CTAHOBIIll(E

CTAHOBIIll(E
OT Yfl . KOp. ITpOcP kP BaHbO I1BaHoB MineB ,UM, ,U6H, PbKOBO,UHTefl Ha KaTe,Upa Me,UHUHHCKa XHMH5I H 6HOXHMH5I, Me,UHUHHCKH <DaKYflTeT, Me,UHUHHCKH YHHBepCHTeT - COCPH5I OTHOCHO ,UHCepTaUHOHHH5I TPY'u "TeYHO-XpOMaTorpacPCKH MeTO,UH 3a Onpe,Uefl5lHe Ha aMHHOKHCeflHHH H nOflHaMHHH Ype3 ,UepHBaTH3aUH5I C 9-cpflyopeHHflMeTOKCHKap6oHHflHa rpyna " 3a npHCb)l{,UaHe Ha 06pa30BaTeflHaTa H HaYYHa CTeneH ",UOKTOP" B 06flaCT Ha BHCllIeTO 06pa30BaHHe
4.
ITPHP0,UHH Hay KH, MaTe~1aTHKa H HHcPopMaTHKa, ITpocPecHoHaJJHO 4.3
HanpaBfleHHe
bHOflOrHyeCKH HayKH H HaYYHa cneUHaJJHOCT "bHOXHMH5I" Ha BaJJeHTHH CTOHyeB JI03aHoB, KaTe,Upa no Me,UHUHHcKa XHMH5I H 6HOXHMH5I, Me,UHUHHcKH cPaKYflTeT, Me,UHUHHcKH YHHBepcHTeT - COcPH5I r -H
BaJJeHTHH JI03aHoB e ,UoKTopaHT Ha caMOCT05lTeflHa no,UrOTOBKa B KaTe,UpaTa no
Me,UHUHHcKa XHMH5I H bHOXHMH5I Ha Me,UHUHHcKH5I cPaKymeT npH MY-COCPH5I. B . JI03aHoB
e
po,UeH
npe3
1959
r.,
3aBbplliBa
BHcweTO
CH
06pa30BaHHe
BbB
BHCWH5I
XHMHKO­
TeXHOflorWleH HHCTHTYT B COCPH5I (cera YXMT) npe3 1985 r.CbC cneUHaJJHOCT HH)I{eHep­
XHMHK
B
o6flacTTa
Ha
CPHHHH5I
OpraHHyeH
CHHTe3.
Bnocfle,UcTBHe
e
pa60THfl
KaTO
H3Cfle,UOBaTefl y Hac H B YY)I(6HHa (ICEGB TpHecT, I1TaJJH5I) B o6flacTHTe Ha 6HOpraHHYHH5I H
nenTH,UeH CHHTe3 H aHaJJH3. OT eceHTa Ha 1997 pa60TH KaTO cneUHaJJHCT XHMHK B KaTe,UpaTa
no
Me,UHUHHCKa
XHMH5I
H
6HOXHMH5I.
B
KayeCTBOTO
CH
Ha
HerOB
,UbflrorO,UHweH
a,UMHHHcTpaTHBeH, a nOHaCT05lIUeM H HayyeH PbKoBo,UHTefl, CYHTaM 3a BCI)KHO ,Ua oT6efle)Ka,
ye npe3 ueflH5I ITepHo,U Ha pa60TaTa CH B KaTe'upaTa r-H B. JI03aHoB e nOKa3BaJJ 3aBH,UHa
pa6oTocnoco6HoCT, aKypaTHocT H KopeKTHOCT B ,UeHcTBH5ITa CH. B
MOMeHTa B. JIo3aHoB
YMeflO PbKOBO,UH fla6opaTOpH5I " AHaJJH3 H CHHTe3 Ha 6HoaKTHBHH BeIUecTBa" B KaTe'upaTa,
K05lTO 6e Cb3,Ua,UeHa B pe3YflTaT Ha H3KflIOYHTeflHO ,UeHHo HerOBO yYaCTHe.
