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Zn Glu His His OH H H OH H O O N H C O N H OH

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OH
O
H
O
OH
OH
H2N
+
+
Arg145
H2N
+
His69
H
His196
H
OH N
2+
Zn
O
Glu72
C
H2N
His196
O
His69
H
O
+
H2N
NH2
N
H
N
Arg127
OH
2+
Glu270
O
Glu72
+
H2N
NH2
N
Arg127
H2N
O
H
Zn
O
Arg145
N
N
O
H N H
H
His69
O
H
N
2+
Zn
Ruptura Glu72
H
C O
His196
O
Glu270
N
H
H
O
H O
O
+
H2N
NH2
Glu270
N
Arg127
O
O
C 129
N
H
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CH CH CH CNH COOH H NH C NH NH CH CH CH CNH COOH H
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