Acknowledgements Here we are again at another turning point in my life and career. This has been an exciting and fulfilling process of attaining acknowledge, artistic creation and, as well as, self-discovery. Undoubtedly, all this could not have been possible to achieve without the invaluable help of many people. Most of them who collaborated to get this enterprise come to an end are formally mentioned at the end of each chapter. However, this is of course not enough. First of all, I would like to express my gratitude to all my promotors and supervisors (in Groningen and San Luis), who supported me, guided my projects and respected my ideas from the very beginning. I especially want to thank Paul and Daniel for believing in my “crazy computational” approaches, giving me the time and place to carry them out, and always making sure that I stay busy no matter what. Also, I thank Uli and Siewert-Jan because without their guidance and continuous support none of this would have been possible. Your long hours and dedication are greatly appreciated. The whole staff of the Molecular Neurobiology group has, somehow and at the right time, given its contribution which is also valid for the entire Department of Animal Physiology. Secretaries, technicians, Master students, PhD students and Professors must know that I am fully grateful for your help. Moreover, it’s very gratifying to realize that my cultural and scientific background has been substantially enlarged by working with such a nice group of people. Thank you to the entire department. Special thanks to Ivi, Niki and Pieter for the great time at work and also for the unforgettable “Nirvana, Salsa, Merengue” moments. I want to give a big thank you to Paulien for those great moments that we shared from the very beginning. I would also like to express my gratitude to the people who warmly welcomed me in Hungary. I really appreciate the support that the groups of Prof. Penke and Prof. Viskolcz have offered me during my stay in Szeged. Also, I am very grateful to Csaba who did not only guide me in my first steps into peptide synthesis, but also received me as a member of his family. My deepest appreciation to Prof. Csizmadia, aka IGC. You have been not only my mentor, but also a source of inspiration. During my first visit to Szeged I was very lucky to meet a formidable person, Mr. Izsák, who soon became one of my dearest friends since then. Robi, I don’t know if I would be able to show my appreciation by writing or saying these simple words. However, if something is sure it’s that your scientific, artistic, and personal inputs are invaluable to me. Köszönöm szépen! I would like to extend my sincere appreciation and thanks to the always active community of dancers and dance-related people of Groningen who contributed to the success and failure of my inner and outer artistic being. I can’t avoid the need of expressing my most sincere gratitude to Random Collision, especially 155 acknowledgements to Kirsten and Edan. Thank you guys. From this tiny, but yet rich dance world, I want to especially thank to Helena, aka Ms. Volkov. More than expressing my gratitude I should apologize for using, and sometimes abusing Ms. Volkov’s intellectual, physical, and spiritual beauty as an infinite source of inspiration. I deeply appreciate your presence in my life. Jose, Jacek, Vincent, Wojtek, Anthony, Tomek, Caroline and Glenn are the people who created a fun and very enjoyable ambience not only in Groningen but also in every city of Europe where we have expended some time together. Thanks guys! En cuanto a la gente que deje en Argentina, lo mínimo que puedo hacer es agradecerles toda la ayuda prestada desde mis primeros pasos en investigación en el gropu de Modelado Molecular hasta mis primeras experiencias docente en la cátedra de Química General. Así es que quiero agradecer a todos mis colegas de la UNSL. Especialmente quiero agradecer a Miguel, Ana y Sebastián. La verdad es que sin Uds. todo esto habría sido imposible de realizar. Por allí en Mendoza, Dora, Mabel, Edith y Miguel son y siempre lo fueron mi primera y principal plataforma de despegue. Sin Uds. yo hoy no estaría escribiendo estas palabras. Gracias por todo! Gerardo, Vero y Alma. Les agradezco infinitamente por todo el amor y cariño dado. Por cuidar a Thorio, por haberme convertido en el tío más feliz del mundo y sobre todo por ser mi plat- 156 aforma de aterrizaje cuando el volar se me hace pesado. Miles de gracias por estar siempre ahí. Mamá, vos sos la fuerza hecha mujer, tantas cosas que has tenido que hacer por mí, te estoy infinitamente agradecido. Si algo aprendí de vos y el Papá es que debo luchar y trabajar duro por lo que quiera hacer de mi vida, por mis sueños. Y acá estoy terminando otra etapa en mi vida gracias a vos. Esta tesis también va dedicada a vos. Claro está que no puedo dejar de agradecer a todos los Argentos que han hecho de Groningen una “klein Argentinië”. Euge, Maxi, Juan, Casper (por adopción) y Marina son mi cable a tierra, o mejor dicho el cable a mi tierra. En cuanto a Marina, que te puedo decir?!, sos lo más piba. No sé como agradecerte todo lo que me has ayudado y bancado desde que estoy en Holanda. Desde la bici de la prehistoria que me prestante cuando vine por primera vez, los mates compartidos, las tardes de gym, los asados y hasta las noches en vela por tus (benditos) experimentos. La verdad es un gustazo haberte conocido. Ik wil graag mijn dank uitspreken aan Maarten en zijn familie (de hele Wieringa en Zijlstra families), die al snel mijn Nederlandse familie zijn geworden. Jullie hebben een extra gezellig Groningen voor me gecreëerd. Hartelijk bedankt voor jullie steun. Finally, because it’s nearly impossible to mention here everyone who has in one way or another helped me during my PhD adventure, I give you my most sincere thank y’all! ■ 157