'uHcepTaUHOHHH5IT Tpy,U Ha r-H BaJJeHTHH JI03aHoB, npe,UCTaBeH 3a npHCb)l{,UaHeTo Ha
06pa30BaTeflHaTa H
HaYYHa
CTeneH
",UOKTOp",
e
03arfl aBeH
"Teliflo-xpoJl1amOzpa£jJcKu
Jl1emoi)u 3a onpei)eJlJlfle fla ~ltliflOKllCeJlUHU U 1l0JlUaMUfili lIpel i)epu6amllJal{llJl
£jJJlyopeuuJlJl1emOKCUKap6ouuJlua zpyna"
H
e
H3U5IflO
pa3pa60TeH
B
KaTe,UpaTa
C
9­
ITO
Me,UHUHHcKa XHMH5I H 6HOXHMH5I. 'uHcepTaUH5ITa e HaITHCaHa Ha 78 cTpaHHUH H cb,Ubp)l{a 27
qmrypH, 9 Ta6flHUH H
6
cxeMH. B pa60TaTa ca H3nOfl3BaHH 122 flHTepaTy pHH H3TOYHHKa Ha
aHrflHHcKH e3HK. 'uHcepTaUHOHHH5IT Tpy,U e cTpyKTypHpaH npaBHflHo H e npe,UcTaBeH BbB BH,U
H o6eM , oTrOBap5lIUH Ha H3HCKBaHmna Ha 3P ACPb, ITpaBHflHHKa 3a npHflQ)KeHHeTO My H
npaBHflHHKa Ha MY - C0cPH5I.
Pa60TaTa no CB05lTa CbIUHOCT e 113U5lflO MeTO,llI1'1Ha. T5I e KOHueHTp11paHa BbPXY
pa3pa60TBaHeTO
Ha
HOB11
MeTO,ll11
3a
e,llHOBpeMeHeH
aHM113
Ha
aM11HOK11Cefl11H11
11
nOfl11aM11H11, 6a311paH11 Ha 113n0J13I3aHe Ha B11COKO ecpeKT11BHa TeLlHa xpOMaTorpacp1151 Cfle,ll
npe,llBap11TeflHa ,llep11BaT113aU1151. T0311 T11n MeTO,ll11 H5IMaT ,ll11peKTHa 3a,llalfa ,L(a 113Cfle,llBaT
6HOX11M11lfH11 npOueC11, HO '-Ipe3 T5IXHOTO rrpaKTWleCKO 113rr0J13BaHe ce rrOCT11raT pe3YflTaTH,
K011TO 11MaT CB05lTa 6110X11M11lfHa, ,ll11arHOCT11'-1Ha 11 CP113HOflOrHlfHa CTOHHOCT.
JIHTepaTypHHSlT 0630p Ha pa60TaTa e Han11CaH MHoro neCTefl11BO H TOlfHO, Ha cpOHa
Ha OrpOMH1151 06eM OT HM11'-1HH ,llaHH11 B fl11TepaTypaTa. Cfle,ll KpaTKO 11 C11CTeMaT11311paHO
113flQ)KeI-me OTHOCHO CP113110flOr11lfHaTa H 6110X11M11lfHa 3Half11MOCT Ha 06eKT11Te 3a aHM113 ­
aMHHOK11CeflHHH 11 nOfl11aM11H11, ,llOKTOpaHTa ce e KOHueHTpHpM BbPXY 11 aHM11311pM caMO
Te311 H3TOlfH11UH, KOHTO ,llOKa3BaT 3aIUO e Heo6xo,ll11MO ,lla ce pa3pa60TBaT HOB11 MeTO,ll11 3a
aHM113, KoeTO e 11 ueflTa Ha ,ll11CepTaUH5ITa.
B
lfaCTTa OTHaC5IIUa ce ,llO 113n0J13BaHHTe MaTepHaJIH H MeTO)1,H ca OrrHCaH11 TOlfHO 11
npeUH3HO Ha ,llOCTbneH e311K 113n0J13BaHHTe npOue,llYPH 11 MeTO,llHKH.
TIoBelfe OT ,llBe TpeT11
OT 06eMa Ha ,L(11cepTaU1151Ta ca OT,llefleHH 3a On11CaHHe
06Cb)K,llaHe Ha nOflYlfeH11Te pe3YJITaTH.
