Departamento
de Radiobiologı́a, Comisión Nacional de Energı́a Atómica, San Martı́n, Argentina; and 3Instituto de Investigaciones Biotecnológicas, Universidad
Nacional de General San Martı́n, San Martı́n, Argentina
First published online May 2006.
doi: 10.1111/j.1574-6968.2006.00296.x
One of these regulatory systems, the ArcAB two-component signal transduction system, modulates the expression
of many operons according to the redox conditions of
growth at the transcriptional level (Lynch & Lin, 1996).
ArcB is a transmembrane sensor kinase, which under low O2
concentration conditions undergoes autophosphorylation
and then transphosphorylates the response regulator ArcA,
one of the global regulators in Escherichia coli (Georgellis
et al., 2001). The main targets for repression by the
phosphorylated regulator are the genes that code for the
2006 Federation of European Microbiological Societies
Published by Blackwell Publishing Ltd. All rights reserved
c
enzymes involved in aerobic respiration, such as those of the
tricarboxylic acid cycle. On the other hand, in low O2
conditions ArcA activates respiratory chain enzymes such
as the cytochrome d oxidase, with high affinity for O2, and
fermentation enzymes such as pyruvate-formate lyase
(Lynch & Lin, 1996).
References
Georgellis D, Kwon O & Lin ECC (2001) Quinones as the redox
signal for the arc two-component system of bacteria. Science
292: 2314–2316.
Ruiz JA, Fernández RO, Nikel PI, Méndez BS & Pettinari MJ
(2006) dye (arc) mutants: insights into an unexplained
phenotype and its suppression by the synthesis of poly
(3-hydroxybutyrate) in Escherichia coli recombinants. FEMS
Microbiol Lett 258: 55–60.
FEMS Microbiol Lett 259 (2006) 332
Downloaded from http://femsle.oxfordjournals.org/ by guest on November 20, 2016
In the Introduction to the article by Ruiz et al. (2006), some
references were omitted. Part of the Introduction is reproduced correctly below, beginning at line 10. One of these
references (Georgellis et al., 2001) was omitted from the
reference list in the original article and is shown in full
below. The authors apologize for this error.
Descargar