B
H
T0311 pa3,llefl Ha ,llHCepTaU1151Ta e Orr11CaHa CThrrKa
no CTbnKa 113BbpWeHaTa eKCnep11MeHTMHa pa60Ta ,llOBefla ,llO KpaHH1151 pe3YflTaT - Cb3,llaBaHe
Ha ,llBa HOB11, OpHr11HMHH aHMHT11lfH11 MeTO,ll11 3a e,llHOBpeMeHeH aHMH3 Ha aM11HOKHCeflHH11
H rrOfl11aM11H11. llBaTa MeTO,lla, KOHTO pelllaBaT e,ll11H 11 CbIUH npo6fleM aHM113
Ha
aM11HOK11CeflHH11
11
nOfl11aM11H11
B
6110flOrHlfH11
npo611,
11MaT
e,llHOBpeMeHeH
H5IK011
06IU11
rrpoue,llyp11 11 CThnK11, HO rrp11Te)J(aBaT CB051 HH,ll11B11,llYMHa OP11rHHMHOCT 11 YH11KMHOCT.
TIP11 OnHCaH11eTO Ha pa3pa60TBaHeTO Ha MeTO,ll11Te, ,llOKTOpaHTa e Cfle,llBM e,llHa 11 CbIUa
cxeMa Ha 113flQ)KeH11e -
3a,llaBaHe Ha 3a,llalf11Te 3a pewaBaHe, CTapTOBH YCflOB1151 Ha 6a3a
fl11TepaTypa, pa3pa60TBaHe Ha C06CTBeH11 YCflOB1151 3a aHM113, OnT11M11311paHe H BM11,ll11paHe
Ha KpaeH MeTO,ll 3a aHM113. OT,lleflH11Te eTan11 Ha pa3pa60TKaTa Cfle,llBaT e,llHa flOr11lfHa cxeMa
Ha 113flO)J(eH11e, K051TO n03BOfl5lBa 11 Ha CneU11M11CT11, K011TO ca BCTpaH11 OT 06flacrra, ,lla
nOflYlfaT 51CHa npe,llCTaBa 3a ,lleHCTB1151Ta Ha ,llOKTOpaHTa B rrpoueca Ha pa60Ta.
KmOlfOB
eTarr
OT
pa3pa60TKaTa
Ha
,llOKTOpaHTypaTa
e
11360pa
Ha
peareHT11
3a
,llep11BaT113aU1151 Ha aM11HOK11Cefl11H11 11 rrOflHaM11H11 C 9-cpflyopeH11flMeTOKC11Kap6oH11flHa rpyrra
(Fmoc, (cpMOK)). Fmoc rpynaTa e B OCHOBaTa Ha CbBpeMeHH1151 TBbp,llocpa3eH nerrT11,lleH
C11HTe3,
Kb,lleTO
aHM11T11lfHaTa
ce
113rr0J13Ba
rrpaKT11Ka
B
KaTO
BpeMeHHa
rrep110,lla
Ha
3aIU11THa
rpyna
pa3pa60TBaHe
Ha
3a
aM11HOrpyrr11.
,ll11CepTaU110HH1151
Ho
B
TPY,ll,
rrpaKT11lfeCK11 11Ma MHoro OrpaH11lfeHO rrp11flO)J(eH11e. Cfle,ll e,llHa uefleHaCOlfeHa CepH5I OT
eKCrrep11MeHT11 3a oueHKa Ha KalfeCTBaTa Ha pa3fl11lfH11 peareHT11.
B.
Jlo3aHoB npaB11 113BO,lla
qe
peareHT
Kap6oHl1nOKCl1)CYKlUIHl1MI1J],
e
3a
(F moc-Osu),
rrpeJ],11 TOBa HHKora He e mrrOJ13BaH 3a
aHarUITl1qHI1
'VI.-''-'''-'.''V
ca OrrTI1Ml13HpaHH H ycnOBH5ITa 3a
C TeCTBaHeTO Ha
Ha J],epliBaTH3aUHOHHaTa
Haql1H e
rro T0311
Ha
KaTO
HaMlipaHe
aueTOH
I1
Ha OrrTHMaflHO CbOTHOIlleHl1e Ha CMec OT
e
rrOCTl1rHaTa
OrrTl1MaflHa
CKOPOCT
MaKCIiMaflHO rrOJ],TI1CKaHe Ha
rrpOJ],bmKasaT l1
peaKUIUITa
B Trol1 rrOCOKa
propa6oTBaHe Ha BTOPH5I OnI-iCaH MeTOJ]"
KaTO B J],orrbnHeHHe ca
ce CTHra J],O
J],epl1Banl3aUI1OHHH5I
3a nbpBl1 rrbT Ha rrpoueJ],ypa Ha
rpyrra, KOHTO ce
rrpH
Ha
H3C,leJ],BaHII II e<j)eKTl1Te Ha rrOBI1lUeHaTa TeMrrepaTypa
B
Ha
"",,-,,,n.u.u
C Fmoc­
rrpl1 rrOBl1IlleHa TeMrrepaTypa.
'pe3YJITaTH H OOCbJJQlaHe" HaH-3HaQl1MO MHCTO e OTJ],eneHO Ha propa6oTBaHe
H
Ha xpOMaTorpa<j)CKHTe ycnoBHH Ha aHal1l13.
OT pa60TaTa e
e TaKa, 3alUOTO Trol1 qaCT
3a nOCTHraHe Ha rrOCTaBeHaTa uen.
B
Troll HaCOKa MoraT J],a 6bJ],aT OueH5IBaHll OT H5IKOnKO
TeXHOnOrIIQHll IJ~'L""''''''
rr031lUl11l
H360p Ha
rmUDC:Kll ycnOBl151 II BaflHJ],HpaHe Ha
B
MHoro CllCTeMaUI3llpaHO II rrOH5IKOra KOHCTaTHBHO orpOMeH
rro 06eM
caMO m60pa Ha rrOJ],XOJ],51lUa xpoMaTorpa<j)cKa
KonOHa, orrHcaH KaTO TeCTBaHe Ha KOnOHll a,6,B II T.H., BCblUHOCT peaflHO 03HaQaBa, 'Ie ca
peafl1l3HpaHl1 J],eceTKll
e
aHafl1l31l 3a J],bnbK
oT6enH3aHO,
qe
BCHKa
xpOMaTorpa<j)CKH ycnOBll51.
KonOHa
OT
e
e H
TeCTBaHa
C peafll131lpaHeTO Ha OrrllCaHH5I
MeTOJ], 3a aHafl1l3 rrpH H3rr0J13BaHe Ha
e
Ha
OT
0.1
0.5
KaKTO e
pa60Ta.
B
J],orrbnHeHlle,
B
pH.
CMeTKH TOBa
ca
nO-rOpHOTO
OT
CbC CTbrrKa Ha
OTJ],enHH
2.1
J],O
8.4
uu.l.n1lJU1
KOllTO
peaflII3HpaHH MHorOKpaTHO Ha pronHQHH KonOHH B xOJ],a Ha
e
1-10
Ha
KOHIleHTpaUH5ITa
Ha
MM H ca TeCTBaHH H5IKOJIKO KI1Cenl1HI1 KaTO MOJ],ynaTop Ha
caMO,
MOlKe J],a OCTaBll rpeIllHa
OCHOBHll51 pe3ynTaT,
B
3.8-4.5
pH eJ],HHllUll II BrrocneJ],CTBHe
e.llllHHua. no
B
Ha pH H
qe B xOJ],a Ha pa60Ta ca II3CJleJ],BaHH
CbC CTbIIKa OT
rro
3alUOTO
eJ],HO
Ha
3a 06eMa
cneJ], peafll131lpaHe Ha OrpOMHllH
HaCOQeHll KbM 1l360p H OIITHl\1H31lpaHe Ha xpOMaTorpa4>CKllTe
e cb3J],aBaHe na J],Ba
opHrHHaJJHH
XpOMaTOrpacpCKH
MeTO.lla 3a e.llHOBpeMeHeH
aHaJJH3
Ha aMHHOKHCenHHH
H
nOnHaMHHH B 6HOnOrW-IHH np06H. Te3H .llBa MeTO.lla ca Ha.lle){{.llHO BaJJH.llHpaHH BnOCne.llCTBHe
H ny6nHKYBaHH B peHOMHpaHH Me)l(.llYHapO.llHH CnHCaHH5I.
Pa36Hpa
ce,
pa3pa60TBaHeTO
Ha .llOpH
CbBbpmeHH
aHaJJHTW-IHH
npOue.llypH,
H5IMa
HHKaKbB CMHCbn, aKO Te He HaMep5IT npHnO){{eHHe B npaKTHKaTa. B .llHCepTaUH5ITa Ha B.
JIo3aHoB
ca
onHcaHH
caMO
H5IKOnKO
ceneKTHpaHH
npHno)KeHH5I
Ha
pa3pa60TeHHTe
aHaJJHTWIHH MeTO.llH , HO B KaLJeCTBOTO CH Ha HerOB HaYLJeH PbKOBO.llHTen Mora .lla BH YBep5I,
LJe Te3H MeTO.llH ca H3n0J13BaHH ycneulHo MHorOKpaTHO nOBeLJe. 3a TOBa CM5ITaM, LJe HaH­
CHnHO H HeocnopHMO .llOKa3aTenCTO 3a 3HaLJHMOCTTa H CTOHHOCTTa Ha .llHCepTaUHOHHH5I Tpy.ll,
e LJe pa3pa60TeHHTe aHaJJHTHLJHH MeTO.llH HMaT H me HMaT CBoeTO rrpaKTHLJeCKO npHno)KeHHe.
06eMa pa60Ta H3BbprneH B xO.lla Ha pa3pa60TBaHe Ha .llHCepTaUHOHHH5I rpY.ll e HaMepHn
11
B
7.419,
a
CBoeTO OTpa){{eHHe B .llBe HaYLJHH CTaTHH H e.llHH 0630p B KHHra Ha aHrnHHcKH e3HK.
TpHTe rry6nHKauHH BaJJeHTHH JI03aHoB e nbpBH aBTop. 0611UUIT HMnaKT (paKTOp e
HH.llHBH.llYaJJHH5I HMrraKT (paKTOp e
1.922.
UHTHpaHH5ITa Ha rry6nHKaUHHTe, cBbp3aHH C .llHCepTaUHOHHH5I TPY.ll, ca
UHTHpaHH5ITa ce OTHaC5IT Cal\lO 3a .llBeTe CTaTHH, KaTO rrbpBaTa e C
33,
97
Ha 6pOH.
a BTopaTa C
64
rr030BaBaHH5I B cnHCaHH5I H KHHrH Ha aHrnHHCKH e3HK.
ITpe.llCTaBeHH5IT OT B. JI03aHoB .llHCepTaUHoHeH TPY.ll BCblllHOCT e caMO e.llHa MaJJKa
LJaCT OT HerOBOTO .llOCeramHO HaYLJHO TBOpLJeCTBO, 3alllOTO TOH e cbaBTop B
rry6nHKaUHH C 06111 HMnaK cpaKTop
HMaT Ha.ll
340
50.8
(HH.llHBH.llYaJJHH5IT HMrraKT cpaKTop e
27
HaYLJHH
9.4),
KOHTO
n030BaBaHH5I B HaYLJHaTa mITepaTypa.
Y6e.lleHO
rrpe.llnaraM
Ha YBa){{aeMHTe
LJneHOBe
Ha
HaYLJHOTO
)I(YPH .lla rnaCYBaT
rrOnO){{HTenHa oueHKa Ha rrOCTHrHaTHTe pe3ynTaTH H rrpHHocH Ha .llHCepTaUHOHHH5I TPY.ll Ha
BaJJeHTHH
JIo3aHoB
.llHCepTaUHoHeH
aKa.lleMHLJHH5I
TPY.ll
CbCTas
H
H3pa35IBaM,
oTrOBap5I
B
Ha
Peny6nHKa
.llbn6oKOTo
BCHLJKH
CH
y6e){{.lleHHe,
H3HCKBaHH5I
.5bnrapH5I
H
Ha
Ha
3aKoHa
npaBHnHHKa
LJe
3a
3a
rrpe.llCTaBeHH5I
pa3BHTHe
Ha
pa3BHTHe
Ha
AKa.lleMHLJHH5I CbCTaB Ha MY- COCPH5I .
Bb3 OCHOBa Ha ropeH3nO)l(eHHTe .llOCTOHHcTBa Ha .llHCepTaUHOHHH5I TPY.ll rnaCYBaM
nOnO)l(HTenHO H npe.llnaraM Ha LJneHOBeTe Ha HaYLJHOTO )KYPH .lla npHCb.ll5IT Ha BaJJeHTHH
CToH1.IeB JI03aHoB 06pa30BaTenHaTa H HaYLJHa CTeneH ".llOKTOp".
COcpH5I , 07.02.2014 r
4n.KOp. npocp .ll-P BaHbo MHTeB .llM, .ll6H